Insulin resistance in the oral glucose tolerance test--a link with hypertension.

Abstract:

:Insulin resistance was evaluated in 807 middle-aged subjects at a health survey, with use of an index measured in 75 g oral glucose tolerance tests. The mean value of insulin resistance was higher in a hypertensive group than among the normotensives, independent of body mass index, physical activity, smoking sex, age, and thiazide treatment. One-third of the hypertensives had a high resistance value. Another third of the hypertensives, and also about one-third of the normotensives, had a slightly increased resistance. The remaining third of the hypertensives had a normal-low resistance. A high resistance was also independently related to obesity, low physical leisure time activity, and a family history of NIDDM, but not to a family history of hypertension. The statistical analysis implied a sequence of events: low physical activity might cause high resistance, which in turn might cause high blood pressure.

authors

Cederholm J,Wibell L

doi

10.3109/02813439109026582

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

53-7

issue

1

eissn

0281-3432

issn

1502-7724

journal_volume

9

pub_type

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