Abstract：
:A small proportion of patients with alpha1-antitrypsin (alpha1AT) deficiency experience recurrent ulcerating panniculitis. Studies suggest that alpha1AT-deficiency panniculitis reflects an uncontrolled inflammatory process because of the serum's incapacity to neutralize proteolytic enzymes released by leukocytes in the skin. Dapsone is considered the treatment of choice for this entity, but it is limited by its side effects, especially hematologic ones. Tetracyclines have anticollagenase and anti-inflammatory activity and have been used successfully to treat this type of panniculitis. We report the case of a 42-year-old woman with recurrent alpha1AT-deficiency panniculitis who did not tolerate the side effects of dapsone or systemic corticosteroid. Minocycline treatment led to disappearance of lesions, and long-term administration prevented recurrences without evident negative side effects. We consider minocycline a safe treatment that allows control of alpha1AT-deficiency panniculitis.
journal_name
Cutisjournal_title
Cutisauthors
Ginarte M,Rosón E,Peteiro C,Toribio Jsubject
Has Abstractpub_date
2001-08-01 00:00:00pages
86-8issue
2eissn
0011-4162issn
2326-6929journal_volume
68pub_type
杂志文章相关文献
CUTIS文献大全abstract：:We report the case of a 6-week-old girl who presented with a pedunculated embryonal rhabdomyosarcoma arising in a giant congenital melanocytic nevus (GCMN) on her lower back. There was no associated leptomeningeal involvement. The patient underwent surgical resection of the rhabdomyosarcoma at age 2 months, with subse...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:A comparative split-face study of 20 participants with disseminated facial molluscum contagiosum (MC) and human immunodeficiency virus (HIV) infection was conducted to assess treatment with cryosurgery (left side of the face) versus trichloroacetic acid (TCA) 100% peels (right side of the face). A total of 2 treatment...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2009-06-01 00:00:00
abstract：:Total-body skin examination (TBSE) is the bedrock on which most general dermatologists' clinic days are built. Primarily performed for all-cause skin cancer detection and prevention, the clinical data gained and advice imparted during the patient visit disseminate safety guidelines and behavioral patterns that can sha...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2019-05-01 00:00:00
abstract：:A survey about sunbathing practices was performed on a summer holiday weekend at a Galveston beach. The likelihood of sunburn increased with increasing duration of sun exposure, with 100% of subjects experiencing sunburn after exposure > or = 4.5 hours. Men exhibited a significantly higher frequency of sunburn, employ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：:Pediatric psoriasis accounts for approximately one-third of all cases of psoriasis. Although pediatric psoriasis was always understood to be a chronic inflammatory dermatosis, recent data suggest that pediatric psoriasis, similar to its adult equivalent, is part of a generalized inflammatory diathesis associated with ...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：2015-03-01 00:00:00
abstract：:Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase are very common and effective treatments for hyperlipidemia. Epidermal cholesterol synthesis has been shown to be essential for maintaining the cutaneous barrier function. We present two patients who experienced cheilitis after beginning treatment...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:Unusual, discrete palmar and plantar symptoms observed in thirty of forty-seven children with dermatitis herpetiformis are described. The diagnosis was verified in every case by the demonstration of granular IgA deposits in the skin. Forty-five of the children showed villous atrophy in jejunal biopsy specimens. In fou...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:An example of intravascular papillary endothelial hyperplasia (Masson's pseudoangiosarcoma) of the skin of the forearm is presented. The clinical and pathologic features of the unusual lesion are described. Its benign, self-limited nature is emphasized, despite histopathologic features which may suggest the diagnosis ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Multiple systemic manifestations of renal cell carcinoma have been reported. The first case of a discoid lupus erythematosus-like syndrome and the third reported case of hypercalcemia associated with an elevated serum prostaglandin E2 level in a patient with renal cell carcinoma is presented herein. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1980-10-01 00:00:00
abstract：:Tinea nigra is a relatively uncommon dermatiaceous fungal infection, usually caused by Phaeoannellomyces werneckii, that may mimic a melanocytic lesion. We describe the value of epiluminescent dermoscopy of tinea nigra plantaris compared with other common diagnostic tools and procedures available (clinical appearance,...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:In the current scabies pandemic, classic scabies is seen less frequently and special forms are becoming more common. The diagnosis of scabies has become, therefore, a challenge for clinicians. The well-known scabietic burrow is seen only very rarely today and, therefore, pathognomonic as it is, the diagnosis of scabie...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:Molluscum contagiosum is an infection caused by a poxvirus that gives rise to small, benign, white, pink, or flesh-colored, umbilicated, raised papules or nodules located in the epidermal layer of the skin. The disease can be transmitted by direct bodily contact including sexual activity, fomites, or self-inoculation....
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：2004-03-01 00:00:00
abstract：:We describe a case in which a "punch biopsy" specimen of a conventional melanoma on the cheek of a 25-year-old man led to a problem in differentiating a desmoplastic malignant melanoma from cicatrix. The circumstances of this case raise the issue of whether desmoplastic melanoma can arise at the site of trauma within ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Six separate investigators following the methodology stipulated in a common protocol provided a data base of 124 patients with Rhus dermatitis, other contact dermatitis, or atopic dermatitis. In this double-blind study, one or two 1 ml (4.0 mg/ml) intramuscular injections of the new sodium phosphate ester of betametha...
journal_title：Cutis
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1976-01-01 00:00:00
abstract：:Cutaneous angiosarcoma is a rare aggressive malignancy of vascular origin that usually arises in the scalp or face of elderly men. We describe a case of primary cutaneous angiosarcoma with skin metastases and presumed metastases to the lung in a 58-year-old man who presented with persistent bloody pleural effusions, a...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:Pruritus can be due to a variety of factors and can often be difficult for a physician to manage. Often the etiology is psychosomatic, wherein a careful history is the key to proper diagnosis. Such a case is presented. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:Sulconazole nitrate 1.0 percent cream was compared to miconazole nitrate 2.0 percent cream in a double-blind, parallel study involving ninety-six patients with cutaneous dermatophytosis. Both agents were highly effective, with no statistically significant differences in the parameters studied. Among tinea pedis patien...
journal_title：Cutis
pub_type： 临床试验,杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：:Blue rubber bleb nevus syndrome is an uncommon hereditary systemic disorder characterized by localized vascular ectasia of the skin and gastrointestinal system. Review of patients reported to date with this disorder indicates that it has been described in only one black patient. We report a case of this syndrome in a ...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：1990-02-01 00:00:00
abstract：:Alopecia areata is a frequent and physiologically compelling form of hair loss. It is most common in children and young adults, but can affect people of any age. Although it is usually limited to patches on the scalp, it may involve the entire scalp and other hair-bearing regions of the body. It may be associated with...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
abstract：:Extramammary Paget disease (EMPD) is a malignant tumor typically found in apocrine-rich areas of the skin, particularly in the anogenital region. Some germinative apocrine-differentiating cells might exist on the trunk, preferentially in Asian individuals. Ectopic EMPD arises in nonapocrine-bearing areas, specifically...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2018-06-01 00:00:00
abstract：:Onchocerciasis, or river blindness, is a parasitic infection caused by the filarial nematode, Onchocerca volvulus. It infects 18 million people worldwide, but is rarely seen in the United States. It is one of the leading causes of blindness in the developing world. Although onchocerciasis is also known as river blindn...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:We report two patients with ecchymotic patches that did not suggest the diagnosis of Kaposi's sarcoma. The principal complaint of one patient was facial and periorbital edema with bilateral periorbital ecchymosis. On his trunk were patches resembling pityriasis rosea-like Kaposi's sarcoma. Both types of lesions proved...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：:A 63-year-old woman presented with a single plaque on her left earlobe that was shown to be a B-cell lymphoma on histopathologic examination. Immunohistochemical studies on the paraffin-embedded tissue and flow cytometry of fresh tissue helped characterize the neoplasm. She had no other systemic involvement and a diag...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:Uncomplicated skin and skin structure infections commonly are caused by Staphylococcus aureus and Streptococcus pyogenes. Cefdinir, an extended spectrum, third-generation cephalosporin is a safe and effective means of treating skin infections caused by these organisms, as well as many gram-negative pathogens. This art...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：2004-05-01 00:00:00
abstract：:Fat embolism syndrome is a life-threatening disease with cutaneous manifestations that occur most commonly after fractures of a long bone. The syndrome consists of a triad of dermatologic, pulmonic, and neurologic involvement. Because no major dermatologic journal has reviewed this syndrome in more than five years, we...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1986-07-01 00:00:00
abstract：:The effectiveness of sulfur 2 percent and salicylic acid 2 percent either alone or in combination in a shampoo base was determined in a double-blind controlled study using two methods of evaluation: clinical assessment of scaling and corneocyte counts (the number of desquamating cells/cm2). Forty-eight subjects (twent...
journal_title：Cutis
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1987-06-01 00:00:00
abstract：:Atopic dermatitis and Ritter's disease in infants and children frequently present diagnostic as well as therapeutic problems. Both conditions are characterized by generalized exfoliative dermatitis, and are prone to recurrent infections with Staphylococcus. However, in Ritter's disease, it has been shown that these ar...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:Topical therapy for rosacea aims to reduce inflammatory lesions and decrease erythema but can carry side effects such as stinging, pruritus, and burning. Metronidazole and azelaic acid gel 15% are U.S. Food and Drug Administration-approved for the treatment of rosacea. The current study was conducted to assess the cum...
journal_title：Cutis
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-04-01 00:00:00
abstract：:When the tongue comes in contact with frozen metal or nonmoist ice cubes, it becomes adherent. The author illustrates such an example experienced by his son. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:Toxic epidermal necrolysis (TEN) is a rare but life-threatening disorder of children and adults in which the skin peels off in sheets and mucosal surfaces slough. It is best viewed as a severe from of erythema multiforme, with even more extreme involvement than one sees with the Stevens-Johnson syndrome (SJS). However...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
