Abstract:
:Improvement in vehicle design may improve the delivery of drugs to the target site. A clinical trial was performed to evaluate an improved vehicle for topical benzoyl peroxide. Thirty-nine subjects participated in a split-face, double-blind trial of topical benzoyl peroxide 5 percent versus benzoyl peroxide 5 percent in 8 percent urea. All subjects had grade II or III acne as described by Pillsbury. Study solutions were randomly assigned to a selected side of the subject's face and applied twice a day to the appropriate side of the face for eight weeks. Total and inflammatory lesion counts were performed by the same investigator during the eight weeks of study at biweekly intervals. No overall differences in the response to the study preparations were observed when assessed objectively and subjectively.
journal_name
Cutisjournal_title
Cutisauthors
Prince RA,Harris JM,Maroc JAsubject
Has Abstractpub_date
1982-06-01 00:00:00pages
638-40, 644-5issue
6eissn
0011-4162issn
2326-6929journal_volume
29pub_type
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