Abstract:
:Lichen planus (LP) is a chronic and remitting dermatosis that may be idiopathic or associated with underlying systemic diseases, such as hepatitis C virus. Although numerous cases of LP resolve spontaneously, many cases require systemic treatment. Several therapeutic advances have occurred in the last 10 years: acitretin (30 mg daily for 8 weeks) remains a first-line therapy (level B, controlled clinical trial >20 participants); systemic corticosteroids are second-line therapies (level C, clinical trial <20 participants, or larger trial without appropriate controls); and new data recommend against the use of tetracycline (level C). This article reviews the current status of systemic therapies for cutaneous LP.
journal_name
Cutisjournal_title
Cutisauthors
Asch S,Goldenberg Gsubject
Has Abstractpub_date
2011-03-01 00:00:00pages
129-34issue
3eissn
0011-4162issn
2326-6929journal_volume
87pub_type
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