Abstract:
OBJECTIVE:To examine sources of repeat Chlamydia trachomatis infections using behavioural and molecular methods. METHODS:Women with C. trachomatis had baseline and 4-month follow-up visits consisting of behavioural surveys and genotyping of C. trachomatis. Frequencies and population-attributable risk percentages (PAR%) were estimated for possible sources of repeat infections including sex partners not known to be treated, new sex partners, and sex partners not known to be monogamous. Women with different genotypes at baseline and follow-up were classified as different partner sources of infection. RESULTS:The cumulative incidence of repeat infections in the sample (n=183) was 13% (95% CI 8% to 18%). Predictors of repeat infections included younger age and continued sex with a partner not known to be treated. Frequencies of having partners not known to be treated, new partners, or partners not known to be monogamous at follow-up were 21% (95% CI 15% to 27%), 37% (95% CI 30% to 44%) and 33% (95% CI 28% to 41%), respectively. The PAR% for having a partner not known to be treated was 26% (95% CI 3% to 49%) and for having a new sex partner was 21% (95% CI 0% to 50%). Among eight patients with available genotypes at baseline and follow-up, five had different genotypes and were classified as having a different partner source of infection. CONCLUSIONS:Different sex partner sources of repeat C. trachomatis infections other than untreated sex partners may contribute substantially to the burden of repeat infections.
journal_name
Sex Transm Infectjournal_title
Sexually transmitted infectionsauthors
Niccolai LM,Livingston KA,Laufer AS,Pettigrew MMdoi
10.1136/sti.2010.045484subject
Has Abstractpub_date
2011-04-01 00:00:00pages
248-53issue
3eissn
1368-4973issn
1472-3263pii
sti.2010.045484journal_volume
87pub_type
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journal_title:Sexually transmitted infections
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journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
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doi:10.1136/sextrans-2012-050506
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pub_type: 杂志文章
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journal_title:Sexually transmitted infections
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doi:10.1136/sextrans-2011-050236
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journal_title:Sexually transmitted infections
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doi:10.1136/sti.2005.016667
更新日期:2006-04-01 00:00:00
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journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
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journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
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更新日期:2010-06-01 00:00:00
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更新日期:2013-11-01 00:00:00
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更新日期:1999-10-01 00:00:00
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journal_title:Sexually transmitted infections
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更新日期:2013-09-01 00:00:00
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journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.suppl_1.i176
更新日期:2002-04-01 00:00:00
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journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2009.037572
更新日期:2010-02-01 00:00:00
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journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
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更新日期:2008-06-01 00:00:00
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doi:10.1136/sextrans-2020-054428
更新日期:2020-09-03 00:00:00
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pub_type: 杂志文章
doi:10.1136/sextrans-2011-050455
更新日期:2013-02-01 00:00:00
abstract::The distribution of HIV-1 subtypes in a population tracks the spread and evolution of the epidemic. This study is a systematic review of all available evidence on HIV-1 molecular epidemiology and subtype distribution in the Middle East and North Africa. Sources of data included Medline and various institutional docume...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sti.2010.043711
更新日期:2011-03-01 00:00:00