Abstract：
:In an open study the acceptability of a newly designed vaginal ring was evaluated. The ring, being developed for contraceptive purposes, was made of Silastic and did not contain any medication. Three groups of 10 healthy female volunteers were selected after informed consent. The 6 nulliparous and 24 parous women were equally distributed over the 3 groups. The volunteers were instructed to insert the ring as high in the vagina as possible. In each group a ring of a different stiffness was used for 3 cycles. The first cycle started with the insertion of the ring on day 5 of the menstrual cycle or on the day oral contraception was started. Each cycle consisted of 21 days of vaginal ring use, followed by a 7-day ring-free interval. Expulsions, reasons for removal and complaints were recorded. Vaginal cultures were obtained before insertion and after the third cycle. The vaginal ring was well accepted. There were no differences between the three groups of women using rings of different stiffness. Twenty-two women completed all 3 cycles. Four women (3 nulliparous) stopped after one day. One of the nulliparous women who stopped after one day complained of expulsions, the only one in the study. The 4 women who stopped after a longer period were all parous. In the first cycle several women complained of vaginal discharge, coital problems or foreign body feeling. The complaints decreased in the second cycle and almost disappeared in the third. The rings had no influence on the vaginal flora.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Roumen F,Dieben T,Assendorp R,Bouckaert Pdoi
10.1016/0010-7824(90)90103-3subject
Has Abstractpub_date
1990-08-01 00:00:00pages
201-7issue
2eissn
0010-7824issn
1879-0518pii
0010-7824(90)90103-3journal_volume
42pub_type
杂志文章相关文献
CONTRACEPTION文献大全abstract：:This article reports the effects of gossypol at the genomic level in rat spermatogenic cells. After gossypol treatment for various times (8, 12, and 19 weeks), the spermatogonial cells were allowed to rest for 2 to 4 weeks. The function of histone H4 gene promoter (H4GP) in the repopulating pachytene spermatocytes (RP...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(95)00139-5
更新日期：1995-08-01 00:00:00
abstract：BACKGROUND:Ethinyl estradiol (EE) and progestins have the ability to alter endothelial function. The type of progestin and the ratio of EE to progestin used in oral contraceptive pills (OCPs) may determine how they affect the arterial vasculature. STUDY DESIGN:In this study, we investigated endothelial function across...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2008.07.025
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:Abortion in Turkey has been legal since 1983 and remains so today. Despite this, in 2012 the Prime Minister declared that, in his opinion, abortion was murder. Since then, there has been growing evidence that abortion access particularly in state hospitals is being restricted, although no new legislation h...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2016.09.009
更新日期：2017-02-01 00:00:00
abstract：:The presence of medical conditions that might affect the use of depot-medroxyprogesterone acetate (DMPA) as a contraceptive method was assessed in a rural district in Nepal. A general health survey was conducted in nonpregnant and noncontracepting women aged 15-44 years to determine the presence of any health problems...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(99)00056-6
更新日期：1999-07-01 00:00:00
abstract：:The separate effect of ethinylestradiol (4 micrograms/kg b.w./day) and d-norgestrel (20 micrograms/kg b.w./day) on the fibrinolytic activity in plasma and in vessel walls of the hind leg was investigated in an experimental study on rats. No hormonal effect on the fibrinolytic activity in plasma was registered. However...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(84)90101-x
更新日期：1984-08-01 00:00:00
abstract：:This report provides specific information on the prevalence rates of the most common side effects during the first 3 cycles of use of 3 combination oral contraceptives (OCs) containing 50 mcg estrogen. The probabilities of a symptom occurring for the first time, or persisting once present, during the initial cycles of...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0010-7824(79)90050-7
更新日期：1979-11-01 00:00:00
abstract：:Gossypol, a polyphenolic pigment found in cotton plants, has been implicated as an antifertility agent. This pigment has been shown to alter myriad metabolic pathways. The objective of this study was to determine the effect of gossypol acetic acid on the hepatic microsomal drug metabolizing enzyme system in adult fema...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(90)90009-k
更新日期：1990-12-01 00:00:00
abstract：:Menstrual induction refers to early uterine evacuation without laboratory confirmation of pregnancy in women with delayed menses. Mechanical aspiration is the method used in many countries but, as suggested by a pilot study, mifepristone followed by a prostaglandin analogue could also be effective. We launched the pre...
journal_title：Contraception
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.contraception.2003.09.009
更新日期：2003-12-01 00:00:00
abstract：:Medically induced abortion using a new regimen of oral mifepristone 600 mg and vaginal misoprostol 800 micrograms (PGE1 analogue) was carried out in 100 women. Abortion occurred in all patients without resort to surgery. In 99 women, the abortion occurred within 4 hours of the administration of the prostaglandin. Sixt...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(94)90085-x
更新日期：1994-02-01 00:00:00
abstract：:Two-hundred-eight women attending family planning clinics in New York City who received the Norplant contraceptive system during the first sixteen months of Norplant implants insertions were evaluated. Within this clinic population, Norplant implants were a popular contraceptive choice and were removed from 64 of the ...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(94)90096-5
更新日期：1994-06-01 00:00:00
abstract：:Cervical secretion from three groups of asymptomatic women, either being oral contraceptive (OC) non-users or users (ethinylestradiol plus desogestrel or levonorgestrel), was tested for its capacity to prevent Chlamydia trachomatis, serotype I, from forming inclusions in cycloheximide-treated McCoy cells. The non-user...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(94)90044-2
更新日期：1994-03-01 00:00:00
abstract：:The efficacy of administering an antibiotic prior to IUD insertion to reduce the risk of introducing an upper genital tract infection during the procedure has not yet been established. Two double-blind randomized studies conducted in Africa comparing a 200 mg prophylactic dose of doxycycline with a placebo did not con...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0010-7824(94)90019-1
更新日期：1994-10-01 00:00:00
abstract：BACKGROUND:Music has served as an auxiliary analgesic in perioperative settings. This study evaluates the impact of intraoperative music added to routine pain control measures during first trimester surgical abortion. STUDY DESIGN:We analyzed data from 101 women randomized to undergo abortion with routine pain control...
journal_title：Contraception
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.contraception.2011.11.017
更新日期：2012-08-01 00:00:00
abstract：:A randomized comparative study between Nova-T and Copper-T-200 was performed simultaneously in Denmark, Finland and Sweden. The results of 741 postmenstrual insertions with Nova-T and 780 with Copper-T are reported. The pregnancy rate of Nova-T was lower in every age and parity group. The pregnancy rate of Copper-T-20...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0010-7824(79)80004-9
更新日期：1979-01-01 00:00:00
abstract：:Changes in the physical characteristics of semen and ultrastructure of the spermatozoa of langur monkeys after vas occlusion with styrene maleic anhydride (SMA), a polymer with pH-lowering action, are reported. Vas occlusion resulted in severe reversible hypospermia. Severe oligospermia was observed in the majority of...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(98)00011-0
更新日期：1998-02-01 00:00:00
abstract：:The treatment outcomes of 956 women undergoing second trimester termination of pregnancy with mifepristone and gemeprost were studied. The median gestational age was 16 weeks (range: 12-24 weeks). All women were treated with 200 mg mifepristone orally, followed 36 h later with 1 mg vaginal gemeprost administered every...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(01)00219-0
更新日期：2001-07-01 00:00:00
abstract：:The present study was designed to evaluate the effectiveness of a once-weekly regimen of GnRH antagonist followed by a progestin as a potential new contraceptive method. On menstrual cycle days 2, 9, 16, and 23 (onset of menses = Day 1) monkeys were divided into two groups: 1) those injected sc with 0.1 mg/kg Nal-Glu ...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(09)91007-1
更新日期：1990-06-01 00:00:00
abstract：:The rheological properties of 4 commercially available contraceptive drug delivery gels and their dilutions with a vaginal fluid simulant were measured. These properties govern the critical functions of spreading and retention of these gels over the vaginal surfaces. Measurements made on Conceptrol, KY Plus, Gynol II,...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(00)00184-0
更新日期：2000-12-01 00:00:00
abstract：:User satisfaction and the physical and psychological effects of five commonly used contraceptive methods were investigated in a population survey among 1466 West German women. The focus was on effects attributed by current and past users to these methods, rather than objectively assessed effects, to shed further light...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/s0010-7824(99)00034-7
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVES:The risk of pregnancy is estimated to be 20 times as high among women who use oral contraception, and 90 times as high among condom users, as among women who use certain long-acting contraceptive methods. We explored the population-level implications of this variation in contraceptive efficacy. STUDY DESIGN...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2016.03.014
更新日期：2016-08-01 00:00:00
abstract：:Patterns of bleeding and plasma concentrations of levonorgestrel, progesterone, estradiol, LH and FSH were studied in ten volunteers who had a levonorgestrel-releasing IUD inserted postmenstrually. The IUD was designed to release 12 microgram/day. All but two of the volunteers ovulated during treatment. The ovulatory ...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(80)90127-4
更新日期：1980-02-01 00:00:00
abstract：:The metabolic and hemostatic effects of two oral contraceptives containing 150 mcg desogestrel and 20 mcg ethinyl-estradiol (EE) (MERCILON) or 30 mcg EE (MARVELON) were compared in order to examine the effect of reducing the EE dose in contraceptive pills. Forty-nine women participated in this randomized study during ...
journal_title：Contraception
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0010-7824(93)90141-s
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:Little is known about the out-of-pocket expenditures and dispensing patterns for oral contraceptive pills (OCPs), factors associated with these outcomes and whether they change over time. STUDY DESIGN:Observational cohort using 1996-2006 Medical Expenditure Panel Surveys. RESULTS:Women spent $16 out-of-poc...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2010.09.013
更新日期：2011-06-01 00:00:00
abstract：:This was a dual-cohort study performed to determine if, by using methotrexate alone, abortions could be induced with fewer side effects, without sacrificing effectiveness and patient satisfaction. The subjects were 358 consecutive patients who requested elective medical termination of pregnancy at < 7 weeks gestation....
journal_title：Contraception
pub_type： 临床试验,杂志文章
doi：10.1016/s0010-7824(98)00146-2
更新日期：1999-01-01 00:00:00
abstract：:Levels of immunoreactive follitropin (FSH), lutropin (LH), estradiol, progesterone, 17-hydroxyprogesterone and 20 alpha-dihydroprogesterone were analyzed in peripheral plasma samples collected daily from 21 normally menstruating women during a pretreatment (control) cycle and during months 2 and 6 of administration of...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/0010-7824(81)90049-4
更新日期：1981-03-01 00:00:00
abstract：:The mechanism of action of intrauterine devices varies from one type of device to another, although the principle of action is the same, namely, to interfere with the physiology of reproduction at the endometrial level. The biochemical changes of the endometrial tissue and the composition of the uterine fluid have bee...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/0010-7824(87)90058-8
更新日期：1987-07-01 00:00:00
abstract：:A structured literature review was undertaken to determine, in the context of early medical abortion, the proportion of women who require analgesia, the predictors of analgesia requirement and the most appropriate analgesia regimen. Studies from different centers show wide variations in analgesia use, but, overall, ar...
journal_title：Contraception
pub_type： 杂志文章,评审
doi：10.1016/j.contraception.2006.03.002
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To describe medroxyprogesterone acetate (MPA) levels among Kenyan depot medroxyprogesterone acetate (DMPA) users in the FEM-PrEP HIV prevention trial, and to compare MPA levels between ARV for HIV prevention (treatment) and placebo groups. STUDY DESIGN:We measured MPA in previously collected plasma samples f...
journal_title：Contraception
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.contraception.2016.03.003
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:Our objective was to explore knowledge, attitudes and beliefs about pregnancy and contraceptive decision-making among reproductive-aged women with cystic fibrosis. STUDY DESIGN:In this qualitative study, we used purposive sampling of reproductive age women enrolled in the Adult Cystic Fibrosis program at Pen...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2019.05.005
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To describe the role of worksite characteristics, job role and abortion stigma in clinical abortion workers' occupational stress. STUDY DESIGN:We recruited nurses, medical assistants and counseling staff who provide abortion care at five hospitals and four freestanding clinics in Massachusetts. Study instrum...
journal_title：Contraception
pub_type： 杂志文章
doi：10.1016/j.contraception.2018.07.003
更新日期：2018-12-01 00:00:00
