The multiple faces of carcinoid tumor: performance characteristics of low-grade neuroendocrine carcinoma metastatic to the liver in an educational interlaboratory slide comparison program.

abstract：OBJECTIVES:To determine the prevalence of merosin deficiency in cases of unclassified congenital muscular dystrophy and to determine the temporal stability of merosin epitopes in fixed and stored archival material. MATERIALS AND METHODS:Using an antibody to human merosin we retrospectively studied 12 cases of undiagno...

journal_title：Archives of pathology & laboratory medicine

authors： Brett FM,Loring P,Caesar A,Burke M,Brennan RP,King M,Farrell MA

更新日期：1998-01-01 00:00:00

abstract：CONTEXT:The inhibition of oncogenic kinase signaling is a successful strategy to treat both hematologic and solid malignancies. Patients with chronic myelogenous leukemia, lung adenocarcinoma, renal cell carcinoma, and gastrointestinal stromal tumors are experiencing tremendous clinical benefits from targeted therapies...

journal_title：Archives of pathology & laboratory medicine

authors： Marrari A,Wagner AJ,Hornick JL

更新日期：2012-05-01 00:00:00

abstract：CONTEXT:- Current 2013 World Health Organization classification of tumors of soft tissue arranges these tumors into 12 groups according to their histogenesis. Tumor behavior is classified as benign, intermediate (locally aggressive), intermediate (rarely metastasizing), and malignant. In our practice, a general approac...

journal_title：Archives of pathology & laboratory medicine

authors： Wei S,Henderson-Jackson E,Qian X,Bui MM

更新日期：2017-08-01 00:00:00

abstract：:The objective of this study was to evaluate conjunctival nevi for p53 gene mutations. We studied 11 conjunctival nevi by immunohistochemistry with the DO7 monoclonal p53 antibody as well as the cell proliferation marker, MIB1. Of the 11 cases, 2 were negative, 2 had less than 1%, and 7 had more than 2% p53 immunoposit...

journal_title：Archives of pathology & laboratory medicine

authors： Jay V,Ho M,Hunter W,Rootman D,Zielenska M

更新日期：1996-04-01 00:00:00

abstract：CONTEXT:Implementation of proficiency testing for gynecologic cytology was delayed 20 years because of challenges addressing the subjective nature of cytologic interpretation and replicating normal working conditions. Concern remains regarding test scoring, slide validation, test environment, and other issues. How thes...

journal_title：Archives of pathology & laboratory medicine

authors： Howell LP,Nayar R,Savaloja L,Tabbara S,Thomas N,Winkler B,Tworek J

更新日期：2013-02-01 00:00:00

abstract：CONTEXT:Workup for prolonged prothrombin time (PT) and activated partial thromboplastin time (PTT) is a frequent referral to a Hematology and Coagulation Laboratory. Although the workup should be performed in a timely and cost-effective manner, the complete laboratory assessment of the coagulation state has not been st...

journal_title：Archives of pathology & laboratory medicine

authors： Acosta M,Edwards R,Jaffee IM,Yee DL,Mahoney DH,Teruya J

更新日期：2005-08-01 00:00:00

abstract：CONTEXT:Despite the widespread practice of pathologist review of blood and body fluid smears, little is known about its impact on improving patient care. OBJECTIVE:To assess the clinical usefulness of pathologist review of blood and body fluid smears. DESIGN:Survey study. Pathology residents contacted the ordering ph...

journal_title：Archives of pathology & laboratory medicine

authors： Sandhaus LM,Wald DN,Sauder KJ,Steele EL,Meyerson HJ

更新日期：2007-03-01 00:00:00

abstract：:Blood banks and transfusion services should anticipate that patients contracting transfusion-transmitted diseases will claim that these facilities have a duty to warn or notify patients of potential transfusion risks. Although physicians treating patients must secure informed consent by describing significant risks an...

journal_title：Archives of pathology & laboratory medicine

authors： Willett DE

更新日期：1989-03-01 00:00:00

abstract：:A 38-year-old woman suffered rapid onset of renal failure between 11 and 15 months after undergoing a jejunoileal bypass for morbid obesity. Microscopic examination of renal biopsy specimens revealed oxalosis and severe tubulointerstitial nephritis. Immunofluorescence microscopy disclosed linear staining of tubular ba...

journal_title：Archives of pathology & laboratory medicine

authors： Zawada ET Jr,Johnston WH,Bergstein J

更新日期：1981-07-01 00:00:00

abstract：CONTEXT:More than 25 years ago, John G. Azzopardi described a distinctive intraepithelial neoplastic breast lesion, which he designated "clinging carcinoma in situ"; he considered it as another variant of ductal carcinoma in situ, an early lesion that can easily be missed because the changes are mainly cytologic rather...

journal_title：Archives of pathology & laboratory medicine

authors： Moinfar F

更新日期：2009-06-01 00:00:00

abstract：:We report a case of solitary fibrous tumor involving the spinal nerve root at the L1-L2 level in a 67-year-old man. The patient presented with lumbar pain and weakness in his right lower extremity. Histologically, the tumor was composed of a proliferation of monomorphous spindle cells in an abundant collagenous stroma...

journal_title：Archives of pathology & laboratory medicine

authors： Piana S,Putrino I,Cavazza A,Nigrisoli E

更新日期：2004-03-01 00:00:00

abstract：CONTEXT:- The Ki-67 index is strongly prognostic and is used as a surrogate marker to distinguish luminal A from luminal B breast cancer types. OBJECTIVE:- To investigate differences in Ki-67 index between core needle biopsy samples and matched surgical samples in breast cancer. DESIGN:- We included patients with inv...

journal_title：Archives of pathology & laboratory medicine

authors： Ahn S,Lee J,Cho MS,Park S,Sung SH

更新日期：2018-03-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a neoplastic proliferation of Langerhans cells that occurs in a range of nodal and extranodal sites. Scattered reports of LCH within the thymus exist, typically among children within the setting of multifocal, multisystem disease. Rare cases of isolated LCH involving the thymus h...

journal_title：Archives of pathology & laboratory medicine

authors： Lee BH,George S,Kutok JL

更新日期：2003-07-01 00:00:00

abstract：:A causal role of coronary thrombosis in evolving myocardial infarction is now widely accepted. Patients recovering from an acute heart attack have a higher risk of dying, or suffering another infarction, than an age-matched non-coronary population. Thrombosis plays a major part in this additional mortality and morbidi...

journal_title：Archives of pathology & laboratory medicine

authors： Smith P

更新日期：1993-01-01 00:00:00

abstract：:Calbindin-D28k is a highly conserved 28,000 (dalton) molecular-weight (Mr) calcium binding protein with broad tissue distribution, yet cell-type-specific expression predominantly in subpopulations of central and peripheral nervous system neurons, distal tubular cells of the kidney, and enteric neuroendocrine cells. A ...

journal_title：Archives of pathology & laboratory medicine

authors： Katsetos CD,Jami MM,Krishna L,Jackson R,Patchefsky AS,Cooper HS

更新日期：1994-06-01 00:00:00

abstract：:Perfluorochemicals have been shown to have a high affinity for oxygen and therefore, have potential use in circumstances in which conventional blood transfusions are not possible. We examined by light and electron microscopy (EM) histologic changes in liver, spleen, lung, and kidney of rabbits each infused with 20 to ...

journal_title：Archives of pathology & laboratory medicine

authors： Nanney L,Fink LM,Virmani R

更新日期：1984-08-01 00:00:00

abstract：:The salivary glands, despite their relatively simple morphology, give rise to more than 30 histologically distinct benign and malignant tumors. Salivary gland neoplasms comprise less than 2% of all tumors in humans and 3% of all head and neck tumors. They arise in the parotid gland in 80% of cases, and approximately 8...

journal_title：Archives of pathology & laboratory medicine

authors： Schneider M,Rizzardi C

更新日期：2008-02-01 00:00:00

abstract：CONTEXT:Recent changes in pathology residency education have included a decrease in the program length (from 5 years to 4 years for combined anatomic and clinical pathology training) and a national mandate for programs to assess 6 general competencies of trainees. These have undoubtedly led to changes in program curric...

journal_title：Archives of pathology & laboratory medicine

authors： Lagwinski N,Hunt JL

更新日期：2009-09-01 00:00:00

abstract：CONTEXT:Although much has been said and written about medical error and about error in pathology since the publication of the Institute of Medicine's report on medical error in 1999, precise definitions of what constitutes error in anatomic pathology do not exist for the specialty. Without better definitions, it is imp...

journal_title：Archives of pathology & laboratory medicine

authors： Sirota RL

更新日期：2006-05-01 00:00:00

abstract：:Invasive lobular carcinoma of the breast is a relatively common diagnosis. However, other carcinomatous as well as noncarcinomatous neoplasms, either primary or metastatic to the breast, may mimic invasive lobular carcinoma. As treatment may differ, establishing the correct diagnosis is paramount to providing the appr...

journal_title：Archives of pathology & laboratory medicine

authors： Ishikawa MK,Pinsky RW,Smith LB,Jorns JM

更新日期：2015-10-01 00:00:00

abstract：:The blood supply to the upper ventricular septum in the region of the conduction system is more abundant than the literature suggests. I found a significant arterial contribution to the upper ventricular septum from the proximal segment of the right coronary artery (RCA), or one of its early branches, in 77% of 65 hea...

journal_title：Archives of pathology & laboratory medicine

authors： Taylor JR

更新日期：1980-11-01 00:00:00

abstract：:A 50-year-old man presented with a lung mass in the left upper lobe, which was shown by electron microscopy to be a thymoma. There was no evidence of a mediastinal mass. The lymphocytes of the tumor reacted with monoclonal antibody T101, a pan T-cell marker, and with OKT8. B1 and B2 surface antigens characteristic of ...

journal_title：Archives of pathology & laboratory medicine

authors： Green WR,Pressoir R,Gumbs RV,Warner O,Naab T,Qayumi M

更新日期：1987-11-01 00:00:00

abstract：CONTEXT:- Lobular carcinoma in situ (LCIS) refers to a neoplastic proliferation of cells that characteristically shows loss of E-cadherin expression and has long been regarded as a risk factor for invasive breast cancer. Long-term outcome studies and molecular data have also implicated LCIS as a nonobligate precursor t...

journal_title：Archives of pathology & laboratory medicine

authors： Ginter PS,D'Alfonso TM

更新日期：2017-12-01 00:00:00

abstract：:The risks of homologous blood transfusion have motivated some blood centers and private industry to consider providing long-term storage of frozen, autologous red blood cells as a service. The usefulness of this practice is unknown. We performed a retrospective analysis of frozen autologous red blood cell use in two h...

journal_title：Archives of pathology & laboratory medicine

authors： DePalma L,Palmer R,Leitman SF,Dolan WD,Klein HG

更新日期：1990-05-01 00:00:00

abstract：:Primitive neuroectodermal tumors occur most frequently in bone and soft tissue but have been reported in other locations. Primary lung primitive neuroectodermal tumors without pleural or chest wall involvement are extremely rare. We present a case with immunohistochemical and ultrastructural studies and follow-up of t...

journal_title：Archives of pathology & laboratory medicine

authors： Kahn AG,Avagnina A,Nazar J,Elsner B

更新日期：2001-03-01 00:00:00

abstract：:Groove pancreatitis is an uncommon, yet well-described, type of focal chronic pancreatitis, affecting "the groove"-the area between the head of the pancreas, the duodenum, and the common bile duct. Men aged 40 to 50 years are most commonly affected, with a history of alcohol abuse frequently disclosed. Clinical manife...

journal_title：Archives of pathology & laboratory medicine

authors： DeSouza K,Nodit L

更新日期：2015-03-01 00:00:00

abstract：:Human leukocyte antigen typing is currently being done by both serologic and cellular techniques. It is this methodology that forms the basis for organ transplantation, since HLA antigens are the major proteins involved in graft rejection. Matching organ graft donors with recipients at these polymorphic HLA loci clear...

journal_title：Archives of pathology & laboratory medicine

authors： Freeman SM,Noreen HJ,Bach FH

更新日期：1988-01-01 00:00:00

abstract：CONTEXT:Malignancies of the salivary gland are uncommon and account for 0.3% of all malignancies. In addition to their rarity, diagnosing these tumors can be challenging given the histologic overlap among various subtypes, their morphologic heterogeneity, and the recent recognition of new entities. OBJECTIVE:To provid...

journal_title：Archives of pathology & laboratory medicine

authors： McHugh JB,Visscher DW,Barnes EL

更新日期：2009-11-01 00:00:00

abstract：:We studied the use of stat (ie, statim--as soon as possible) laboratory tests at a university teaching hospital. For the 20 most frequently performed tests, 35.7% of the determinations were performed on a stat basis. The frequency with which a test was ordered on a stat basis ranged from 6.0% (for ESR) to 61.5% (amyla...

journal_title：Archives of pathology & laboratory medicine

authors： Chu RC,Williams SV,Eisenberg JM

更新日期：1982-12-01 00:00:00

abstract：CONTEXT:We recently described a patient with chronic lymphocytic leukemia who presented with a breast carcinoma that stained positive for CD5 using a commercially available antibody (CD5-4C7, Novocastra, Newcastle upon Tyne, UK). OBJECTIVES:To study the distribution of CD5 immunoreactivity in tissue sections of a vari...

journal_title：Archives of pathology & laboratory medicine

authors： Walsh R,Peston D,Shousha S

更新日期：2001-06-01 00:00:00