Abstract：
:Serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the nervous system. It is characterized by mental status changes, autonomic instability, and neuromuscular hyperactivity. Most reported cases of serotonin syndrome are in patients using multiple serotonergic drugs or who have had considerable exposure to a single serotonin-augmenting drug. Diagnosis is made using the Hunter Serotonin Toxicity Criteria, which require the presence of one of the following classical features or groups of features: spontaneous clonus; inducible clonus with agitation or diaphoresis; ocular clonus with agitation or diaphoresis; tremor and hyperreflexia; or hypertonia, temperature above 100.4 degrees F (38 degrees C), and ocular or inducible clonus. Most cases of serotonin syndrome are mild and may be treated by withdrawal of the offending agent and supportive care. Benzodiazepines may be used to treat agitation and tremor. Cyproheptadine may be used as an antidote. Patients with moderate or severe cases of serotonin syndrome require hospitalization. Critically ill patients may require neuromuscular paralysis, sedation, and intubation. If serotonin syndrome is recognized and complications are managed appropriately, the prognosis is favorable.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Ables AZ,Nagubilli Rsubject
Has Abstractpub_date
2010-05-01 00:00:00pages
1139-42issue
9eissn
0002-838Xissn
1532-0650journal_volume
81pub_type
杂志文章,评审abstract：:Management of a wide variety of musculoskeletal conditions requires the use of a cast or splint. Splints are noncircumferential immobilizers that accommodate swelling. This quality makes splints ideal for the management of a variety of acute musculoskeletal conditions in which swelling is anticipated, such as acute fr...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:Skin laceration repair is an important skill in family medicine. Sutures, tissue adhesives, staples, and skin-closure tapes are options in the outpatient setting. Physicians should be familiar with various suturing techniques, including simple, running, and half-buried mattress (corner) sutures. Although suturing is t...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2008-10-15 00:00:00
abstract：:Left ventricular hypertrophy is more common in hypertensive individuals than in normotensive persons. Its presence in hypertensive patients is associated with an increased incidence of ventricular arrhythmias, myocardial infarction, congestive heart failure, stroke and cardiovascular mortality. Echocardiography is mor...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-08-01 00:00:00
abstract：:Melanoma is an increasingly common malignancy, and it affects a younger population than most cancers. Risk factors for melanoma include white race, sun sensitivity, family history of melanoma, and melanocytic nevi. Sunburn and intermittent sun exposure appear to increase the risk of developing melanoma. The role of po...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2005-07-15 00:00:00
abstract：:Ischemic heart disease is one of the most common disorders managed by family physicians. Stratifying patients according to risk is important early in the course of the disease to identify patients who require invasive (percutaneous or surgical) treatment. Physical examination, clinical history, noninvasive tests and a...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-12-01 00:00:00
abstract：:The ability to properly apply casts and splints is a technical skill easily mastered with practice and an understanding of basic principles. The initial approach to casting and splinting requires a thorough assessment of the injured extremity for proper diagnosis. Once the need for immobilization is ascertained, casti...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Magnetic resonance imaging uses powerful magnetic fields and a radiofrequency pulse to provide a diagnostic image. Physicians must identify patients with metallic internal implants, pacemakers and cochlear implants before MRI scanning to prevent serious injury. Some patients also experience severe anxiety from the con...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Ectopic pregnancy occurs at a rate of 19.7 cases per 1,000 pregnancies in North America and is a leading cause of maternal mortality in the first trimester. Greater awareness of risk factors and improved technology (biochemical markers and ultrasonography) allow ectopic pregnancy to be identified before the developmen...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-02-15 00:00:00
abstract：:Microscopic hematuria, a common finding on routine urinalysis of adults, is clinically significant when three to five red blood cells per high-power field are visible. Etiologies of microscopic hematuria range from incidental causes to life-threatening urinary tract neoplasm. The lack of evidence-based imaging guideli...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2006-05-15 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,meta分析
doi：
更新日期：2001-07-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1997-03-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-02-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2007-02-15 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-09-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:Gastroesophageal reflux is defined as the passage of stomach contents into the esophagus with or without accompanied regurgitation (spitting up) and vomiting. It is a normal physiologic process that occurs throughout the day in infants and less often in children and adolescents. Gastroesophageal reflux disease (GERD) ...
journal_title：American family physician
pub_type： 杂志文章,病人教育讲义
doi：
更新日期：2015-10-15 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2008-04-15 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2010-02-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-08-01 00:00:00
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journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1998-02-15 00:00:00
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journal_title：American family physician
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doi：
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