Abstract：
:Primitive neuroectodermal tumors occur most frequently in bone and soft tissue but have been reported in other locations. Primary lung primitive neuroectodermal tumors without pleural or chest wall involvement are extremely rare. We present a case with immunohistochemical and ultrastructural studies and follow-up of the patient. An 18-year-old man presented with hemoptysis. Chest radiographs revealed a right middle lobe mass, and bronchoscopy showed an endobronchial tumor. The lesion was resected by middle lobectomy. After 2 years, a local recurrence was treated by pneumonectomy. The patient died after surgery. Histologically, the tumor was composed of uniform cells with round nuclei and scanty cytoplasm arranged in cohesive lobules with occasional rosette formation. Immunohistochemically, the tumor was positive for vimentin, CD99, neuron-specific enolase, and neurofilaments. Ultrastructural study revealed neurosecretory granules and cytoplasmic processes. Our case shows the value of immunohistochemistry and electron microscopy in the diagnosis of primitive neuroectodermal tumors in unusual locations.
journal_name
Arch Pathol Lab Medjournal_title
Archives of pathology & laboratory medicineauthors
Kahn AG,Avagnina A,Nazar J,Elsner Bdoi
10.1043/0003-9985(2001)125<0397:PNTOTL>2.0.CO;2subject
Has Abstractpub_date
2001-03-01 00:00:00pages
397-9issue
3eissn
0003-9985issn
1543-2165journal_volume
125pub_type
杂志文章abstract：CONTEXT.—:The incidence of anal cancer in the United States is on the rise in high-risk populations. The anal Papanicolaou test (APT) is advocated as a screening tool, in addition to digital rectal examination and high-resolution anoscopy. OBJECTIVE.—:To review our experience and the current literature to create, in c...
journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
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更新日期：1990-12-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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更新日期：1990-02-01 00:00:00
abstract：CONTEXT:Micropapillary urothelial carcinoma (MPUC) is a known aggressive variant of urothelial carcinoma. However, the reasons for its aggressiveness remain unclear. OBJECTIVE:To investigate the frequency of lymphovascular invasion in 22 cases of MPUC. DESIGN:Consecutive tissue sections were stained with D2-40 and CD...
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journal_title：Archives of pathology & laboratory medicine
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更新日期：1978-06-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1043/0003-9985(2003)127
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
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pub_type： 杂志文章,评审
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journal_title：Archives of pathology & laboratory medicine
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更新日期：1991-02-01 00:00:00
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更新日期：1991-05-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1989-02-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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更新日期：1994-12-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1989-01-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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更新日期：1981-10-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1989-08-01 00:00:00
