Normal uptake of F-18 FDG in the testis as assessed by PET/CT in a pediatric study population.

Abstract:

OBJECTIVE:To investigate the correlation between the F-18 FDG uptake in the normal testis as assessed by PET-CT and patient age in a pediatric study population. METHODS:The study population consisted of 22 subjects aged between 9 and 17 years. For these subjects 42 PET-CT scans were available for analysis. The testis was identified on the CT images. Mean standard uptake values and testicular volume were calculated based on manually drawn regions-of-interest over the organ. The correlation between mean SUV and age as well as between testicular volume and age was calculated using Pearson's correlation coefficient. RESULTS:A strong and statistically significant positive correlation between F-18 FDG uptake in the testis and age was documented. The correlation coefficient was 0.406 in the analysis based on 42 PET-CT studies (p = 0.005). The correlation between tracer uptake and age was reassessed based on 22 PET-CT studies including the last recorded PET-CT scan per patient. The correlation coefficient was 0.409 (p = 0.05). In addition, based on 22 PET-CT scans, a strong and statistically significant positive correlation between testicular volume and age was documented (r = 0.67, p < 0.001). CONCLUSION:Whereas it was previously shown that in adult men there was a weak but statistically significant negative correlation between F-18 FDG uptake in the normal testis and age, we found a strong and statistically significant positive correlation in children and teenage boys.

journal_name

Ann Nucl Med

authors

Goethals I,De Vriendt C,Hoste P,Smeets P,Ham H

doi

10.1007/s12149-009-0308-7

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

817-20

issue

9

eissn

0914-7187

issn

1864-6433

journal_volume

23

pub_type

杂志文章
  • PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging.

    abstract::Physiological functions (e.g., cerebral blood flow, glucose metabolism, and neuroreceptor binding) can be investigated as parameters estimated by kinetic modeling using dynamic positron emission tomography (PET) images. Imaging of these physiological parameters, called parametric imaging, can locate the regional distr...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s12149-007-0044-9

    authors: Shidahara M,Ikoma Y,Kershaw J,Kimura Y,Naganawa M,Watabe H

    更新日期:2007-09-01 00:00:00

  • Current status of radioligand therapy and positron-emission tomography with prostate-specific membrane antigen.

    abstract::Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein highly expressed by prostate cancer cells. PSMA-based radioligand therapy (RLT) emerged as a promising therapeutic option for prostate cancer in the early 2000s, and has been clinically validated with great enthusiasm during these past two decad...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s12149-020-01549-5

    authors: Inubushi M,Miura H,Kuji I,Ito K,Minamimoto R

    更新日期:2020-12-01 00:00:00

  • Visual and semi-quantitative analyses of dual-phase breast-specific gamma imaging with Tc-99m-sestamibi in detecting primary breast cancer.

    abstract:OBJECTIVES:Breast cancer is the most common malignancy for females worldwide. This study was to evaluate the application of dual-phase breast-specific gamma imaging (BSGI) in detecting primary breast cancer. METHODS:Seventy-six patients with indeterminate breast lesions that underwent dual-phase BSGI enrolled in this ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-013-0776-7

    authors: Tan H,Jiang L,Gu Y,Xiu Y,Han L,Wu P,Zhang H,Shi H

    更新日期:2014-01-01 00:00:00

  • The reproducibility of deep-inspiration breath-hold (18)F-FDG PET/CT technique in diagnosing various cancers affected by respiratory motion.

    abstract:BACKGROUND:The deep-inspiration breath-hold PET/CT (DIBH PET/CT) technique improves the limitations of diagnosing a lesion located in an area influenced by respiratory motion that results in spatial misregistrations caused by respiration between PET and CT. However, its reproducibility with regard to calculating the ma...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-010-0352-3

    authors: Nagamachi S,Wakamatsu H,Kiyohara S,Fujita S,Futami S,Arita H,Tamura S,Kawai K

    更新日期:2010-04-01 00:00:00

  • Study on the primary visual cortex of visually impaired subjects by means of 123I-IMP SPECT and MRI.

    abstract::We conducted a study of rCBF in the primary visual cortex of visually impaired subjects who have not been subjected to external stimulation for a long period, by means of 123I-IMP SPECT and MRI. The four subjects had lost their sight due to brain tumors (n = 2), glaucoma (n = 1) and trauma (n = 1). 123I-IMP SPECT show...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03164976

    authors: Ishikawa N,Nishijo K,Satou M,Takeda T,Itai Y

    更新日期:1995-05-01 00:00:00

  • A brain uptake study of [1-(11)C]hexanoate in the mouse: the effect of hypoxia, starvation and substrate competition.

    abstract::We evaluated the potential of sodium [1-(11)C]hexanoate (11C-HA) as a radiopharmaceutical with which to assess oxidative metabolism of the brain by PET. 11C-HA, sodium [1-(14)C]acetate and [3H]deoxyglucose were simultaneously injected into mice under control, hypoxic and starving conditions. In the control, the brain ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03165404

    authors: Ishiwata K,Ishii K,Ogawa K,Nozaki T,Senda M

    更新日期:1996-05-01 00:00:00

  • Abnormal retention of 99mTc-TF in a hamster model of cardiomyopathy analyzed by 99mTc-TF and 125I-BMIPP autoradiography.

    abstract:OBJECTIVE:Enhanced washout of 99mTc-tetrofosmin (TF) has been reported in patients with hypertrophic cardiomyopathy (HCM). Here, using quantitative dual-autoradiography, the relationship between TF retention abnormality and metabolism depicted by 125I-BMIPP uptake was investigated quantitatively in a hamster model of c...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02985000

    authors: Thet-Thet-Lwin,Takeda T,Wu J,Tsuchiya Y,Itai Y

    更新日期:2004-05-01 00:00:00

  • Assessment of absolute Tc-99m tetrofosmin retention in the myocardium as an index of myocardial blood flow and coronary flow reserve by gated-SPECT/CT: a feasibility study.

    abstract:OBJECTIVE:Estimation of myocardial blood flow (MBF) and coronary flow reserve (CFR) by SPECT myocardial perfusion imaging (MPI) remains challenging. Our aim was to approximate MBF and CFR by quantifying the absolute Tc-99m tetrofosmin retention in the myocardium via gated-SPECT/CT MPI. METHODS:Tracer retention was cal...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12149-015-0982-6

    authors: Apostolopoulos DJ,Kaspiri A,Spyridonidis T,Patsouras N,Savvopoulos CA,Davlouros P,Vassilakos PJ,Alexopoulos D

    更新日期:2015-08-01 00:00:00

  • Assessment of anatomic relation between pulmonary perfusion and morphology in pulmonary emphysema with breath-hold SPECT-CT fusion images.

    abstract:OBJECTIVE:Anatomic relation between pulmonary perfusion and morphology in pulmonary emphysema was assessed on deep-inspiratory breath-hold (DIBrH) perfusion single-photon emission computed tomography (SPECT)-CT fusion images. METHODS:Subjects were 38 patients with pulmonary emphysema and 11 non-smoker controls, who su...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0137-5

    authors: Suga K,Kawakami Y,Iwanaga H,Hayashi N,Seto A,Matsunaga N

    更新日期:2008-06-01 00:00:00

  • Evaluation of the effects of chemotherapy on brain glucose metabolism in children with Hodgkin's lymphoma.

    abstract:OBJECTIVE:Chemobrain is a recently proposed pathological entity. 18F-FDG PET/CT can show objective abnormalities to explain brain disorders caused by chemotherapy, although no study has investigated these phenomena in children to date. The main objective of the present study was to examine quantitatively the effects of...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-019-01363-8

    authors: Tauty A,Noblet V,Paillard C,Fornecker LM,Namer IJ,Bund C

    更新日期:2019-08-01 00:00:00

  • FDG PET in solitary metastastic/secondary tumor of the kidney: a report of three cases and a review of the relevant literature.

    abstract::Metastatic tumors or secondary lymphoma of the kidney are rare and can often be missed on conventional computed tomography (CT) imaging. On the other hand, many types of metastatic tumor or lymphoma can be detected clearly as hotspots of elevated uptake on FDG PET. However, excreted FDG present in the urinary tract mi...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF02985596

    authors: Kaneta T,Hakamatsuka T,Yamada T,Takase K,Sato A,Higano S,Kinomura S,Fukuda H,Takahashi S,Yamada S

    更新日期:2006-01-01 00:00:00

  • Fluorine-18-fluorodeoxyglucose positron emission tomography for assessment of patients with unresectable recurrent or metastatic lung cancers after CT-guided radiofrequency ablation: preliminary results.

    abstract:OBJECTIVES:We compared the diagnostic value of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) with that of computed tomography (CT) following radiofrequency ablation (RFA) of inoperable recurrent or metastatic cancers in the lung. METHODS:Twelve patients (9 males and 3 females; 5 had recurrent l...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985623

    authors: Okuma T,Okamura T,Matsuoka T,Yamamoto A,Oyama Y,Toyoshima M,Koyama K,Inoue K,Nakamura K,Inoue Y

    更新日期:2006-02-01 00:00:00

  • Assessment of collimators in radium-223 imaging with channelized Hotelling observer: a simulation study.

    abstract:OBJECTIVE:Radium-223 (223Ra) is used in unsealed radionuclide therapy for metastatic bone tumors. The aim of this study is to apply a computational model observer to 223Ra planar images, and to assess the performance of collimators in 223Ra imaging. METHODS:The 223Ra planar images were created via an in-house Monte Ca...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-018-1286-4

    authors: Takahashi A,Baba S,Sasaki M

    更新日期:2018-12-01 00:00:00

  • Assessment of cerebral hemodynamics before and after revascularization in patients with occlusive cerebrovascular disease by means of quantitative IMP-SPECT with double-injection protocol.

    abstract:UNLABELLED:The purpose of this study was to validate a double-injection (DI) method with N-isopropyl-[123I]p-iodoamphetamine (IMP) to measure regional cerebral blood flow (rCBF) twice in a single session of dynamic SPECT and to elucidate a possible role of this method to identify patients with occlusive disease of majo...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02987833

    authors: Ueno M,Nishizawa S,Toyoda H,Shimono T,Miyamoto S,Hashimoto N,Konishi J

    更新日期:2001-06-01 00:00:00

  • The search for consistency in the manufacture of PET radiopharmaceuticals.

    abstract::Nuclear Medicine is the specialty of medical imaging, which utilizes a variety of radionuclides incorporated into specific compounds for diagnostic imaging and therapeutic applications. During recent years, research efforts in this discipline have concentrated on the decay characteristics of particular radionuclides a...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF03164930

    authors: Finn RD

    更新日期:1999-12-01 00:00:00

  • Prognostic value of semi-quantitative tumor uptake on Tc-99m sestamibi breast-specific gamma imaging in invasive ductal breast cancer.

    abstract:OBJECTIVES:This study investigated the prognostic value of preoperative breast-specific gamma imaging (BSGI) uptake measured by a semi-quantitative method in invasive ductal carcinoma (IDC). METHODS:One hundred and sixty-two women with IDC who underwent preoperative BSGI were retrospectively enrolled. The tumor-to-nor...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-015-0977-3

    authors: Yoon HJ,Kim Y,Chang KT,Kim BS

    更新日期:2015-08-01 00:00:00

  • False-positive and true-negative hilar and mediastinal lymph nodes on FDG-PET--radiological-pathological correlation.

    abstract:OBJECTIVE:To compare histological findings of FDG-PET false-positive and true-negative hilar and mediastinal lymph nodes. METHODS:Sixty-seven lymphnode areas in 11 patients who were diagnosed to have N3 lymph nodes by FDG-PET and underwent surgery were histologically examined, and the histopathological findings in fal...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985610

    authors: Shiraki N,Hara M,Ogino H,Shibamoto Y,Iida A,Tamaki T,Murase T,Eimoto T

    更新日期:2004-02-01 00:00:00

  • Cerebral muscarinic acetylcholinergic receptor measurement in Alzheimer's disease patients on 11C-N-methyl-4-piperidyl benzilate--comparison with cerebral blood flow and cerebral glucose metabolism.

    abstract::We studied the cerebral muscarinic acetylcholinergic receptor (mACh-R) by means of 11C-N-methyl-4-piperidyl benzilate (11C-NMPB) and positron emission tomography (PET) in Alzheimer's disease (AD) cases, and the findings were compared with the cerebral blood flow (CBF) and the glucose metabolism (CMRGlc) to evaluate th...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03165414

    authors: Yoshida T,Kuwabara Y,Ichiya Y,Sasaki M,Fukumura T,Ichimiya A,Takita M,Ogomori K,Masuda K

    更新日期:1998-02-01 00:00:00

  • Gallium-67 scintigraphic findings in a patient with breast lymphoma complicated with Sjögren syndrome.

    abstract::We report here a patient with mucosa associated lymphoid tissue (MALT)-lymphoma of the breast complicated with Sjögren syndrome. It is speculated that Ga-67 could accumulate not only in lymphoma lesions but also in benign lymphoproliferative locations of Sjögren syndrome. Gallium-67 scintigraphy might be useful for th...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02987866

    authors: Yoshimura M,Koizumi K,Satani K,Kakizaki D,Kawanishi Y,Ohyashiki K,Abe K

    更新日期:2000-06-01 00:00:00

  • Evaluation of the protective effect of verapamil on reperfusion injury by 111In anticardiac myosin antibody in canine myocardial infarction.

    abstract::We quantitated the protective effect of verapamil on reperfusion injury in canine myocardial infarct using 111In-anticardiac myosin antibody and correlated to the electronmicroscopic findings. Experimental myocardial infarction was performed by one hour occlusion of the anterior descending coronary artery and followed...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03164623

    authors: Chung JK,Lim SM,Lee MC,Koh CS,Lee M,Seo JW

    更新日期:1991-09-01 00:00:00

  • High [18F] 2-fluoro-2-deoxy-D-glucose (FDG) uptake of adrenocortical adenoma showing subclinical Cushing's syndrome.

    abstract::A 48-year-old woman with left adrenal tumor, which showed increased uptake of [18F] 2-fluoro-2-deoxy-D-glucose (FDG) was presented. Her adrenal tumor was incidentally discovered, although she had no remarkable illness, and her blood pressure was normal. Hormonal examination including dexamethason suppression test and ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03006609

    authors: Shimizu A,Oriuchi N,Tsushima Y,Higuchi T,Aoki J,Endo K

    更新日期:2003-07-01 00:00:00

  • A case of inferior vena cava thrombosis and pulmonary embolism secondary to acute exacerbation of chronic pancreatitis: a rare finding in radionuclide venography.

    abstract::A rare case of inferior vena cava (IVC) thrombosis and pulmonary embolism secondary to acute exacerbation of chronic pancreatitis was reported. Radionuclide venography and lung perfusion scintigraphy were performed on a 46-year-old male with acute exacerbation of chronic pancreatitis who complained of mild swelling of...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02993720

    authors: Ohta H,Hachiya T

    更新日期:2002-04-01 00:00:00

  • Usefulness of FDG-PET imaging for the radiotherapy treatment planning of pyothorax-associated lymphoma.

    abstract::Pyothorax-associated lymphoma (PAL) is a non-Hodgkin's lymphoma developing in the pleural cavity after a long-standing history of chronic pyothorax (CP). F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) imaging is a useful modality for determination of disease extent of various malignant tumors, includin...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02985123

    authors: Asakura H,Togami T,Mitani M,Takashima H,Yokoe K,Yamamoto Y,Nishiyama Y,Monden T,Toyama Y,Ohkawa M

    更新日期:2005-12-01 00:00:00

  • Tc-99m depreotide SPECT/CT for lymph node staging of non-small-cell lung cancer.

    abstract:OBJECTIVE:To investigate the potential role of Tc-99m depreotide (Tc-DEPR) in the preoperative lymph node (N) staging of non-small-cell lung cancer (NSCLC). METHODS:Sixty-one patients with NSCLC at the potentially operable stage were enrolled and underwent scintigraphy before surgery (n=56) or mediastinoscopy (n=5). I...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-014-0839-4

    authors: Apostolopoulos DJ,Koletsis EN,Spyridonidis T,Paschali A,Papandrianos N,Stamou E,Vassilakos PJ,Dougenis D

    更新日期:2014-06-01 00:00:00

  • The role of adrenocortical scintigraphy in the evaluation of unilateral incidentally discovered adrenal and juxtaadrenal masses.

    abstract::We reviewed the findings of adrenocortical scintigraphy with 131I-6-beta-iodomethyl-19-norcholesterol (NCL-6-131I) of 39 patients to clarify its role in the evaluation of unilateral adrenal or juxtaadrenal masses incidentally discovered by CT, ultrasonography or plain radiography. Twenty-seven benign adrenal masses sh...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03164960

    authors: Nakajo M,Nakabeppu Y,Yonekura R,Iwashita S,Goto T

    更新日期:1993-08-01 00:00:00

  • Bone scintigraphic and CT evaluation of chondrosarcoma of the rib: correlation with histological grade in 6 cases.

    abstract:OBJECTIVE:The objective of this study is to assess the value of CT and bone scintigraphic findings for grading of rib chondrosarcoma. METHODS:Included in this study were six cases of histologically proven chondrosarcoma of the rib, in which bone scintigraphy and/or CT was performed. Correlation of histologic grade (I-...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02984588

    authors: Ehara S,Nakayama T,Nishida J,Shiraishi H,Yoshioka H,Aoki J

    更新日期:2004-10-01 00:00:00

  • Prognostic role of pretreatment 18F-FDG PET/CT in primary brain lymphoma.

    abstract:OBJECTIVE:Primary brain lymphoma is an aggressive extranodal non-Hodgkin lymphoma with poor prognosis. Many possible prognostic factors are investigated with controversial results, but possible prognostic role of 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) features re...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-018-1274-8

    authors: Albano D,Bertoli M,Battistotti M,Rodella C,Statuto M,Giubbini R,Bertagna F

    更新日期:2018-10-01 00:00:00

  • Usefulness of the Chang attenuation correction method with use of a CT-based μ map by FBP reconstruction in (201)Tl SPECT-MPI.

    abstract:OBJECTIVE:Attenuation correction (AC) on nuclear images of non-uniform domains is generally performed by a change of the computed tomography (CT) values to μ values, which are then inserted as components into the detection probability of iterative reconstruction techniques (OS-EM Iterative AC). We established an AC tec...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-015-0972-8

    authors: Nakamura Y,Tomiguchi S

    更新日期:2015-06-01 00:00:00

  • Attenuation correction using combination of a parallel hole collimator and an uncollimated non-uniform line array source.

    abstract::Attenuation correction is very important for quantitative SPECT imaging. We designed an uncollimated non-uniform line array source (non-uniform LAS) for attenuation correction based on transmission computed tomography (TCT) using Tc-99m and compared its performance with an uncollimated uniform line array source (unifo...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02984481

    authors: Kojima A,Kawanaka K,Nakaura T,Shiraishi S,Utsunomiya D,Katsuda N,Tomiguchi S,Yamashita Y,Matsumoto M,Motomura N,Ichihara T

    更新日期:2004-07-01 00:00:00

  • Micronucleus evaluation for determining the chromosomal breakages after radionuclide synovectomy in patients with hemophilia.

    abstract:OBJECTIVE:To investigate the genotoxic effects of (90)Y and (186)Re in patients with hemophilia who were undergoing radionuclide synovectomy (RS) procedure in the last 3 years. METHODS:Nineteen patients were enrolled in the study. Most of the patients (n = 17) were hemophilia-A (mean age 20.6 ± 10.5 years) and 18 pati...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-011-0540-9

    authors: Kavakli K,Cogulu O,Karaca E,Durmaz B,Ozkinay F,Aydogdu S,Ozkilic H,Balkan C,Karapinar D,Ay Y

    更新日期:2012-01-01 00:00:00