Abstract：
:Changes in ventricular geometry are often seen in patients with right ventricular hypertension secondary to pulmonary hypertension (PH). Progressive systolic bowing of the inter-ventricular septum occurs with increasing right ventricular pressure (RVp) and can be quantified with the left ventricular end-systolic eccentricity index (LVEI). Only limited data exist in children to evaluate the relationship between the LVEI and invasive RVp. We sought to assess the correlation between the LVEI and an invasively measured peak systolic RVp to aortic pressure (pAo) ratio. Medical records of patients undergoing echocardiography within 30 days of right and left heart catheterization for evaluation of PH between February 2009 and March 2014 were retrospectively reviewed. Forty-six studies in 29 subjects (median age 3.8 years, 46 % female), with a median time from echocardiogram to catheterization of -1.0 days, were included for analysis. The mean LVEI was 1.6 ± 0.5, and mean RVp/pAo ratio was 0.68 ± 0.26. There was a significant positive correlation (r = 0.76, p < 0.001) between LVEI and RVp/pAo ratio. ROC analysis demonstrated an area under the curve = 0.91 for prediction of RVp/pAo >0.50 by the LVEI. An LVEI >1.48 had a sensitivity of 76 % and specificity of 100 % in predicting RVp/pAo >0.50, while an LVEI >1.24 had a sensitivity of 88 % and specificity of 83 %. Echocardiographically derived LVEI is strongly correlated with invasively determined RVp/pAo ratio. In combination with other noninvasive measures of RVp, LVEI may help minimize the need for invasive patient evaluation.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Averin K,Michelfelder E,Sticka J,Cash M,Hirsch Rdoi
10.1007/s00246-015-1317-zsubject
Has Abstractpub_date
2016-03-01 00:00:00pages
575-81issue
3eissn
0172-0643issn
1432-1971pii
10.1007/s00246-015-1317-zjournal_volume
37pub_type
杂志文章abstract：:Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a heritable cardiomyopathy characterized by fibro-fatty replacement of right ventricular myocardium. Diagnostic criteria, established in 1994 and modified in 2010, are based on predominately adult manifestations of ARVC/D. The goal of this paper is ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1327-x
更新日期：2016-04-01 00:00:00
abstract：:Congenital heart defects (CHDs) are the leading cause of death in infants under 1 year of age. Aberrations in the expression and function of cardiac transcription factors (TFs) are a major contributor to CHDs. Despite the numerous studies undertaken to functionally characterize these TFs, their exact role in different...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02099-y
更新日期：2019-06-01 00:00:00
abstract：:The treatment of recurrent supraventricular tachycardia in a 3-week-old infant is described. Multiple doses of adenosine were used successfully to convert the dysrhythmia, without adverse effects or apparent tachyphylaxis. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900222
更新日期：1997-11-01 00:00:00
abstract：:We describe two cases of left-side pulmonary vein obstruction observed after the arterial switch operation (Jatene) for D-transposition of the great arteries. This appears to be related to left-sided pulmonary vein obstruction occurring coincidently with D-transposition of the great arteries, rather than a consequence...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900180
更新日期：1997-07-01 00:00:00
abstract：:M-mode and 2-dimensional (2D) echocardiographic imaging are routinely used to quantify left-ventricular (LV) size and function in pediatric patients with dilated cardiomyopathy (DCM). The reproducibility of and correlation between these techniques are unknown. This analysis sought to compare interreader, intrareader, ...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s00246-013-0835-9
更新日期：2014-04-01 00:00:00
abstract：:We report a case of a 12-year-old boy with severe congenital aortic stenosis in whom magnetic resonance imaging (MRI) with delayed contrast enhancement demonstrated extensive subendocardial hyperenhancement within the left ventricle. The hyperenhancement was confirmed to be subendocardial infarct and fibrosis by histo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-5891-3
更新日期：2006-05-01 00:00:00
abstract：:Systemic candidiasis developed in a seven-week-old premature baby after 6 weeks treatment with antibiotics for suspected septicemia. At that time the echocardiogram showed a dense layer of echoes posteriorly to the anterior tricuspid leaflet during atrial systole. The diagnosis of Candida endocarditis with vegetations...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02281007
更新日期：1983-01-01 00:00:00
abstract：:The transplanted heart experiences numerous hemodynamic changes during and after cardiac transplantation. This study sought to evaluate the left ventricular myocardial mechanics in the pediatric heart transplant population using Velocity Vector Imaging (VVI). This study retrospectively evaluated 28 heart transplant re...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0205-z
更新日期：2012-06-01 00:00:00
abstract：:A 6-year-old girl was found to have a combination of accessory mitral valve tissue and subaortic membrane. The association caused left ventricular outflow tract obstruction leading to severe left ventricular dysfunction. Surgical relief of the obstruction resulted in immediate improvement of ventricular function. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-5023-7
更新日期：2002-01-01 00:00:00
abstract：:Our purpose was to evaluate the impact of suspicion or confirmation of heart disease on the physical and psychosocial health of children. We utilized the Child Health Questionnaire (CHQ PF-50). Children ages 5 to 18 years attending a general cardiology clinic were eligible. Those with primary noncardiac diagnoses unre...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0348-z
更新日期：2004-01-01 00:00:00
abstract：:We report a unique case of tricuspid and pulmonary atresia with idiopathic progressive ductus arteriosus restriction in utero. Diligent predelivery planning and a controlled delivery environment led to a favorable outcome. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0391-8
更新日期：2013-08-01 00:00:00
abstract：:Calculating pulmonary vascular resistance is important in many fields of medicine. Although the influence of hematocrit on calculated resistance has been known for many years, it is rare to find the appropriate corrections in published articles. This review discusses the relationship between viscosity and resistance a...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-011-9954-3
更新日期：2011-06-01 00:00:00
abstract：:At the University of California Davis Medical Center, a screening fetal ultrasound examination (level I or II) incorporates a comprehensive segmental evaluation of the fetal heart. This study evaluated the reliability of the fetal ultrasound exam in the detection of abnormal heart anatomy. Our retrospective study revi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-0073-4
更新日期：2002-11-01 00:00:00
abstract：:This study aimed to assess the impact of integrating a simulation-based education module into an extracorporeal membrane oxygenation (ECMO) curriculum on novice learners and to test the duration of time that skills obtained during this training exercise were retained. The authors hypothesized that multidisciplinary, s...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0490-6
更新日期：2013-03-01 00:00:00
abstract：:Left ventricular hypertrophy is an adaptive mechanism in children undergoing chronic dialysis to improve contractility at rest. The aim of this study was to determine the left ventricular performance and contractility reserve by "dobutamine stress echocardiography" in children undergoing chronic dialysis. Thirty-five ...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00246-010-9721-x
更新日期：2010-10-01 00:00:00
abstract：:A 2-year-old girl with cor triatriatum with unroofed coronary sinus and persistent left superior vena cava underwent preoperative radiofrequency catheter ablation for atrial tachycardia attack that developed after admission to our hospital. The procedure was not successful. Cryoablation was successfully performed duri...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-002-0376-0
更新日期：2003-09-01 00:00:00
abstract：:Restrictive cardiomyopathy (RCM) is characterized by irreversible diastolic dysfunction with preserved systolic function. The aim of this study was to investigate the presence of impaired ventricular contractility even in the presence of normal ejection fraction (EF) in children with RCM. Longitudinal Doppler tissue v...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-9948-1
更新日期：2011-06-01 00:00:00
abstract：:Sudden death accounts for up to 43% of all deaths in patients with familial dysautonomia (FD). The classic features of FD, namely, autonomic dysfunction, high blood pressure, and blood pressure labiality, are all risk factors for cardiac remodeling and hypertrophy. Myocardial remodeling and hypertrophy are independent...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9497-z
更新日期：2009-11-01 00:00:00
abstract：:Contrary to acquired arteriovenous fistulas, the congenital malformations are very rare. Here we report a case of congenital arteriovenous fistula forming a communication between the right subclavian artery to subclavian vein. To our knowledge, there is no similar case in which an infant has been successfully operated...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010056
更新日期：2000-05-01 00:00:00
abstract：:We report hemodynamic findings in two patients with pulmonary atresia and intact ventricular septum (PAIVS) after "one-and-a-half ventricle repair" and placement of a bidirectional Glenn shunt using four-dimensional (4D) flow magnetic resonance imaging. Quantification of flow and analysis of flow patterns revealed the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0288-6
更新日期：2013-02-01 00:00:00
abstract：:Operative survival after the Norwood procedure has significantly improved during the past 10 years. However, there remains attrition among Norwood survivors before reaching planned second-stage palliation. The purpose of this study was to evaluate potential risk factors for interstage mortality among Norwood survivors...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0776-4
更新日期：2005-07-01 00:00:00
abstract：:Natriuretic peptides (NP) are released from the heart in response to pressure and volume overload. The biologic properties of NPs include counterregulation of the rennin-angiotensin-aldosterone pathway and a decrease in sympathetic tone resulting in diuresis, natriuresis, and vasodilation. Natriuretic peptides help to...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-010-9758-x
更新日期：2010-11-01 00:00:00
abstract：:Using the Doppler technique, this study compared the prenatal and postnatal flow patterns of an infant with cerebral arteriovenous (AV) malformation. Fetal right ventricular end-diastolic dimension was 1.7 cm with right ventricular ejection equaling 66% of the combined cardiac output. Diastolic flow was reversed in th...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00801914
更新日期：1995-05-01 00:00:00
abstract：:Magnetocardiographic mapping was performed on a 2-year-old boy who suffered from the Wolff-Parkinson-White syndrome in association with a complex congenital heart defect. The pre-excitation site was determined noninvasively from the measured cardiac magnetic fields. The location was in the same anatomic region as foun...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02310333
更新日期：1995-01-01 00:00:00
abstract：:Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone res...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900292
更新日期：1998-05-01 00:00:00
abstract：:The Norwood procedure with a modified Blalock-Taussig shunt (MBTS) is the first of the three-stage surgical palliation for infants with hypoplastic left heart syndrome. We report a patient with schistocytic hemolytic anemia that developed following a right MBTS with a Gore-Tex graft. Hemolysis associated with a MBTS h...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-1410-4
更新日期：2007-05-01 00:00:00
abstract：:Congenital heart disease (CHD) is the most common congenital anomaly, affecting 1 % of live births. The field of pediatric cardiology has witnessed major advances over the past 25 years triggered by research initiatives focusing on CHD. However, large disparities exist in research capabilities between Arab developing ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-012-0466-6
更新日期：2013-02-01 00:00:00
abstract：:The etiology and pathogenesis of Kawasaki disease (KD) is largely unknown. Certain demographic factors and laboratory findings are predictive of the development of coronary artery (CA) aneurysms. The objectives of this study were to determine the epidemiology of KD patients in an urban hospital and determine risk fact...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-0916-5
更新日期：2005-11-01 00:00:00
abstract：:Studies of larger patient groups for systematic assessment of the anatomical accuracy of magnetic resonance imaging (MRI) for partial anomalous pulmonary venous drainage (PAPVD) have been performed so far only in adults. This study was undertaken to evaluate whether MRI can precisely depict pulmonary venous anatomy in...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9367-0
更新日期：2009-05-01 00:00:00
abstract：:A case of aneurysmal enlargement of the right atrium was found accidentally during a routine examination. The patient was asymptomatic and free of palpitations or proven rhythm disturbances. The results of echocardiography, magnetic resonance imaging, and cardiac catheterization excluded cardiac malformation, which co...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900341
更新日期：1998-09-01 00:00:00
