Proton-pump inhibitor as palliative care for chemotherapy-induced gastroesophageal reflux disease in pancreatic cancer patients.

Abstract:

:Relief of adverse events induced by chemotherapy is an important issue for patients, especially those with a poor prognosis, such as with pancreatic cancer. There are no reports of the relationship between gastroesophageal reflux disease (GERD) and chemotherapy, so we investigated the incidence of chemotherapy-induced GERD in patients undergoing treatment with gemcitabine or S-1 for pancreatic cancer and the effect of sodium rabeprazole (RPZ), a proton-pump inhibitor. GERD was diagnosed in 40% of the patients according to the Frequency Scale for Symptoms of GERD score, and RBZ therapy significantly improved their symptoms.

journal_name

J Palliat Med

authors

Uwagawa T,Misawa T,Iida T,Sakamoto T,Gocho T,Wakiyama S,Hirohara S,Yanaga K

doi

10.1089/jpm.2009.0404

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

815-8

issue

7

eissn

1096-6218

issn

1557-7740

journal_volume

13

pub_type

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