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Acute human parvovirus B19 infection and nephrotic syndrome in patients with sickle cell disease.

Abstract：

:Acute Human Parvovirus B19 (HPV B19) infection is the major cause of transient red cell aplasia (TRCA) and acute anaemia in patients with sickle cell disease (SCD). We report three cases of patients who developed nephrotic syndrome (NS) with chronic sequelae after initially presenting with HPV B19-associated TRCA. There was no correlation between evidence of HPV B19 infection and impaired renal function in our cohort of adult sickle cell patients. This is consistent with a view that although NS is potentially a rare complication of symptomatic acute HPV B19 infection, exposure to HPV B19 is not associated with an increased risk of renal disease.

journal_name

Br J Haematol

journal_title

British journal of haematology

authors

Quek L,Sharpe C,Dutt N,Height S,Allman M,Awogbade M,Rees DC,Zuckerman M,Thein SL

doi

10.1111/j.1365-2141.2009.08062.x

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

289-91

issue

2

eissn

0007-1048

issn

1365-2141

pii

BJH8062

journal_volume

149

pub_type

杂志文章

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