Modelling decisions to undergo genetic testing for susceptibility to common health conditions: an ancillary study of the Multiplex Initiative.

Abstract:

:New genetic tests reveal risks for multiple conditions simultaneously, although little is understood about the psychological factors that affect testing uptake. We assessed a conceptual model called the multiplex genetic testing model (MGTM) using structural equation modelling. The MGTM delineates worry, perceived severity, perceived risk, response efficacy and attitudes towards testing as predictors of intentions and behaviour. Participants were 270 healthy insured adults aged 25-40 from the Multiplex Initiative conducted within a health care system in Detroit, MI, USA. Participants were offered a genetic test that assessed risk for eight common health conditions. Confirmatory factor analysis revealed that worry, perceived risk and severity clustered into two disease domains: cancer or metabolic conditions. Only perceived severity of metabolic conditions was correlated with general response efficacy (β = 0.13, p<0.05), which predicted general attitudes towards testing (β = 0.24, p<0.01). Consistent with our hypothesised model, attitudes towards testing were the strongest predictors of intentions to undergo testing (β = 0.49, p<0.01), which in turn predicted testing uptake (OR 17.7, β = 0.97, p<0.01). The MGTM explained a striking 48% of the variance in intentions and 94% of the variation in uptake. These findings support use of the MGTM to explain psychological predictors of testing for multiple health conditions.

journal_name

Psychol Health

journal_title

Psychology & health

authors

Wade CH,Shiloh S,Woolford SW,Roberts JS,Alford SH,Marteau TM,Biesecker BB

doi

10.1080/08870446.2011.586699

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

430-44

issue

4

eissn

0887-0446

issn

1476-8321

pii

938467198

journal_volume

27

pub_type

杂志文章
  • A longitudinal study of psychosocial distress in breast cancer: prevalence and risk factors.

    abstract::This longitudinal study was conducted among 102 women with non-metastasic breast cancer to identify the time evolution and prevalence of distress at specific times through diagnosis and treatment of disease: preliminary diagnosis, surgery, definitive diagnosis and chemotherapy. Additionally, the study aimed to examine...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2010.542814

    authors: Andreu Y,Galdón MJ,Durá E,Martínez P,Pérez S,Murgui S

    更新日期:2012-01-01 00:00:00

  • Associations between physical activity and core affects within and across days: a daily diary study.

    abstract:OBJECTIVE:The objective of the present study was to investigate (a) if daily physical activity at the within-person level is related to four different core affects the same evening, (b) if core affects in the evening predict physical activity the following day, and (c) if physical activity predicts core affects the fol...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2020.1745801

    authors: Ivarsson A,Stenling A,Weman Josefsson K,Höglind S,Lindwall M

    更新日期:2021-01-01 00:00:00

  • Effects of a brief multimodal online intervention on the intention to conduct sun protective behaviours through targeting illness representations about skin cancer: a randomized controlled trial.

    abstract::Objective: The incidence of skin cancer can be reduced by increasing sun protective behaviours. Based on the Common-Sense Model and the Intervention Mapping approach, a brief intervention targeting illness representations about skin cancer to increase the intention to conduct sun protective behaviours was developed an...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2020.1775831

    authors: Vollmann M,Engelhardt G,Salewski C

    更新日期:2020-06-11 00:00:00

  • Investigating lay beliefs regarding the effect of weight loss on health.

    abstract:OBJECTIVE:Individuals with obesity are often recommended weight loss for their health; however, the amount of weight loss that is recommended varies. Lay people's beliefs about weight loss could influence the types of behaviours they view as necessary for people with obesity. The present study explored lay beliefs rega...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2020.1792904

    authors: Black C,Vartanian LR,Faasse K

    更新日期:2020-07-28 00:00:00

  • A randomized controlled trial of expressive writing in breast cancer survivors with lymphedema.

    abstract:OBJECTIVE:Breast cancer survivors who develop lymphedema report poorer quality of life (QoL) than those without lymphedema. Expressive writing is a potential intervention to address QoL. DESIGN:Adult women (N = 107) with breast cancer and chronic Stage II lymphedema were randomised to writing about thoughts and feelin...

    journal_title:Psychology & health

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/08870446.2017.1307372

    authors: Sohl SJ,Dietrich MS,Wallston KA,Ridner SH

    更新日期:2017-07-01 00:00:00

  • Depression and marital status determine the 10-year (2004-2014) prognosis in patients with acute coronary syndrome: the GREECS study.

    abstract:BACKGROUND:The aim of the present work was to examine the association of depression and marital status, with the long-term prognosis of acute coronary syndrome (ACS), among a Greek sample of cardiac patients. METHODS:From October 2003 to September 2004, a sample of 2172 consecutive ACS patients from 6 hospitals was en...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2015.1034720

    authors: Notara V,Panagiotakos DB,Papataxiarchis E,Verdi M,Michalopoulou M,Tsompanaki E,Kogias Y,Stravopodis P,Papanagnou G,Zombolos S,Stergiouli I,Mantas Y,Pitsavos C

    更新日期:2015-01-01 00:00:00

  • 'It's like there are two people in my head': a phenomenological exploration of anorexia nervosa and its relationship to the self.

    abstract::This study explores the lived experience of anorexia nervosa from the perspective of those who use pro-recovery websites for eating disorders. Fourteen people participated in an online focus group or an e-interview. Data were analysed using interpretative phenomenological analysis. Participants described their disorde...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2011.595488

    authors: Williams S,Reid M

    更新日期:2012-01-01 00:00:00

  • Illness perception of migraineurs from the general population.

    abstract:OBJECTIVE:This study aims to describe the cognitive representations of migraine through the migraineurs' discourse. METHOD:A sample of subjects taken at random from a representative sample of the French general population is interviewed about their representations of migraine. A content analysis is performed using the...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2012.731059

    authors: Radat F,Koleck M,Foucaud J,Lantéri-Minet M,Lucas C,Massiou H,Nachit-Ouinekh F,El Hasnaoui A

    更新日期:2013-01-01 00:00:00

  • Smoking-specific communication and children's smoking onset: an extension of the theory of planned behaviour.

    abstract::The aim of this study was to test whether maternal smoking-specific communication and parental smoking related to smoking cognitions (i.e. attitude, self-efficacy and social norm) derived from the Theory of Planned Behaviour in association with smoking onset during preadolescence. A total of 1478 pairs of mothers and ...

    journal_title:Psychology & health

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1080/08870446.2012.677846

    authors: Hiemstra M,Otten R,van Schayck OC,Engels RC

    更新日期:2012-01-01 00:00:00

  • An observational study of social control, mood, and self-efficacy in couples during treatment for head and neck cancer.

    abstract:OBJECTIVE:Head and neck cancer (HNC) patients experience debilitating side effects, including abnormally reduced salivation and difficulty swallowing. Intensive self-care protocols are prescribed to control side effects and minimise discomfort, but non-adherence rates are high. Although spouses are in a prime position ...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2014.994633

    authors: Badr H,Yeung C,Lewis MA,Milbury K,Redd WH

    更新日期:2015-01-01 00:00:00

  • The impact of assuming the primary caregiver role following traumatic spinal cord injury: An interpretative phenomenological analysis of the spouse's experience.

    abstract::This study aimed to explore the lived experience of assuming the primary caregiver role in a group of spouses of individuals living with a traumatic spinal cord injury (SCI) (injuries ranged from paraplegia to quadriplegia). Individual in-depth interviews were conducted with 11 participants who were both the spouse an...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870440903038949

    authors: Dickson A,O'Brien G,Ward R,Allan D,O'Carroll R

    更新日期:2010-11-01 00:00:00

  • Predictors of posttraumatic stress symptoms and perceived health after an acute coronary syndrome: the role of experiential avoidance, anxiety sensitivity, and depressive symptoms.

    abstract::Objectives: The identification of psychological markers of the posttraumatic stress reaction after a cardiac event is relevant in the management of cardiovascular risk factors. The aim of the study to test the contribution of experiential avoidance, anxiety sensitivity, and depressive symptoms to acute coronary syndro...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2020.1761974

    authors: García-Encinas A,Ramírez-Maestre C,Esteve R,López-Martínez AE

    更新日期:2020-12-01 00:00:00

  • The relative role of nicotine dependence and smoking-related cognitions in adolescents' process of smoking cessation.

    abstract::The present study evaluates the role of distinct components of nicotine dependence (craving, withdrawal, behavioural dependence) in comparison to smoking-related cognitions (attitudes, perceived social approval, self-efficacy) in adolescent smoking cessation. In the process towards smoking cessation, we distinguish be...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2010.520715

    authors: Schuck K,Otten R,Engels RC,Kleinjan M

    更新日期:2011-10-01 00:00:00

  • 'So many women suffer in silence': a thematic analysis of women's written accounts of coping with endometriosis.

    abstract:OBJECTIVE:To understand women's experiences of coping with endometriosis, and impact on their lives. DESIGN:Women accessed an online questionnaire through a U.K.-based endometriosis charity website. METHODS:Thirty-four women, aged 22-56 years, with self-reported medically-diagnosed endometriosis, 30 of whom were Whit...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2018.1496252

    authors: Grogan S,Turley E,Cole J

    更新日期:2018-11-01 00:00:00

  • Understanding the prevalence and correlates of implicit theories of weight in the United States: Insights from a nationally representative sample.

    abstract:OBJECTIVES:The primary aim of this research is to understand how mindsets about weight controllability in the United States relate to population health. We examined the distribution of people's implicit theories of weight, from an incremental (controllable) to an entity (not controllable) mindset, in a nationally repre...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2017.1373112

    authors: Auster-Gussman LA,Rothman AJ

    更新日期:2018-04-01 00:00:00

  • Impact of alcohol on sexual decision making: Intentions to have unprotected sex.

    abstract::The impact of alcohol on intentions to have sex with a new partner and the antecedents of intentions were investigated in three studies (N = 139, 60, and 218, respectively). In all three studies, respondents were intoxicated or not intoxicated with alcohol and completed measures based on the Theory of Planned Behaviou...

    journal_title:Psychology & health

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/08870440701596551

    authors: Conner M,Sutherland E,Kennedy F,Grearly C,Berry C

    更新日期:2008-01-01 00:00:00

  • Affect and between-meal snacking in daily life: the moderating role of gender and age.

    abstract:OBJECTIVE:Affect-related energy intake from snacks remains relatively unexplored in daily life. This study examines the associations between momentary positive affect (PA) and momentary negative affect (NA) and subsequent energy intake from snacks. In addition, the moderating role of BMI, gender, age and level of educa...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2017.1380813

    authors: Wouters S,Jacobs N,Duif M,Lechner L,Thewissen V

    更新日期:2018-04-01 00:00:00

  • Amplified ambivalence: having a sibling with juvenile idiopathic arthritis.

    abstract::Despite increased awareness of family responses to chronic illness and disability, there is still a need to understand experiences of well siblings. We begin to address this issue by asking, 'What is it like to have a sibling with juvenile idiopathic arthritis?' (JIA). Eight families with an adolescent diagnosed with ...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/14768320701299906

    authors: Waite-Jones JM,Madill A

    更新日期:2008-01-01 00:00:00

  • Associations between risk perceptions and worry about common diseases: a between- and within-subjects examination.

    abstract::The relationships between worry and perceptions of likelihood and severity were evaluated across eight common diseases. Individual and disease variability in worry and perceptions were examined. 294 participants were recruited through the Multiplex Initiative, in which a genetic susceptibility test for eight common di...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2012.737464

    authors: Shiloh S,Wade CH,Roberts JS,Alford SH,Biesecker BB

    更新日期:2013-01-01 00:00:00

  • Psychometric evaluation of the Health-Risk Attitude Scale (HRAS-13): assessing the reliability, dimensionality and validity in the general population and a patient population.

    abstract:OBJECTIVES:The aim of this study was to assess the reliability, dimensionality and validity of the self-report questionnaire Health-Risk Attitude Scale (HRAS-13) in a sample of the general population and a patient population. METHODS:Sample 1 (n = 930) was recruited from the general population aged 18-65 years in the ...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2020.1851689

    authors: Huls SPI,van Osch SMC,Brouwer WBF,van Exel J,Stiggelbout AM

    更新日期:2020-12-01 00:00:00

  • Is dispositional optimism or dispositional pessimism predictive of ideal cardiovascular health? The Young Finns Study.

    abstract:OBJECTIVE:We examined the independent association between dispositional optimism compared to dispositional pessimism and ideal cardiovascular health (defined by the American Heart Association). DESIGN:A prospective design with a study sample of 1113 participants aged 24-39 years from the longitudinal Young Finns Study...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2015.1041394

    authors: Serlachius A,Pulkki-Råback L,Elovainio M,Hintsanen M,Mikkilä V,Laitinen TT,Jokela M,Rosenström T,Josefsson K,Juonala M,Lehtimäki T,Raitakari O,Keltikangas-Järvinen L

    更新日期:2015-01-01 00:00:00

  • Attacks on linking: stressors and identity challenges for mothers of daughters with long lasting anorexia nervosa.

    abstract::The purpose of the current study was to focus on the subjective experience of mothers of daughters with ongoing anorexia nervosa. Specifically, we explored the stressors faced by these mothers while coping with their daughters' illnesses; we also looked at how they experienced their maternal selves and roles, and thei...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2013.879135

    authors: Tuval-Mashiach R,Hasson-Ohayon I,Ilan A

    更新日期:2014-01-01 00:00:00

  • Motivational and behavioural consequences of self-affirmation interventions: a study of sunscreen use among women.

    abstract::The reported study compared the efficacy of three self-affirmation manipulations in reducing defensive processing and instigating behaviour change in response to personally relevant information about the health risks of sunbathing. White female sunbathers (N = 162) were recruited on a beach in the south of England. Pa...

    journal_title:Psychology & health

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/08870440801930320

    authors: Jessop DC,Simmonds LV,Sparks P

    更新日期:2009-06-01 00:00:00

  • The distressed (Type D) personality mediates the relationship between remembered parenting and psychological distress in cardiac patients.

    abstract:OBJECTIVE:Both the distressed (Type D) personality (i.e. the combination of negative affectivity and social inhibition traits) and dysfunctional parenting styles are associated with anxiety and depression. As parenting styles have been related to personality development, dysfunctional parenting styles may also be assoc...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2013.845889

    authors: Damen NL,Versteeg H,van Helmondt SJ,de Jaegere PP,van Geuns RJ,Meine MM,van Domburg RT,Pedersen SS

    更新日期:2014-01-01 00:00:00

  • Pride and physical activity: behavioural regulations as a motivational mechanism?

    abstract:OBJECTIVES:The purpose of this study was to examine the association between fitness-related pride and moderate-to-vigorous physical activity (MVPA). A secondary aim was to examine behavioural regulations consistent with organismic integration theory (OIT) as potential mechanisms of the pride-MVPA relationship. DESIGN:...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2015.1022547

    authors: Mack DE,Kouali D,Gilchrist JD,Sabiston CM

    更新日期:2015-01-01 00:00:00

  • Reducing behavioural risk factors for cancer: An affect regulation perspective.

    abstract::Nearly half of all cancer deaths are attributable to preventable causes, primarily unhealthy behaviours such as tobacco use, alcohol use and overeating. In this review, we argue that people engage in these behaviours, at least in part, as a means of regulating their affective states. To better understand why people en...

    journal_title:Psychology & health

    pub_type: 杂志文章,评审

    doi:10.1080/08870446.2017.1314480

    authors: O'Leary D,Suri G,Gross JJ

    更新日期:2018-01-01 00:00:00

  • You won't regret it (or love it) as much as you think: impact biases for everyday health behavior outcomes.

    abstract::When predicting the future, people tend to overestimate the intensity of their emotions, a phenomenon known as the impact bias. Design: In two studies, we examined the impact bias for health outcomes. In Study 1, participants were randomized to think about a negative health outcome in the future or one in the past. In...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2020.1795171

    authors: Dillard AJ,Dean KK,Gilbert H,Lipkus IM

    更新日期:2020-07-22 00:00:00

  • Emotional eating: eating when emotional or emotional about eating?

    abstract::This article examines the extent to which self-reported emotional eating is a predictor of unhealthy snack consumption or, alternatively, an expression of beliefs about the relation between emotions and eating derived from concerns about eating behaviour. Three studies were conducted. Study 1 (N = 151) and Study 2 (N ...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870440903207627

    authors: Adriaanse MA,de Ridder DT,Evers C

    更新日期:2011-01-01 00:00:00

  • A longitudinal study of patients' experiences of chronic low back pain using interpretative phenomenological analysis: changes and consistencies.

    abstract::This paper present data from the second and third rounds of a three-phase longitudinal research project exploring the 'lived experiences' of patients with chronic low-back pain (CLBP) in the United Kingdom. Qualitative, semi-structured interviews were conducted with eight participants 1 and 2 years after the first int...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870446.2011.630734

    authors: Snelgrove S,Edwards S,Liossi C

    更新日期:2013-01-01 00:00:00

  • Who cares, who bears, who benefits? Female spouses vicariously carry the burden after cancer diagnosis.

    abstract:BACKGROUND AND AIM:Among couples coping with cancer diagnosis, the effects of gender, role (patient vs. spouse) and patient relationship status (single vs. partnered) on quality of life (QoL) have been investigated with inconsistent results. The present study examined the impact of gender, role and relationship status ...

    journal_title:Psychology & health

    pub_type: 杂志文章

    doi:10.1080/08870440903418877

    authors: Kuenzler A,Hodgkinson K,Zindel A,Bargetzi M,Znoj HJ

    更新日期:2011-03-01 00:00:00