Abstract:
:Cysticercosis caused by infection with embryonated eggs of the pork tapeworm Taenia solium is an important cause of neurological disease worldwide. Based on the phylogenetic analysis of mitochondrial DNA, the pathogen has been divided into two geographic clades, corresponding to Afro-American and Asian genotypes. In this study the genotyping of T. solium was carried out by using the nuclear DNA sequences of the immunodiagnostic antigen genes Ag1V1 and Ag2. The two geographic genotypes were supported by the Ag2 sequences, especially showing unique substitutions in each of the genotypes. It seems likely that the Ag2 may be a novel nuclear DNA marker to distinguish the two geographic genotypes of T. solium.
journal_name
Parasitol Intjournal_title
Parasitology internationalauthors
Sato MO,Sako Y,Nakao M,Wandra T,Nakaya K,Yanagida T,Ito Adoi
10.1016/j.parint.2010.11.004subject
Has Abstractpub_date
2011-01-01 00:00:00pages
108-10issue
1eissn
1383-5769issn
1873-0329pii
S1383-5769(10)00178-9journal_volume
60pub_type
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