Abstract:
:It has been slightly more than a decade since the classic mechanistic paradigm that defined the pathogenesis of mucositis was revised. A five-stage sequence of linked biological events forms the basis for our current understanding of how regimen-related mucosal injury occurs. The first stage is the initiation phase, although the gateway to toxicity has been the least studied. This essay proposes new thoughts on the phase's components, how they might interact, and how they present new opportunities for treatment interventions and mucositis risk prediction.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Sonis STdoi
10.1111/j.1601-0825.2010.01681.xsubject
Has Abstractpub_date
2010-10-01 00:00:00pages
597-600issue
7eissn
1354-523Xissn
1601-0825journal_volume
16pub_type
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