Acceptability of hypothetical dengue vaccines among travelers.

Abstract:

BACKGROUND:Dengue viruses have spread widely in recent decades and cause tens of millions of infections mostly in tropical and subtropical areas. Vaccine candidates are being studied aggressively and may be ready for licensure soon. METHODS:We surveyed patients with past or upcoming travel to dengue-endemic countries to assess rates and determinants of acceptance for four hypothetical dengue vaccines with variable efficacy and adverse event (AE) profiles. Acceptance ratios were calculated for vaccines with varied efficacy and AE risk. RESULTS:Acceptance of the four hypothetical vaccines ranged from 54% for the vaccine with lower efficacy and serious AE risk to 95% for the vaccine with higher efficacy and minor AE risk. Given equal efficacy, vaccines with lower AE risk were better accepted than those with higher AE risk; given equivalent AE risk, vaccines with higher efficacy were better accepted than those with lower efficacy. History of Japanese encephalitis vaccination was associated with lower vaccine acceptance for one of the hypothetical vaccines. US-born travelers were more likely than non-US born travelers to accept a vaccine with 75% efficacy and a risk of minor AEs (p = 0.003). Compared with North American-born travelers, Asian- and African-born travelers were less likely to accept both vaccines with 75% efficacy. CONCLUSIONS:Most travelers would accept a safe and efficacious dengue vaccine if one were available. Travelers valued fewer potential AEs over increased vaccine efficacy.

journal_name

J Travel Med

authors

Benoit CM,MacLeod WB,Hamer DH,Sanchez-Vegas C,Chen LH,Wilson ME,Karchmer AW,Yanni E,Hochberg NS,Ooi WW,Kogelman L,Barnett ED

doi

10.1111/jtm.12056

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

346-51

issue

6

eissn

1195-1982

issn

1708-8305

journal_volume

20

pub_type

杂志文章,多中心研究
  • Evidence-based risk assessment and communication: a new global dengue-risk map for travellers and clinicians.

    abstract:BACKGROUND:International travel can expose travellers to pathogens not commonly found in their countries of residence, like dengue virus. Travellers and the clinicians who advise and treat them have unique needs for understanding the geographic extent of risk for dengue. Specifically, they should assess the need for pr...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1093/jtm/taw062

    authors: Jentes ES,Lash RR,Johansson MA,Sharp TM,Henry R,Brady OJ,Sotir MJ,Hay SI,Margolis HS,Brunette GW

    更新日期:2016-09-13 00:00:00

  • Migrants' admissions to hospital: a retrospective study in Como from 1994 to 1998.

    abstract:BACKGROUND:International migrants represent only 4.5% of the world's population, but they may become a challenge for host countries. The aim of the study was to assess the impact of this population on health parameters in Como county, on the northern border of Italy. METHODS:A retrospective analysis of migrants' admis...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2000.00082

    authors: Santoro D,Visoná R,Pusterla L,Vigevani GM

    更新日期:2000-11-01 00:00:00

  • A profile of travelers--an analysis from a large swiss travel clinic.

    abstract:BACKGROUND:Globally, the Swiss have one of the highest proportions of the population traveling to tropical and subtropical countries. Large travel clinics serve an increasing number of customers with specific pre-travel needs including uncommon destinations and preexisting medical conditions. This study aims to identif...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/jtm.12139

    authors: Bühler S,Rüegg R,Steffen R,Hatz C,Jaeger VK

    更新日期:2014-09-01 00:00:00

  • Dengue-associated hemophagocytic syndrome in a Japanese traveler: a case report.

    abstract::Hemophagocytic syndrome (HPS) can develop as a complication of dengue in rare cases, but its relationship with dengue is not well known. We report a case of dengue-associated HPS with liver involvement and coagulopathy. The patient, a Japanese female traveler who had recently returned from Thailand, had severe complic...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/jtm.12158

    authors: Kobayashi K,Hikone M,Sakamoto N,Iwabuchi S,Kashiura M,Takasaki T,Fujita H,Ohnishi K

    更新日期:2015-01-01 00:00:00

  • Seroconversion of neurocysticercosis occurring after anti-helminthic treatment.

    abstract::We report two cases of symptomatic neurocysticercosis in two migrants whose negative serology delayed appropriate treatment for 9 and 6 months, respectively. Seroconversion occurred after treatment, which was associated with paradoxical reaction in one patient. Long-term outcome was good in both patients. ...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2012.00658.x

    authors: Dournon N,Epelboin L,Brion MC,Paris L,Bricaire F,Caumes E

    更新日期:2012-12-01 00:00:00

  • The Japanese need travel vaccinations.

    abstract::At a travel clinic in Kathmandu we reviewed the vaccination records from March 1997 to March 1998 for all travelers to developing countries like Nepal, for two important vaccines, namely, typhoid and hepatitis A. These travelers visited the clinic for various medical problems. One of the reasons for doing this study w...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2000.00011

    authors: Basnyat B,Pokhrel G,Cohen Y

    更新日期:2000-01-01 00:00:00

  • Fatal and severe box jellyfish stings, including Irukandji stings, in Malaysia, 2000-2010.

    abstract:BACKGROUND:Jellyfish are a common cause of injury throughout the world, with fatalities and severe systemic events not uncommon after tropical stings. The internet is a recent innovation to gain information on real-time health issues of travel destinations, including Southeast Asia. METHODS:We applied the model of int...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2011.00531.x

    authors: Lippmann JM,Fenner PJ,Winkel K,Gershwin LA

    更新日期:2011-07-01 00:00:00

  • Two Norwegian patients with melioidosis presenting with bacteraemia and splenic and prostatic abscesses.

    abstract::Infections caused by Burkholderia pseudomallei are rare in nonendemic areas, such as Scandinavia. We report the first two cases of melioidosis in Norway presenting with bacteraemia and splenic and prostatic abscesses, respectively. ...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2011.00550.x

    authors: Hesstvedt L,Wilhelmsen M,Mengshoel AT,Dyrhol-Riise AM

    更新日期:2011-11-01 00:00:00

  • Urticaria and periorbital edema as prodromal presenting signs of acute hepatitis B infection.

    abstract::A 34-year-old patient presented with giant, transient urticarial skin lesions and periorbital edema after a 3-month stay in DR Congo. Retrospective analysis of stored samples revealed that these signs were prodromal manifestations of acute hepatitis B infection. The hepatitis B infection was spontaneously cleared; the...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2011.00507.x

    authors: van Aalsburg R,de Pagter AP,van Genderen PJ

    更新日期:2011-05-01 00:00:00

  • Patient compliance in the use of Vivotif Berna(R) vaccine, typhoid vaccine, live oral Ty21a.

    abstract:BACKGROUND:Several live attenuated vaccines against bacterial enteric pathogens have recently been licensed. These include the Salmonella typhi Ty21a typhoid vaccine (Vivotif Berna(R) Vaccine) and Vibrio cholerae CVD103-HgR cholera vaccine (Mutacol Berna(R) Vaccine). They comprise a unique class of biologics in which p...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.1998.tb00449.x

    authors: Cryz SJ Jr

    更新日期:1998-03-01 00:00:00

  • Remote sensing and malaria risk for military personnel in Africa.

    abstract:BACKGROUND:Nonimmune travelers in malaria-endemic areas are exposed to transmission and may experience clinical malaria attacks during or after their travel despite using antivectorial devices or chemoprophylaxis. Environment plays an essential role in the epidemiology of this disease. Remote-sensed environmental infor...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2008.00202.x

    authors: Machault V,Orlandi-Pradines E,Michel R,Pagès F,Texier G,Pradines B,Fusaï T,Boutin JP,Rogier C

    更新日期:2008-07-01 00:00:00

  • Environmental hazards in Nepal: altitude illness, environmental exposures, injuries, and bites in travelers and expatriates.

    abstract:BACKGROUND:Adventure travel necessarily places travelers at risk of environmental hazards. We assessed the burden of "environmental" hazards among a cohort of travelers and expatriates presenting to a large travel clinic in Nepal. METHODS:Data on travelers and expatriates seen at the Canadian International Water and E...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2007.00145.x

    authors: Boggild AK,Costiniuk C,Kain KC,Pandey P

    更新日期:2007-11-01 00:00:00

  • Predictors for the uptake of recommended vaccinations in Mecca travelers who visited the Public Health Service Amsterdam for mandatory meningitis vaccination.

    abstract:BACKGROUND:Hajj, the pilgrimage to Mecca, is one of the obligatory religious duties of Islam. The travel clinic of the Public Health Service (PHS) Amsterdam administers vaccinations, including the required meningitis ACYW135 vaccine, and provides travelers with individual recommendations for all their travels. METHODS...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2011.00515.x

    authors: Keles H,Sonder GJ,van den Hoek A

    更新日期:2011-05-01 00:00:00

  • Myiasis in Travelers.

    abstract:BACKGROUND:Cutaneous myiasis is a well-established diagnosis in returning travelers from tropical countries. The most common form of myiasis seen in this population is localized furuncular myiasis caused by Dermatobia hominis and Cordylobia anthropophaga. There are limited data on the disease course and outcome in trav...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/jtm.12203

    authors: Lachish T,Marhoom E,Mumcuoglu KY,Tandlich M,Schwartz E

    更新日期:2015-07-01 00:00:00

  • The changing landscape of travel health services in Canada.

    abstract::Canadians are increasingly travelling to areas that would necessitate a pre-travel consultation. Changes in professional regulations in Canada allow greater autonomy of nurses and pharmacists, resulting in shifts in provision of travel health services. We surveyed 824 Canadian travel clinics, 270 (33%) of whom respond...

    journal_title:Journal of travel medicine

    pub_type: 社论,评审

    doi:10.1093/jtm/tay032

    authors: Bui YG,Kuhn SM,Sow M,McCarthy AE,Geduld J,Milord F

    更新日期:2018-05-01 00:00:00

  • Travel health information at commercial travel websites.

    abstract:BACKGROUND:Internet travel purchases accounted for 10% of the travel industry revenue generated in 2001. To ensure that travelers remain healthy during excursions to developing countries, travel health information needs to be available at commercial travel websites. We evaluated the current availability of travel healt...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2003.2699

    authors: Horvath LL,Murray CK,DuPont HL

    更新日期:2003-09-01 00:00:00

  • An outbreak of acute pulmonary histoplasmosis in members of a trekking trip in Martinique, French West Indies.

    abstract:BACKGROUND:Thirteen clustered cases of American histoplasmosis, a deep mycosis caused by Histoplasma capsulatum and acquired through inhalation of airborne spores was reported. Twenty-five persons traveled in Martinique, French West Indies. Thirteen underwent trekking and passed through a mountain tunnel full of bats (...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2003.31755

    authors: Salomon J,Flament Saillour M,De Truchis P,Bougnoux ME,Dromer F,Dupont B,de Saint-Hardouin G,Perronne C

    更新日期:2003-03-01 00:00:00

  • Trends in knowledge, attitudes, and practices of travel risk groups toward prevention of hepatitis A: results from the Dutch Schiphol Airport survey 2002 to 2009.

    abstract:BACKGROUND:Previous studies investigating the travelers' knowledge, attitudes, and practices (KAP) profile indicated an important educational need among those traveling to risk destinations. Initiatives to improve such education should target all groups of travelers, including business travelers, those visiting friends...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2011.00578.x

    authors: van Genderen PJ,van Thiel PP,Mulder PG,Overbosch D,Dutch Schiphol Airport Study Group.

    更新日期:2012-01-01 00:00:00

  • Knowledge, attitudes and practices in travel-related infectious diseases: the European airport survey.

    abstract:BACKGROUND:The European Travel Health Advisory Board conducted a cross-sectional pilot survey to evaluate current travel health knowledge, attitudes and practices (KAP) and to determine where travelers going to developing countries obtain travel health information, what information they receive, and what preventive tra...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2004.13609

    authors: Van Herck K,Van Damme P,Castelli F,Zuckerman J,Nothdurft H,Dahlgren AL,Gisler S,Steffen R,Gargalianos P,Lopéz-Vélez R,Overbosch D,Caumes E,Walker E

    更新日期:2004-01-01 00:00:00

  • Cabin location and the likelihood of motion sickness in cruise ship passengers.

    abstract:BACKGROUND:The prevalence of motion sickness approaches 100% on rough seas. Some previous studies have reported a strong association between location on a ship and the risk of motion sickness, whereas other studies found no association. This study was undertaken to determine if there is a statistical association betwee...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2000.00042

    authors: Gahlinger PM

    更新日期:2000-05-01 00:00:00

  • Candiru--a little fish with bad habits: need travel health professionals worry? A review.

    abstract:BACKGROUND:Over the last 150 years, a little South American fish with alleged unsavory habits has become the stuff legends are made of. With growing visitor numbers to the Amazon basin, the question of whether the animal poses a threat to the many travelers to the region arises. METHODS:Scientific literature was ident...

    journal_title:Journal of travel medicine

    pub_type: 历史文章,杂志文章,评审

    doi:10.1111/jtm.12005

    authors: Bauer IL

    更新日期:2013-03-01 00:00:00

  • Travel-related morbidity in children: a prospective observational study.

    abstract:OBJECTIVE:Scarce data are available on the occurrence of ailments and diseases in children during travel. We studied the characteristics and frequencies of ailments in children aged 0 to 18 years and their parents during traveling. METHODS:A prospective observational study on ailments reported by children and parents ...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2011.00551.x

    authors: van Rijn SF,Driessen G,Overbosch D,van Genderen PJ

    更新日期:2012-05-01 00:00:00

  • Predictive factors of imported malaria in 272 febrile returning travelers seen as outpatients.

    abstract:BACKGROUND:We conducted a prospective study to evaluate the aetiologies of fever in returning travelers and to identify the clinical and laboratory factors predictive of malaria in travelers returning from tropical areas with fever. METHODS:We included those consulting for fever appearing less than 3 months after retu...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2009.00382.x

    authors: Ansart S,Perez L,Thellier M,Danis M,Bricaire F,Caumes E

    更新日期:2010-03-01 00:00:00

  • International regulations for automobile driving and epilepsy.

    abstract:BACKGROUND:Many patients with epilepsy travel abroad and drive automobiles with the assumption that policies, rules, and regulations on epilepsy and driving are similar to those of their home countries. This paper investigates the driving restrictions and other pertinent information on this issue in foreign countries. ...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2000.00001

    authors: Ooi WW,Gutrecht JA

    更新日期:2000-01-01 00:00:00

  • Screening for fever by remote-sensing infrared thermographic camera.

    abstract:BACKGROUND:Following the severe acute respiratory syndrome (SARS) outbreak, remote-sensing infrared thermography (IRT) has been advocated as a possible means of screening for fever in travelers at airports and border crossings, but its applicability has not been established. We therefore set out to evaluate (1) the fea...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2004.19102

    authors: Chan LS,Cheung GT,Lauder IJ,Kumana CR,Lauder IJ

    更新日期:2004-09-01 00:00:00

  • Problems and risks of unsolicited e-mails in patient-physician encounters in travel medicine settings.

    abstract:BACKGROUND:International travel and use of modern information technology are expressions of modern life style. Seeking on-line travel health advice via E-mail for preventive (teleprevention) or diagnostic reasons may become increasingly popular among patients with financial resources and Internet access. This study was...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2001.24423

    authors: Sing A,Salzman J,Sing D

    更新日期:2001-05-01 00:00:00

  • Health advice provided to hostelers from Australia: influence of a travelers' information evening.

    abstract:BACKGROUND:Little is known about the health advice provided to hostelers and the role and influence of hosteling organizations' travelers' information evenings in giving travel health advice. This study was designed to investigate these in relation to the Australian context. METHODS:In 1997, hostelers attending travel...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.2310/7060.2002.22460

    authors: Leggat PA

    更新日期:2002-01-01 00:00:00

  • Travel-acquired scrub typhus: emphasis on the differential diagnosis, treatment, and prevention strategies.

    abstract::Scrub typhus should be considered in any febrile patient presenting with a macular rash, a polyadenopathy, an eschar, or a history of environmental exposure in endemic areas. The differential diagnosis includes malaria, typhoid fever, leptospirosis, and arboviroses. Doxycycline 100 mg twice daily for 7 days should be ...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1708-8305.2007.00151.x

    authors: Nachega JB,Bottieau E,Zech F,Van Gompel A

    更新日期:2007-09-01 00:00:00

  • Trichinellosis in immigrants in Switzerland.

    abstract::We describe a case of trichinellosis diagnosed at the Division of Infectious Diseases, Hospital of Lugano, in January 2009. This case was associated with a cluster of cases and was traced to the consumption of contaminated meat after a wild boar hunt in Bosnia. ...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章

    doi:10.1111/j.1708-8305.2012.00603.x

    authors: Lozano Becera JC,Gurtner De la Fuente V,Pozio E,Bernasconi E

    更新日期:2012-05-01 00:00:00

  • Acetazolamide for the prevention of acute mountain sickness--a systematic review and meta-analysis.

    abstract:BACKGROUND:Acetazolamide has been reported to be effective in the prevention of acute mountain sickness (AMS). Our aim was to conduct a systematic review of randomized, placebo-controlled trials of acetazolamide in the prevention of AMS. METHODS:Studies were identified by searching the MEDLINE, Embase, Cochrane Clinic...

    journal_title:Journal of travel medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1708-8305.2012.00629.x

    authors: Ritchie ND,Baggott AV,Andrew Todd WT

    更新日期:2012-09-01 00:00:00