Abstract：
:The observation that endocardial fibroelastosis (EFE) can result from an immune response to maternal autoantibody deposition in the fetal myocardium raises the possibility that the fetal immune system may contribute to the pathogenesis of idiopathic EFE and dilated cardiomyopathy (DCM). This study sought to characterize myocardial immune cell presence in fetuses and neonates with idiopathic EFE + DCM, in those with EFE + structural heart disease, and in normal control subjects. Paraffin tissue sections from fetuses identified from the pathology database were stained for B cell, T cell, macrophage, and general hematopoietic cell surface markers. Of the 14 fetuses included in the study, 5 had EFE + DCM, 4 had EFE + structural heart disease, and 5 were normal control fetuses. The EFE + DCM group had fewer B cells than the control group (0.15 vs. 0.44 cells/mm(2); p = 0.005). The EFE + heart disease group had both fewer B cells (0.18 vs. 0.44 cells/mm(2); p = 0.08) and T cells (0.29 vs. 0.80 cells/mm(2); p = 0.04) than the control group. The CD4/CD8 ratio was similar in the EFE + DCM and EFE + heart disease groups (1.0 vs. 0.9; p = 0.17) but higher in the EFE + DCM group than in the control group (0.9 vs. 0.3; p = 0.03). The myocardium of fetuses with EFE contains fewer B and T lymphocytes than normal control fetuses.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Fernandes NM,Taylor GP,Manlhiot C,McCrindle BW,Ho M,Miner SE,Atkinson A,Jaeggi ET,Nield LEdoi
10.1007/s00246-011-9980-1subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1088-95issue
8eissn
0172-0643issn
1432-1971journal_volume
32pub_type
杂志文章abstract：:This retrospective study aimed to determine the superior vena cava (SVC) and left innominate vein (INV) normative cross-sectional area in children noninvasively using age as a predictor and also to compare the correlation of the area measured with the diameter on multidetector computed tomography (MDCT). Analysis of t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0893-7
更新日期：2014-08-01 00:00:00
abstract：:With the advent of cardiac magnetic resonance imaging and high-resolution echocardiography, cardiac catheterization is unnecessary in clinical protocols in the "routine" single ventricle patient. Catheterization adds little to clinical care in these cases, and there are significant risks and costs associated with it. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-004-0960-6
更新日期：2005-03-01 00:00:00
abstract：:The purpose of the study was to evaluate school-age developmental and educational outcomes for children with and without a cardiac procedure in the first year of life to improve understanding of longer-term neurodevelopmental outcomes in children who have had a cardiac procedure for congenital heart disease, the most ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2029-y
更新日期：2019-03-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-012-0466-6
更新日期：2013-02-01 00:00:00
abstract：:This report aims to summarize and evaluate the efficacy and experience of reintervention for children with postoperative pulmonary venous restenosis. Clinical data from 61 patients with postoperative pulmonary venous restenosis who underwent reintervention at Shanghai Children's Medical Center (SCMC) from September 20...
journal_title：Pediatric cardiology
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doi：10.1007/s00246-019-02098-z
更新日期：2019-06-01 00:00:00
abstract：:Rhabdomyoma is the most common primary cardiac tumor in infants and children and is often associated with tuberous sclerosis. Surgical resection may be indicated and, if so, is usually curative. We describe a rhabdomyoma in an infant who presented with severe myocardial ischemia necessitating orthotopic heart transpla...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794197
更新日期：1995-07-01 00:00:00
abstract：:Little has been published about specific problems that may occur during long-distance transports of newborn cardiac patients. During a 4-year period after centralization of pediatric heart surgery in Sweden, 286 transports were prospectively investigated. A majority (77.3%) of the transports were carried out by nonspe...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010254
更新日期：2001-09-01 00:00:00
abstract：:This case discusses a Shone's variant with small left ventricle and mitral valve, bicuspid aortic valve, coarctation of the aorta, an unusual arrangement of atrial appendages, and partially anomalous pulmonary venous drainage due to a deviated atrial septum. The left atrial appendage could be directly entered from the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-1364-6
更新日期：2006-09-01 00:00:00
abstract：:Our objective was to evaluate and highlight the significance of epigastric tenderness in children and adolescents with chest pain. In a 26-months period, patients who were referred for pediatri cardiology evaluation at Shiraz University of Medical Sciences with chief complaint of chest pain were studied. Patients with...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2003-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02422-y
更新日期：2020-12-01 00:00:00
abstract：:The patient safety movement and human factors studies are becoming an increasingly important part of everyday clinical practice. Pediatric cardiac surgery is a high-risk field that is very much dependent on safe practices and continuous research into improvement of outcomes. This article reviews the main research fram...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-006-1448-3
更新日期：2007-03-01 00:00:00
abstract：:Changes in ventricular geometry are often seen in patients with right ventricular hypertension secondary to pulmonary hypertension (PH). Progressive systolic bowing of the inter-ventricular septum occurs with increasing right ventricular pressure (RVp) and can be quantified with the left ventricular end-systolic eccen...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1317-z
更新日期：2016-03-01 00:00:00
abstract：:This study aimed to determine the dimensions of the thoracic aorta and the predictors of aortic dimensions in girls and young women with Turner syndrome (TS). A cross-sectional study was performed at a secondary care center. The study compared 41 TS patients with 50 healthy age-matched control subjects. The mean age o...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9626-8
更新日期：2010-05-01 00:00:00
abstract：:The objective of this study was to compare histopathological changes in hypoplastic left heart syndrome right ventricles (RV) of patients undergoing Sano and modified Blalock-Taussig (MBT) shunt and correlate them with echocardiographic findings. Myocardial tissue samples were obtained from hearts with Sano or MBT shu...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0462-x
更新日期：2013-02-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-9915-x
更新日期：2011-06-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0925-3
更新日期：2014-10-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9016-z
更新日期：2008-01-01 00:00:00
abstract：:In chronic aortic insufficiency (AI), left-ventricular (LV) dysfunction must be detected early to allow timely surgery. Strain and strain rate have been used for this purpose in adults, but the value of this method in pediatric AI has not been established. Forty patients with moderate to severe AI were included in thi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0646-z
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:This study aimed to measure and compare right ventricular (RV) function in normal infants and those with pulmonary hypertension (PHT) using the myocardial performance index (RVMPI) and to investigate the relationship between RV function and pulmonary artery pressure. METHODS:A case-control study measured RV...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9285-1
更新日期：2009-02-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1871-2
更新日期：2018-08-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0714-4
更新日期：2013-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-1274-z
更新日期：2006-05-01 00:00:00
abstract：:The Norwood procedure with a modified Blalock-Taussig shunt (MBTS) is the first of the three-stage surgical palliation for infants with hypoplastic left heart syndrome. We report a patient with schistocytic hemolytic anemia that developed following a right MBTS with a Gore-Tex graft. Hemolysis associated with a MBTS h...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-1410-4
更新日期：2007-05-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1994-5
更新日期：2019-02-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0563-6
更新日期：2013-04-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796330
更新日期：1994-05-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0449-7
更新日期：2013-02-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794187
更新日期：1995-07-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9381-2
更新日期：2009-05-01 00:00:00
abstract：:We report a 4-month-old infant with torsade de pointes secondary to procainamide treatment. The infant presented with atrial flutter and converted to normal sinus rhythm with intravenous procainamide. Oral procainamide therapy was initiated as the infusion was tapered, and the patient subsequently developed incessant ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796823
更新日期：1995-03-01 00:00:00
