Abstract:
:Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone resulted in the normalization of echocardiographic findings. Based on these observations, a randomized, multicenter treatment study of chronic myocarditis in children (TCMC) has been initiated.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Schmaltz AA,Demel KP,Kallenberg R,Neudorf U,Kandolf R,Klingel K,Bültmann Bdoi
10.1007/s002469900292subject
Has Abstractpub_date
1998-05-01 00:00:00pages
235-9issue
3eissn
0172-0643issn
1432-1971journal_volume
19pub_type
杂志文章abstract::B-type natriuretic peptide (BNP) reflects volume overload on left ventricle and pulmonary hypertension (PH) in patients with ventricular septal defect (VSD). Pulmonary vascular resistance (PVR) has been reported to correlate positively with BNP in VSD patients with various degrees of PH. We aimed to investigate the re...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-007-9037-7
更新日期:2008-01-01 00:00:00
abstract::We describe the first report of an infant who was born with hypoplastic left heart syndrome and significant pulmonary stenosis. He was successfully palliated with multiple cardiac catheterization interventions while waiting for cardiac transplantation. This unusual constellation of heart defects is an entity that is r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-004-0856-5
更新日期:2005-09-01 00:00:00
abstract::Non-invasive evaluation of right ventricular (RV) systolic function in neonates with pulmonary hypertension (PH) with traditional metrics including RV fractional area change (FAC) and tricuspid annular systolic plane excursion (TAPSE) has improved outcomes. Apical three-chamber (3C) RV-FAC, a novel tripartite assessme...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02376-1
更新日期:2020-08-01 00:00:00
abstract::Transcatheter closure of atrial septal defects (ASDs) has become a routine procedure in many countries of the world. It spares many patients cardiac surgery and has proven efficacy in long-term studies. Device improvements have resulted in a continuous reduction of complications and of residual shunt frequency. ASD cl...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-1011-7
更新日期:2005-05-01 00:00:00
abstract::This report describes a case involving the rare combination of persistent truncus arteriosus type A2, double aortic arch, and mitral stenosis. At the age of 26 days, the patient underwent division of the right-sided aortic arch with tracheal compression and bilateral pulmonary banding. Fontan completion was successful...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0572-5
更新日期:2013-01-01 00:00:00
abstract::Midodrine hydrochloride is a potent peripherally-acting alpha1 agonist that is well absorbed and rapidly metabolized to its active metabolite. It has been used for the treatment of refractory syncope but has the important side effect of supine hypertension. A 10-year-old boy with severe symptomatic orthostatic hypoten...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-006-0169-y
更新日期:2007-07-01 00:00:00
abstract::A 6-year-old girl with evidence of a parahisian accessory pathway on a baseline electrocardiogram underwent successful catheter ablation using magnetic navigation. Magnetic remote controlled ablation eliminated the parahisian pathway with the first radiofrequency application. A second anterolaterally located concealed...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0540-0
更新日期:2013-03-01 00:00:00
abstract::This review outlines the morphologic and pathogenetic characteristics of congenital polyvalvular disease. Two cases are used for exemplification. The macroscopic and histologic features of the valves as well as associated cardiac lesions and clinical syndromes are described, followed by a discussion of morphogenesis o...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s002460010169
更新日期:2001-03-01 00:00:00
abstract::During the development of so-called aneurysmal transformation of perimembranous ventricular septal defects (pmVSD), tricuspid valve (TV) morphology and function may be altered resulting in left ventricular (LV) to right atrial (RA) shunting. The feasibility and outcome of interventional closure of these pmVSD has not ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1170-0
更新日期:2015-10-01 00:00:00
abstract::Isolation of the left innominate artery arising from the ductus arteriosus is a rare clinical entity with only nine cases being reported in the literature [5, 7, 8]. We describe a case consisting of tetralogy of Fallot, right aortic arch, and isolation of the left innominate artery arising from a left-sided ductus art...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010154
更新日期:2001-01-01 00:00:00
abstract::Previous studies have evaluated left ventricular dimensions in children using two-dimensional echocardiography, but there is little information on gender differences and on the longitudinal development of the dimensions of the left ventricle. Our objective was to assess, by two-dimensional echocardiography, the normal...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02505207
更新日期:1996-05-01 00:00:00
abstract::Conotruncal cardiac defects are partially prevented by maternal folic acid supplementation. However, the biochemical mechanism is unknown. Maternal autoantibodies to folate receptors, previously associated with increased risk for neural tube defects, also may account for this effect. This study aimed to examine the ti...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0485-3
更新日期:2013-03-01 00:00:00
abstract::A 2-year-old girl with cor triatriatum with unroofed coronary sinus and persistent left superior vena cava underwent preoperative radiofrequency catheter ablation for atrial tachycardia attack that developed after admission to our hospital. The procedure was not successful. Cryoablation was successfully performed duri...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-002-0376-0
更新日期:2003-09-01 00:00:00
abstract::Crossed pulmonary arteries (CPAs) are a rare abnormality in which the ostium of the left pulmonary artery originates superior to the right pulmonary artery and to its right. Recognition of this rare pathology is important because it generally is accompanied by other congenital heart defects, extracardiac anomalies, an...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0714-4
更新日期:2013-01-01 00:00:00
abstract::Congenital diverticulum of the ventricle is a rare disease, but most cases of congenital left ventricular diverticula are asymptomatic. We present a child with congenital left ventricular diverticulum whose routine electrocardiographic examination showed T-wave inversion in inferior and V4 to V6 leads. He was successf...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9719-4
更新日期:2010-08-01 00:00:00
abstract::This study is presented to identify and characterize the spectrum of the cardiovascular anomalies in children presenting with Williams-Beuren syndrome and cardiovascular anomalies at The Hospital for Sick Children, Toronto from 1966 to 1988. Forty-nine children were diagnosed and followed. The female to male ratio was...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02310569
更新日期:1991-10-01 00:00:00
abstract::Right ventricular (RV) remodeling in hypoplastic left heart syndrome (HLHS) begins prenatally and continues through staged palliations. However, it is unclear if the most marked observed remodeling post-Norwood is secondary to cardiopulmonary bypass (CPB) exposure or if it is an adaptation intrinsic to the systemic RV...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02482-0
更新日期:2020-10-10 00:00:00
abstract::Currently, it is clear that primary hypertension begins in childhood and that it contributes to the early development of chronic kidney disease (CKD). Hypertension also increases the risk of cardiovascular morbidity and mortality, and that risk rises as blood pressure levels escalate. As among adult patients, overweig...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-012-0333-5
更新日期:2012-10-01 00:00:00
abstract::Congenital heart defects (CHD) are the third leading cause of death in children <1 year of age in Mexico where there is a high prevalence of the 677C → T polymorphism of the MTHFR gene. This is important because the homozygous 677T/T MTHFR gene and deficiency of folic acid (FA) intake have been associated with CHD. Ou...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0380-y
更新日期:2013-01-01 00:00:00
abstract::Acute kidney injury (AKI) is a potential complication for children with congenital heart disease (CHD) after cardiopulmonary bypass (CPB) surgery. This study was designed to investigate and compare the predictive values of urinary biomarkers for AKI after CPB surgery in infants and young children and to determine the ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0563-6
更新日期:2013-04-01 00:00:00
abstract::Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present prospective, obser...
journal_title:Pediatric cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00246-019-02215-y
更新日期:2019-12-01 00:00:00
abstract::This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8 kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlant...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00246-014-0905-7
更新日期:2014-10-01 00:00:00
abstract::Circulating progenitor cells have been extensively studied in the context of heart disease in adults. In these patients, they have been demonstrated to be markers of myocardial injury and recovery as well as potential therapeutic agents. However, studies in children are much more limited. Here we review current knowle...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-015-1300-8
更新日期:2016-02-01 00:00:00
abstract::Very young mammals have an impressive cardiac regeneration capacity. In contrast, cardiac regeneration is very limited in adult humans. The hearts of young children have a higher regenerative capacity compared with adults, as, for example, seen after surgical correction of an anomalous left coronary artery arising fro...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-015-1120-x
更新日期:2015-04-01 00:00:00
abstract::This study was undertaken to examine the impact that prenatal diagnosis of congenital heart disease (CHD) has on birth and early neonatal outcomes. The prevalence of prenatally diagnosed CHD has risen over the past decade, but the effect that prenatal diagnosis of CHD has on peripartum decisions remains unclear. No co...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0504-4
更新日期:2013-03-01 00:00:00
abstract::The response to warfarin is highly variable among individuals and such variability is likely to have some genetic basis. We evaluted the effect of VKORC1 polymorphisms on warfarin response among Japanese, taking advantage of its unique population structure in which CYP2C9 *2 and *3 alleles are relatively rare. Thirty-...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-1150-x
更新日期:2006-11-01 00:00:00
abstract::The single right ventricle (RV) in hypoplastic left heart syndrome (HLHS) often develops systolic dysfunction with time and this affects prognosis. Mechanical dyssynchrony has been reported in HLHS but has not consistently correlated with systolic function or electrical dyssynchrony. The aims of this study were to ass...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02091-6
更新日期:2019-06-01 00:00:00
abstract::Ductal stenting (DS) palliates duct-dependent lesions using coronary stents. Sirolimus-eluting stents have replaced bare-metal stents in coronary interventions. Concerns exist about sirolimus levels in neonates. Therapeutic immunosuppressive sirolimus level is 5-15 ng/ml. After neonatal DS, drug levels were assessed a...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02381-4
更新日期:2020-10-01 00:00:00
abstract::We studied the safety and efficacy of closing patent ductus arteriosus by Nit-Occlud coils via retrograde approach. This is a retrospective study of 46 attempts to close ducts by this method in two hospitals in Egypt and Iran. Ductus arteriosus was crossed by left or right Judkins or endhole catheters. The coil was de...
journal_title:Pediatric cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00246-017-1589-6
更新日期:2017-04-01 00:00:00
abstract::Sinus node disease is a problem encountered in patients after the Mustard surgery, requiring a pacemaker implantation. The knowledge of the complexity anatomy is crucial because of the possible challenges associated with this procedure. We report a case of a 24-year-old woman presented with symptomatic bradycardia, in...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1155-z
更新日期:2015-08-01 00:00:00