Comparative trial of benzoyl peroxide versus benzoyl peroxide with urea in inflammatory acne.

Abstract:

:Improvement in vehicle design may improve the delivery of drugs to the target site. A clinical trial was performed to evaluate an improved vehicle for topical benzoyl peroxide. Thirty-nine subjects participated in a split-face, double-blind trial of topical benzoyl peroxide 5 percent versus benzoyl peroxide 5 percent in 8 percent urea. All subjects had grade II or III acne as described by Pillsbury. Study solutions were randomly assigned to a selected side of the subject's face and applied twice a day to the appropriate side of the face for eight weeks. Total and inflammatory lesion counts were performed by the same investigator during the eight weeks of study at biweekly intervals. No overall differences in the response to the study preparations were observed when assessed objectively and subjectively.

journal_name

Cutis

journal_title

Cutis

authors

Prince RA,Harris JM,Maroc JA

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

638-40, 644-5

issue

6

eissn

0011-4162

issn

2326-6929

journal_volume

29

pub_type

临床试验,杂志文章,随机对照试验

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