PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging.

abstract：:Bone scintigraphy is often performed to assess the response to systemic therapy of bone metastasis from prostate cancer. We examined the changes in bone scintigraphic findings and the agreement with AIP, AcP, or other tumor markers measured in the follow-up of patients with known bone metastasis after hormonal therapy...

journal_title：Annals of nuclear medicine

authors： Koizumi K,Uchiyama G,Komatsu H

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:The objectives of this study were to (1) elucidate the relationship between the mean CBF in the whole brain (Av.mCBF) before rehabilitation of CVD patients and the BI score before and after rehabilitation, (2) determine whether the efficacy of rehabilitation can be predicted by measurement of the Av.mCBF, and (...

journal_title：Annals of nuclear medicine

authors： Tamamoto F,Sumi Y,Nakanishi A,Okayasu K,Maehara T,Katayama H

更新日期：2000-02-01 00:00:00

abstract：:Attenuation correction is very important for quantitative SPECT imaging. We designed an uncollimated non-uniform line array source (non-uniform LAS) for attenuation correction based on transmission computed tomography (TCT) using Tc-99m and compared its performance with an uncollimated uniform line array source (unifo...

journal_title：Annals of nuclear medicine

authors： Kojima A,Kawanaka K,Nakaura T,Shiraishi S,Utsunomiya D,Katsuda N,Tomiguchi S,Yamashita Y,Matsumoto M,Motomura N,Ichihara T

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:Nitrate administration has been proposed to enhance the detection of myocardial viability when performing myocardial perfusion imaging. In this study, we aimed to compare Tl-201 exercise-rest-reinjection protocol with rest isosorbide dinitrate (ISDN)-Tc99m MIBI study in the same population examined for the myoc...

journal_title：Annals of nuclear medicine

authors： Günel SE,Akgun A

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:The potential of positron emission tomography/computed tomography using 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) (62Cu-ATSM PET/CT), which was originally developed as a hypoxic tracer, to predict therapeutic resistance and prognosis has been reported in various cancers. Our purpose was to investigate pr...

journal_title：Annals of nuclear medicine

authors： Toriihara A,Ohtake M,Tateishi K,Hino-Shishikura A,Yoneyama T,Kitazume Y,Inoue T,Kawahara N,Tateishi U

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Two methods of quantitating cerebral blood flow (CBF) with iodine-123-labeled N-isopropyl-p-iodoamphetamine (I-123 IMP) and a two-compartment model had been proposed; one is the table look-up (TLU) method and the other is the autoradiographic (ARG) method. The TLU method provides values of the cerebral blood ...

journal_title：Annals of nuclear medicine

authors： Inoue K,Ito H,Nakagawa M,Goto R,Yamazaki T,Fukuda H

更新日期：2002-07-01 00:00:00

abstract：:By means of Tc-99m dimercaptosuccinic acid (DMSA) scintigraphy, an established method for assessing renal cortical damage, we evaluated the pick-up rate for renal defects (scars) by single photon computed tomography (SPECT) and planar images of 10 normal volunteers, and 58 patients (70 scintigrams) with upper urinary ...

journal_title：Annals of nuclear medicine

authors： Itoh K,Asano Y,Tsukamoto E,Kato C,Nakada K,Nagao K,Furudate M,Gotoh T,Nonomura K,Koyanagi T

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:We investigated the prevalence and clinical significance of incidental focal 18F-FDG uptake in the frontal process of the maxilla, mimicking malignancy on PET/CT. METHODS:From a total of 32,834 patients who underwent 18F-FDG PET/CT, patients with focal uptake in the frontal process of the maxilla were select...

journal_title：Annals of nuclear medicine

authors： Park SB,Choi JY,Kim HJ,Kim HJ,Lee KH,Kim BT

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Advances in radiopharmaceuticals and clinical understanding have escalated the use of intraoperative gamma probes in surgery. However, most probes on the market are non-imaging gamma probes that suffer from the lack of ancillary information of the surveyed tissue area. We have developed a novel, hand-held di...

journal_title：Annals of nuclear medicine

authors： Singh B,Stack BC Jr,Thacker S,Gaysinskiy V,Bartel T,Lowe V,Cool S,Entine G,Nagarkar V

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:The aim of this study is to specify the precise role of bone scintigraphy and serum CEA and CA 15-3 assays in the monitoring of breast cancers in order to optimize their use and to determine whether it is possible to guide the prescription of bone scan by the use of CEA and CA 15-3 assays in the monitoring of b...

journal_title：Annals of nuclear medicine

authors： Yildiz M,Oral B,Bozkurt M,Cobaner A

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Dopamine transporter imaging with SPECT is a valuable tool for both clinical routine and research studies. Semi-quantitative analysis plays a key role in interpreting the scans, but is dependent on numerous factors, rotational radius being one of them. This study systematically evaluates the potential influen...

journal_title：Annals of nuclear medicine

authors： Koch W,Bartenstein P,la Fougère C

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Dementia with Lewy bodies (DLB) is generally characterized by a decrease in regional cerebral blood flow (rCBF) in the occipital lobe. However, not all patients with DLB have this feature. We explored characteristics of rCBF pattern changes to improve the identification of DLB, in addition to occipital hypope...

journal_title：Annals of nuclear medicine

authors： Shimizu S,Hanyu H,Hirao K,Sato T,Iwamoto T,Koizumi K

更新日期：2008-12-01 00:00:00

abstract：:We report a functional neuroimaging study of a patient clinically diagnosed with Korsakoff syndrome. Positron emission tomography (PET) with the 15O inhalation method showed decreased regional cerebral blood flow (rCBF) and decreased regional cerebral metabolic ratio for oxygen (rCMRO2) in the bilateral fronto-tempora...

journal_title：Annals of nuclear medicine

authors： Matsuda K,Yamaji S,Ishii K,Sasaki M,Sakamoto S,Kitagaki H,Imamura T,Mori E

更新日期：1997-02-01 00:00:00

abstract：AIM:The purpose of the study was to determine the lung toxicity caused by amiodarone (AD) and bleomycin (BLM) in rats, by means of Tc-99m HMPAO lung scintigraphy. METHODS:Thirty albino rats were randomly divided into five groups. After AD or BLM was dissolved with isotonic saline (SF), a 0.5 ml solution was applied to...

journal_title：Annals of nuclear medicine

authors： Gumuser G,Vural K,Varol T,Parlak Y,Tuglu I,Topal G,Sayit E

更新日期：2013-08-01 00:00:00

abstract：:In this review I summarize observations of PET and SPECT studies about cerebral blood flow and metabolic abnormalities in Alzheimer's disease. In very early AD flow or metabolism reduces first in the posterior cingulate gyrus and precuneus. This reduction may arise from functional deafferentation caused by primary neu...

journal_title：Annals of nuclear medicine

authors： Matsuda H

更新日期：2001-04-01 00:00:00

abstract：:Most of the acute ischemic events, such as acute coronary syndromes and stroke, are attributed to vulnerable plaques. These lesions have common histological and pathophysiological features, including inflammatory cell infiltration, neo-angiogenesis, remodelling, haemorrhage predisposition, thin fibrous cap, large lipi...

journal_title：Annals of nuclear medicine

authors： Giannakou S,Angelidis G,Tsougos I,Valotassiou V,Kappas K,Georgoulias P

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Radium-223 (223Ra) has been approved for treatment in patients with metastatic castration-resistant prostatic cancer (mCRPC) and bone metastasis. This α-emitting radionuclide has a beneficial effect on pain and is also capable to increase overall survival (OS). Several studies evaluated the prognostic value o...

journal_title：Annals of nuclear medicine

authors： Frantellizzi V,Monari F,Mascia M,Costa R,Rubini G,Spanu A,Di Rocco A,Lodi Rizzini E,Cindolo L,Licari M,Lavelli V,Nuvoli S,De Angelis C,Dionisi V,Ferrari C,De Vincentis G

更新日期：2020-10-01 00:00:00

abstract：AIM:The presence of an elevated copper concentration in cancer cells may be potentially used to differentiate healthy from transformed cells. In this study, we aimed to look at the possible role of (64)CuCl2 PET/CT in staging of patients with prostate cancer (PC). METHODS:Seven patients affected by histologically conf...

journal_title：Annals of nuclear medicine

authors： Capasso E,Durzu S,Piras S,Zandieh S,Knoll P,Haug A,Hacker M,Meleddu C,Mirzaei S

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The maximal safe dose (MSD) on the basis of bone marrow irradiation levels allows the delivery of a large amount of I-131 to thyroid cancer tissue. The efficacy of MSD therapy in differentiated metastatic thyroid cancers that persisted after conventional fixed dose therapy is investigated. METHODS:Forty-seve...

journal_title：Annals of nuclear medicine

authors： Lee JJ,Chung JK,Kim SE,Kang WJ,Park DJ,Lee DS,Cho BY,Lee MC

更新日期：2008-11-01 00:00:00

abstract：:We recently experienced a case with uveitis suffering from fever of unknown origin suspected of being caused by sarcoidosis. Chest computed tomography showed right supraclavicular, bilateral mediastinal, and right hilar lymphadenopathy, and intensive abnormal uptake of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) was obs...

journal_title：Annals of nuclear medicine

authors： Tsujikawa T,Okazawa H,Tsuchida T,Demura Y,Imamura Y,Fujibayashi Y

更新日期：2007-08-01 00:00:00

abstract：AIM:Computer-aided diagnosis (CAD) software for bone scintigrams have recently been introduced as a clinical quality assurance tool. The purpose of this study was to compare the diagnostic accuracy of two CAD systems, one based on a European and one on a Japanese training database, in a group of bone scans from Japanes...

journal_title：Annals of nuclear medicine

authors： Horikoshi H,Kikuchi A,Onoguchi M,Sjöstrand K,Edenbrandt L

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic value of fluorine-18 fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) using standard uptake values (SUV) in the differential diagnoses of indeterminate pulmonary nodules. Specifically, we assessed the probability of malignancy for various SUV ranges, and compared the di...

journal_title：Annals of nuclear medicine

authors： Kim SC,Machac J,Krynyckyi BR,Knesaurek K,Krellenstein D,Schultz B,Gribetz A,DePalo L,Teirstein A,Kim CK

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:The quality of images reconstructed by means of the maximum likelihood-expectation maximization (ML-EM) and ordered subset (OS)-EM algorithms, was examined with parameters such as the number of iterations and subsets, then compared with the quality of images reconstructed by the filtered back projection method....

journal_title：Annals of nuclear medicine

authors： Takahashi Y,Murase K,Higashino H,Sogabe I,Sakamoto K

更新日期：2001-12-01 00:00:00

abstract：:Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein highly expressed by prostate cancer cells. PSMA-based radioligand therapy (RLT) emerged as a promising therapeutic option for prostate cancer in the early 2000s, and has been clinically validated with great enthusiasm during these past two decad...

journal_title：Annals of nuclear medicine

authors： Inubushi M,Miura H,Kuji I,Ito K,Minamimoto R

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:One of the major causes of diabetes and obesity is abnormality in glucose metabolism and glucose uptake in the muscle and adipose tissue based on an insufficient action of insulin. Therefore, many of the drug discovery programs are based on the concept of stimulating glucose uptake in these tissues. Improveme...

journal_title：Annals of nuclear medicine

authors： Ishino S,Sugita T,Kondo Y,Okai M,Tsuchimori K,Watanabe M,Mori I,Hosoya M,Horiguchi T,Kamiguchi H

更新日期：2017-06-01 00:00:00

abstract：:Technetium-99m tetrofosmin and thallium-201 lung SPECT imaging were performed in a patient with adenocarcinoma of the lung. Significant activities in the lung lesion were clearly depicted on both technetium-99m tetrofosmin and thallium-201 SPECT imaging. The early uptake, delayed uptake ratios and retention indices of...

journal_title：Annals of nuclear medicine

authors： Matsunari I,Kinuya S,Nishikawa T,Matoba M,Murakita K,Ohguchi M,Ichiyanagi K,Taki J,Tonami N,Hisada K

更新日期：1996-02-01 00:00:00

abstract：:We present a comprehensive review of Neuroendocrine Tumors (NET) and the current and developing imaging and therapeutic modalities for NET with emphasis on Nuclear Medicine modalities. Subsequently, nanotechnology and its emerging role in cancer management, especially NET, are discussed. The article is both educative ...

journal_title：Annals of nuclear medicine

authors： Arora G,Bandopadhyaya G

更新日期：2018-04-01 00:00:00

abstract：:Currently, imaging techniques are the leading methods used to diagnose of metastasis to bone. However, these techniques are expensive, expose patients to toxic and radioactive compounds, and monitor response to treatment poorly; these drawbacks have prompted the search for alternative screening methods. Therefore, bon...

journal_title：Annals of nuclear medicine

authors： Koizumi M,Ogata E

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:Although dual-energy (DE) acquisition with conventional 201Tl myocardial perfusion SPECT has several advantages such as improved attenuation of the inferior wall and increased acquisition counts, the characteristics of IQ-SPECT have not been fully evaluated. We evaluate the difference of characteristics betw...

journal_title：Annals of nuclear medicine

authors： Shibutani T,Onoguchi M,Yoneyama H,Konishi T,Matsuo S,Nakajima K,Kinuya S

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Despite recent technological advances allowing for quantitative single-photon emission computed tomography (SPECT), quantitative SPECT has not been widely used in the clinical practice of osteoporosis. The aim of this study is to evaluate the feasibility of quantitative bone SPECT/CT for measuring lumbar sta...

journal_title：Annals of nuclear medicine

authors： Huang K,Feng Y,Liu D,Liang W,Li L

更新日期：2020-02-01 00:00:00