Hnrnpk, a protein differentially expressed in immature rat ovarian development, is required for normal primordial follicle assembly and development.

abstract：:Testicular peritubular cells are myofibroblastic cells, which represent the major cellular components of the wall of the seminiferous tubules. In men their phenotypic characteristics, including possible secretory activity and regulation, are not well known, in neither normal nor pathologically altered testes. Especial...

journal_title：Endocrinology

authors： Schell C,Albrecht M,Mayer C,Schwarzer JU,Frungieri MB,Mayerhofer A

更新日期：2008-04-01 00:00:00

abstract：:Physiological roles for PTH-related peptide (PTHrP) appear varied, but remain to be clarified. The peptide is present in large amounts in milk, and PTHrP mRNA has been shown to be present in high amounts in lactating mammary gland. Because PTHrP can cause smooth muscle relaxation, we hypothesized that the peptide migh...

journal_title：Endocrinology

authors： Seitz PK,Cooper KM,Ives KL,Ishizuka J,Townsend CM Jr,Rajaraman S,Cooper CW

更新日期：1993-09-01 00:00:00

abstract：:We examined the levels and stability of glucocorticoid receptor activity in cytosol preparations of rat lung and other tissues. [3H]Dexamethasome binding capacity at 2 C in lung cytosol decreases with a t1/2 of 40 min in the absence of steroid or a sulfhydryl compound. This rapid inactivation of unbound receptor is pr...

journal_title：Endocrinology

authors： Granberg JP,Ballard PL

更新日期：1977-04-01 00:00:00

abstract：:The effect of progesterone on the secretion of LH was studied in intact and castrated immature female sheep between 12 and 42 weeks of age. (First spontaneous ovulation occurs between 30 and 50 weeks of age.) Progesterone was administered by means of Silastic capsules inserted SC to achieve circulating progesterone co...

journal_title：Endocrinology

authors： Foster DL,Karsch FJ

更新日期：1976-07-01 00:00:00

abstract：:We examined the gene expression of V-1, a novel soluble protein with the cdc10/SWI6 motif, in pseudopregnant rat ovaries. Northern blot analysis on days 1, 5, and 11 of pseudopregnancy revealed an approximately 2-fold increase in the V-1 messenger RNA (mRNA) expression level on day 5 to that on day 1, and no significa...

journal_title：Endocrinology

authors： Song SY,Asakai R,Kenmotsu N,Taoka M,Isobe T,Yamakuni T

更新日期：1996-04-01 00:00:00

abstract：:Cultured pineal ependymal cells from rat fetuses aged 17 to 19 days post-coitum release into their media a substance that has hydroosmotic, antidiuretic and rat uterine activities. Paper chromatography of concentrates from culture media demonstrates that the substance possessing all the above activities was eluted fro...

journal_title：Endocrinology

authors： Pavel S,Goldstein R,Ghinea E,Calb M

更新日期：1977-01-01 00:00:00

abstract：:Experiments were performed in vitro to examine the possible role of calcium and calmodulin in GRF-induced somatostatin (SRIF) release from the median eminence. Adult male rats were used as tissue donors. The median eminences were first prestimulated in 0.4 ml Krebs Ringer bicarbonate glucose buffer (pH 7.4) containing...

journal_title：Endocrinology

authors： Aguila MC,McCann SM

更新日期：1988-07-01 00:00:00

abstract：:The regulation of GRF secretion was studied using a fetal rat hypothalamic cell culture system. The cells were subjected to short term release experiments on days 10-18 after plating, and GRF secretion was assessed by RIA. The identity of GRF immunoreactivity in the incubation medium was confirmed by reverse phase liq...

journal_title：Endocrinology

authors： Baes M,Vale WW

更新日期：1989-01-01 00:00:00

abstract：:We have investigated the activation of ERK2, a serine/threonine kinase necessary for transmission of mitogenic signals, in cells derived from mouse embryos homozygous for a null mutation of the insulin-like growth factor (IGF)-1R gene (R- cells) and from wild-type littermates (W cells), respectively. Stimulation of qu...

journal_title：Endocrinology

authors： Swantek JL,Baserga R

更新日期：1999-07-01 00:00:00

abstract：:The effect of [D-Trp6]LHRH, a potent agonist of LHRH, on pituitary-testicular responses was investigated in male rhesus monkeys. Acute administration of 5, 25, or 500 micrograms [D-Trp6]LHRH produced dose-related increases in serum testosterone and bioassayable LH levels. The administration of 500 micrograms [D-Trp6]L...

journal_title：Endocrinology

authors： Sundaram K,Connell KG,Bardin CW,Samojlik E,Schally AV

更新日期：1982-04-01 00:00:00

abstract：:Recently, heterogeneity of POMC mRNA content between intermediate lobe melanotropes of the rat pituitary gland was demonstrated by in situ hybridization of tissue sections. In the present study the heterogeneity of POMC mRNA content in dispersed rat pituitary cells has been investigated. Acutely dispersed cells from a...

journal_title：Endocrinology

authors： Hatfield JM,Daikh DI,Adelman JP,Douglass J,Bond CT,Allen RG

更新日期：1989-03-01 00:00:00

abstract：:Rat reticulocytes contain a cytosol activator protein (RCAP) that augments hormone-sensitive adenylate cyclase activity in the rat reticulocyte and other systems. In a previous publication, using a highly purified preparation of RCAP, we reported that the stimulatory guanine nucleotide-binding protein (Ns) was require...

journal_title：Endocrinology

authors： Shane E,Yeh M,Feigin AS,Owens JM,Bilezikian JP

更新日期：1985-07-01 00:00:00

abstract：:The previously reported synchronous oscillations in plasma glucose and insulin levels have been further studied to determine whether the phenomenon can be attributed to cyclic secretion or degradation of the hormone. Plasma C-peptide concentrations were measured and found to cycle with the same period as plasma insuli...

journal_title：Endocrinology

authors： Koerker DJ,Goodner CJ,Hansen BW,Brown AC,Rubenstein AH

更新日期：1978-05-01 00:00:00

abstract：:Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (IGSF1) gene cause central hypothyroidism. IGSF1 is a transmembrane glycoprotein of unknown function expressed in thyrotropin (TSH)-producing thyrotrope cells of the anterior pituitary gland. The protein is cotranslationally cleaved, with ...

journal_title：Endocrinology

authors： Turgeon MO,Silander TL,Doycheva D,Liao XH,Rigden M,Ongaro L,Zhou X,Joustra SD,Wit JM,Wade MG,Heuer H,Refetoff S,Bernard DJ

更新日期：2017-04-01 00:00:00

abstract：:Bovine parathyroid organoids were maintained for up to 12 days of culture in the presence or absence of insulin. Insulin-treated organoids secreted more PTH and secretory protein-I (SP-I) than did untreated organoids at both 1.4 and 1.8 mM Ca, concentrations chosen to promote partially elevated and suppressed secretio...

journal_title：Endocrinology

authors： Hinton DA,MacGregor RR

更新日期：1991-01-01 00:00:00

abstract：:Steroids mediate the gonadotropic stimulus of oocyte maturation in fish and amphibians. Such a role of steroids in mammals has not been confirmed until recently. A series of studies presented data suggesting that steroids might be involved in meiosis of mouse oocytes. Here we examined this suggestion using in vitro cu...

journal_title：Endocrinology

authors： Motola S,Popliker M,Tsafriri A

更新日期：2007-09-01 00:00:00

abstract：:cAMP-dependent protein kinase activity was present in a soluble TSH receptor fraction. The Km of this enzyme was 2.2 X 10(-6) M for casein substrate in the absence or presence of 10(-5) M cAMP. A [3H]cAMP-binding protein was also found in this fraction. The Ka for [3H]cAMP-binding was 0.11 X 10(6) M-1, with a total bi...

journal_title：Endocrinology

authors： Hashizume K,DeGroot LJ

更新日期：1979-06-01 00:00:00

abstract：:Newborn male rats were treated SC with dexamethasone phosphate (100 microgram) or dexamethasone acetate (100 microgram) on postnatal day 1, dexamethasone phosphate (5.0 microgram) opn postnatal days 1, 2, 3, or the corresponding drug vehicle. All animals were sacrificed 65-70 days later at previously determined daily ...

journal_title：Endocrinology

authors： Poland RE,Rubin RT,Weichsel ME Jr

更新日期：1981-03-01 00:00:00

abstract：:After incubation with 0.5 mM isobutylmethylxanthine, 1 microM dexamethasone, and 1 microM insulin for 72 h, 3T3-L1 cells acquire the phenotypic characteristics of mature adipocytes, including a hormone-sensitive particulate cAMP phosphodiesterase activity. In addition, adipocytes contain soluble cAMP and calmodulin-se...

journal_title：Endocrinology

authors： Elks ML,Manganiello VC,Vaughan M

更新日期：1984-10-01 00:00:00

abstract：:Gene expression of fibroblast growth factor-9 (FGF9) is decreased in granulosa cells (GC) of cystic follicles compared with normal dominant follicles in cattle. The objectives of this study were to investigate the effects of FGF9 on GC steroidogenesis, gene expression, and cell proliferation and to determine the hormo...

journal_title：Endocrinology

authors： Schreiber NB,Spicer LJ

更新日期：2012-09-01 00:00:00

abstract：:Our previous work suggests that persistent protein malnutrition in immature domestic fowl (Gallus gallus domesticus) alters ACTH-adrenocortical cell interaction, possibly including ACTH receptors. To investigate this possibility, we measured some ACTH receptor parameters in isolated adrenocortical cells from normal an...

journal_title：Endocrinology

authors： Carsia RV,Weber H

更新日期：1988-02-01 00:00:00

abstract：:Carboxyl-terminal fragments of PTH (C-PTH) appear to have biological properties different from those mediated by the amino-terminal portions of PTH and PTH-related peptide (PTHrP). To characterize a C-PTH receptor that may be involved in mediating these functions, we performed RRAs and affinity cross-linking studies w...

journal_title：Endocrinology

authors： Inomata N,Akiyama M,Kubota N,Jüppner H

更新日期：1995-11-01 00:00:00

abstract：:Regulation of galanin gene expression in the anterior pituitary (AP) is positively influenced by estrogen in rodents and undetermined in humans. The objective of this study was to investigate the mechanism behind estrogen induction of galanin by identifying any putative estrogen receptor (ER) binding sequences within ...

journal_title：Endocrinology

authors： Howard G,Peng L,Hyde JF

更新日期：1997-11-01 00:00:00

abstract：:Thyroid hormones are essential for normal development and metabolism. Thyroid hormone biosynthesis requires iodide uptake into the thyrocytes and efflux into the follicular lumen, where it is organified on selected tyrosyls of thyroglobulin. Uptake of iodide into the thyrocytes is mediated by an intrinsic membrane gly...

journal_title：Endocrinology

authors： Bizhanova A,Kopp P

更新日期：2009-03-01 00:00:00

abstract：:The present study was undertaken to investigate the role of angiotensin II (Ang II) in ovulation and ovarian steroidogenesis and prostaglandin (PG) production via the Ang II receptors in rabbit ovaries. In in vitro perfused rabbit ovaries, PD123319, a selective nonpeptide antagonist for AT2 receptors, reduced the Ang ...

journal_title：Endocrinology

authors： Yoshimura Y,Karube M,Aoki H,Oda T,Koyama N,Nagai A,Akimoto Y,Hirano H,Nakamura Y

更新日期：1996-04-01 00:00:00

abstract：:The effects of rat CRF, arginine vasopressin (VP), oxytocin (OXY), and isoproterenol (ISO) on the biosynthesis and release of pro-ACTH/endorphin-derived peptides by monolayer cultures of rat anterior pituitary cells in complete serum-free medium (CSFM) were studied. When cells were exposed to hormone for 3 h, CRF, VP,...

journal_title：Endocrinology

authors： Wand GS,Eipper BA

更新日期：1987-03-01 00:00:00

abstract：:Changes in insulin, somatostatin, and glucagon secretion during the development of obesity in rats after ventromedial hypothalamic (VMH) lesions were evaluated by measuring fasting hormone levels and their secretion from the isolated perfused pancreas. Fasting peripheral insulin levels were not altered 1 week after th...

journal_title：Endocrinology

authors： Seino Y,Seino S,Takemura J,Tsuda K,Nishi S,Ishida H,Seno M,Usami M,Ikeda M,Imura H

更新日期：1984-02-01 00:00:00

abstract：:The intermediate filament protein nestin was originally found to be expressed in neuronal progenitor cells, but recent studies have shown that other cell types, including endocrine and vascular endothelial cells, express nestin. In the present study, we examined the expression and localization of nestin in the ovaries...

journal_title：Endocrinology

authors： Takahashi N,Itoh MT,Ishizuka B

更新日期：2008-01-01 00:00:00

abstract：:Previous experiments showed that LSH/SsLak female hamsters cease ovarian cyclicity after 2-4 weeks of short photoperiod (SP) treatment. This study was designed to reveal early hormonal and histological changes on day 1 of the estrous cycle (estrus) in SP-treated animals and changes brought about by the SP-induced acyc...

journal_title：Endocrinology

authors： Hauser UE,Benson B

更新日期：1987-01-01 00:00:00

abstract：:The ALP1 [aci-reductone dioxygenase (ARD)-like protein 1] gene was identified in a comprehensive cDNA subtraction aimed at identifying genes regulated by androgens in the rat ventral prostate. ALP1 is homologous to the ARD/ARD' that were discovered in Klebsiella pneumoniae as enzymes that have the same polypeptide seq...

journal_title：Endocrinology

authors： Oram S,Jiang F,Cai X,Haleem R,Dincer Z,Wang Z

更新日期：2004-04-01 00:00:00