Abstract:
OBJECTIVE:Corticosteroid injection into the carpal tunnel is frequently used for the treatment of carpal tunnel syndrome (CTS). Steroids are usually mixed with local anesthetics, which have positive effects that can aid the treatment of CTS by inhibiting the spontaneous discharge ability of excitable cells. The aim of this study was 3-fold: (1) to determine the efficacy of triamcinolone acetonide injection in the treatment of CTS, (2) to determine the efficacy of procaine hydrochloride (HCl) in the treatment of CTS, and (3) to compare the efficacy of triamcinolone acetonide and that of procaine HCl in the treatment of CTS. DESIGN:This prospective, randomized, double-blind clinical trial included 99 patients (120 median nerves) with clinical and electrophysiologic evidence of CTS. The 120 median nerves were randomly assigned to one of three groups: group 1 received 40 mg of triamcinolone acetonide, group 2 received 4 ml of 1% procaine HCl, and group 3 received both 40 mg of triamcinolone acetonide and 4 ml of 1% procaine HCl. Clinical and electrophysiologic evaluations were performed at the study onset and at 2 and 6 mos after treatment. RESULTS:At the study onset, there were no statistically significant differences between the groups with respect to distal motor latency, compound motor action potential, compound sensory action potential, sensory nerve conduction velocity, or visual analog scale score; however, distal motor latency, compound sensory action potential amplitude, sensory nerve conduction velocity, and visual analog scale scores improved significantly in each group 2 mos after treatment (P < 0.05), and these improvements persisted at 6 mos after treatment (P < 0.05). Significant differences were not observed between groups 1 and 2 or between groups 1 and 3 with respect to electrophysiologic findings at baseline or 2 or 6 mos after treatment (P > 0.05). Group 3 had better compound sensory action potential amplitude and sensory nerve conduction velocity scores than group 2 did at 6 mos (P < 0.05) and better visual analog scale scores than group 2 did at 2 and 6 mos (P < 0.05). CONCLUSIONS:Local procaine HCl injection and steroid injection effectively reduced the symptoms of CTS and equally improved electrophysiologic findings. As such, procaine HCl can be used in CTS patients in whom steroid use is contraindicated.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
Karadaş O,Tok F,Ulaş UH,Odabaşi Zdoi
10.1097/PHM.0b013e31820639ecsubject
Has Abstractpub_date
2011-04-01 00:00:00pages
287-92issue
4eissn
0894-9115issn
1537-7385journal_volume
90pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:The aim of this study was to examine the impact of demographics, preexisting medical conditions, and in-hospital complications of COVID-19 infection on functional status at discharge. DESIGN AND PARTICIPANTS:A retrospective chart review was conducted on 119 patients hospitalized for COVID-19 infection betwee...
journal_title:American journal of physical medicine & rehabilitation
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doi:10.1097/PHM.0000000000001614
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
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更新日期:2018-11-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/01.PHM.0000104662.71129.B9
更新日期:2004-01-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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journal_title:American journal of physical medicine & rehabilitation
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更新日期:2006-02-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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更新日期:2010-03-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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更新日期:2002-10-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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更新日期:2008-02-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
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更新日期:2014-03-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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更新日期:2012-11-01 00:00:00