Risk estimates of dengue in travelers to dengue endemic areas using mathematical models.

Abstract:

BACKGROUND:Dengue has emerged as a frequent problem in international travelers. The risk depends on destination, duration, and season of travel. However, data to quantify the true risk for travelers to acquire dengue are lacking. METHODS:We used mathematical models to estimate the risk of nonimmune persons to acquire dengue when traveling to Singapore. From the force of infection, we calculated the risk of dengue dependent on duration of stay and season of arrival. RESULTS:Our data highlight that the risk for nonimmune travelers to acquire dengue in Singapore is substantial but varies greatly with seasons and epidemic cycles. For instance, for a traveler who stays in Singapore for 1 week during the high dengue season in 2005, the risk of acquiring dengue was 0.17%, but it was only 0.00423% during the low season in a nonepidemic year such as 2002. DISCUSSION:Risk estimates based on mathematical modeling will help the travel medicine provider give better evidence-based advice for travelers to dengue endemic countries.

journal_name

J Travel Med

authors

Massad E,Wilder-Smith A

doi

10.1111/j.1708-8305.2009.00310.x

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

191-3

issue

3

eissn

1195-1982

issn

1708-8305

pii

JTM310

journal_volume

16

pub_type

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