Abstract:
:Infectious mononucleosis (IM), resulting from Epstein-Barr virus (EBV) infection, and IM-like syndromes, mainly due to cytomegalovirus (CMV), Toxoplasma gondii, or human immunodeficiency virus (HIV), have been occasionally reported in travelers returning from the tropics. Our objective was to investigate the prevalence, outcome, and diagnostic predictors of these syndromes in febrile travelers. Between April 2000 and March 2005, all febrile travelers and migrants presenting at our referral centers within 12 months after a tropical stay were prospectively included. We identified all patients serologically diagnosed with IM or IM-like syndrome and compared them with the rest of the cohort. During the 5-year period, 72/1,842 patients (4%) were diagnosed with an IM-like syndrome, including 36 CMV, 16 T gondii, 15 EBV, and 5 HIV primary infections. All patients were western travelers or expatriates. Mean delay before consultation was 2 weeks. Most patients had consulted other practitioners and/or received presumptive treatment. A minority of patients presented with IM clinical features. Lymphocytosis > or =40% of the white blood cells (WBC) and reactive/atypical lymphocyte morphology were observed in 60 and 30% of the patients. The four diseases were indistinguishable. Protracted fever and asthenia were common but complications rarely occurred. IM-like syndromes were independently associated with fever >7 days, lymphadenopathy, elevated liver enzymes, and lymphocytosis > or =40% of WBC. Diagnostic probability increased to >20% if at least three of these predictors were present. Diagnosis of IM and IM-like syndrome is not uncommon in febrile travelers, with a higher proportion of primary CMV, T gondii, and HIV infections than in nonimported series. Consequently, classic IM clinical and laboratory features are often lacking. All four pathogens should be systematically considered because early diagnosis should avoid unnecessary investigations and treatment and allow early intervention in case of primary HIV infection.
journal_name
J Travel Medjournal_title
Journal of travel medicineauthors
Bottieau E,Clerinx J,Van den Enden E,Van Esbroeck M,Colebunders R,Van Gompel A,Van den Ende Jdoi
10.1111/j.1708-8305.2006.00049.xsubject
Has Abstractpub_date
2006-07-01 00:00:00pages
191-7issue
4eissn
1195-1982issn
1708-8305pii
JTM49journal_volume
13pub_type
杂志文章abstract::We report two cases of symptomatic neurocysticercosis in two migrants whose negative serology delayed appropriate treatment for 9 and 6 months, respectively. Seroconversion occurred after treatment, which was associated with paradoxical reaction in one patient. Long-term outcome was good in both patients. ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00658.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:In 1993 more than 1 million Swiss residents traveled to a tropical or subtropical country. Although most pretravel advice is given by general practitioners, a number of travelers also seek advice from pharmacists. Little is known about the quantity and quality of travel advice given or the sources of informa...
journal_title:Journal of travel medicine
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1708-8305.1999.tb00838.x
更新日期:1999-06-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2008.00217.x
更新日期:2008-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-09-26 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.19102
更新日期:2004-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12139
更新日期:2014-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12211
更新日期:2015-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.19202
更新日期:2004-11-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12132
更新日期:2014-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 历史文章,杂志文章,评审
doi:10.1111/jtm.12005
更新日期:2013-03-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2009.00343.x
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Health-care professionals can help travelers by providing accurate pre-travel counseling for mosquito-transmitted diseases such as malaria, yellow fever, and dengue fever. Governments and international organizations will benefit from knowledge survey among health professionals in this field to promote the de...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2010.00483.x
更新日期:2011-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2005.12401
更新日期:2005-07-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.13640
更新日期:2004-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1996.tb00726.x
更新日期:1996-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2008.00202.x
更新日期:2008-07-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2008.00253.x
更新日期:2009-01-01 00:00:00
abstract:Background:The novel oral antibiotic formulation Rifamycin SV-MMX®, with a targeted delivery to the distal small bowel and colon, was superior to placebo in treating travellers' diarrhea (TD) in a previous study. Thus, a study was designed to compare this poorly absorbed antibiotic with the systemic agent ciprofloxacin...
journal_title:Journal of travel medicine
pub_type: 杂志文章,随机对照试验
doi:10.1093/jtm/tay116
更新日期:2018-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 临床试验,杂志文章
doi:10.2310/7060.2005.12305
更新日期:2005-05-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章,多中心研究
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更新日期:2013-11-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
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更新日期:1996-03-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12066
更新日期:2014-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2010.00438.x
更新日期:2010-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00550.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Several live attenuated vaccines against bacterial enteric pathogens have recently been licensed. These include the Salmonella typhi Ty21a typhoid vaccine (Vivotif Berna(R) Vaccine) and Vibrio cholerae CVD103-HgR cholera vaccine (Mutacol Berna(R) Vaccine). They comprise a unique class of biologics in which p...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1998.tb00449.x
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Schistosomiasis is common in many African regions and poses a risk for travelers and the local population. So far, schistosomiasis in travelers or expatriates returning from the Tanzanian bank of Lake Tanganyika has not been reported. METHODS:We report a group of students who sought treatment with signs of ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12069
更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/jtm/taaa035
更新日期:2020-07-14 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2004.13609
更新日期:2004-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1111/jtm.12147
更新日期:2014-11-01 00:00:00