Immunosuppressive therapy of chronic myocarditis in children: three cases and the design of a randomized prospective trial of therapy.

Abstract:

:Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone resulted in the normalization of echocardiographic findings. Based on these observations, a randomized, multicenter treatment study of chronic myocarditis in children (TCMC) has been initiated.

journal_name

Pediatr Cardiol

journal_title

Pediatric cardiology

authors

Schmaltz AA,Demel KP,Kallenberg R,Neudorf U,Kandolf R,Klingel K,Bültmann B

doi

10.1007/s002469900292

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

235-9

issue

3

eissn

0172-0643

issn

1432-1971

journal_volume

19

pub_type

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