Invasive aspergillosis: epidemiology and environmental study in haematology patients (Sfax, Tunisia).

Abstract:

:Invasive aspergillosis (IA) is a major opportunistic infection in haematology patients. Preventive measures are important to control IA because diagnosis is difficult and the outcome of treatment is poor. We prospectively examined the environmental contamination by Aspergillus and other fungal species and evaluated the prevalence of invasive aspergillosis in the protect unit of haematology. A three-year prospective study (December 2004-September 2007) was carried out in the department of haematology of Hedi Chaker Hospital. Suspected invasive aspergillosis cases were reviewed and classified as proven, probable and possible invasive aspergillosis using the EORTC criteria. During the study period, we collected weekly environmental samples (patient's rooms, tables and acclimatisers) and clinical samples from each patient (nasal, expectoration and auricular). Among 105 neutropenic patients, 16 had probable and 13 had possible IA. A total of 1680 clinical samples were collected and A. flavus was most frequently isolated (79.2%). Analysis of 690 environmental samples revealed that Penicillium (44%) was the most frequent followed by Cladosporium (20%), Aspergillus spp. (18%) and Alternaria (13%). The PCR-sequencing of 30 A. flavus isolates detected from clinical and environmental samples confirmed the mycological identification. Our findings underline the importance of environmental surveillance and strict application of preventive measures.

journal_name

Mycoses

journal_title

Mycoses

authors

Hadrich I,Makni F,Sellami H,Cheikhrouhou F,Sellami A,Bouaziz H,Hdiji S,Elloumi M,Ayadi A

doi

10.1111/j.1439-0507.2009.01710.x

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

443-7

issue

5

eissn

0933-7407

issn

1439-0507

pii

MYC1710

journal_volume

53

pub_type

杂志文章

相关文献

MYCOSES文献大全
  • Successful multimodal therapy of invasive pulmonary and central nervous system aspergillosis in a neutropenic surgical patient: case report and review of the literature.

    abstract::Invasive aspergillosis predominantly occurs in patients with impaired host defence and is often resistant to different therapeutically strategies. However, mortality significantly increases if the central nervous system is affected. In this report, we describe a case of successful treatment of invasive aspergillosis w...

    journal_title:Mycoses

    pub_type: 信件

    doi:10.1111/j.1439-0507.2007.01442.x

    authors: Kaffarnik M,Utzolino S,Blaich A,Hopt UT

    更新日期:2008-01-01 00:00:00

  • Molecular-based assessment of diversity and population structure of Sporothrix spp. clinical isolates from Espírito Santo-Brazil.

    abstract:BACKGROUND:Sporotrichosis is a subcutaneous mycosis caused by Sporothrix species that affects humans and animals. Little information on the genetic diversity and population structure of the pathogen is available for Brazil, which is needed to design effective strategies to tackle the advance of sporotrichosis in endemi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13230

    authors: da Cruz Bahiense Rocha I,Terra PPD,Cardoso de Oliveira R,Lubianca Zanotti R,Falqueto A,de Camargo ZP,Rodrigues AM,Gonçalves SS

    更新日期:2020-12-18 00:00:00

  • An outbreak due to Candida auris with prolonged colonisation and candidaemia in a tertiary care European hospital.

    abstract::Multidrug-resistant Candida auris has emerged as a cause of insidious hospital outbreaks and complicated infections. We present the analysis of an ongoing C. auris outbreak including the largest published series of C. auris bloodstream infection. All C. auris-positive patients from April-2016 to January-2017 were incl...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12781

    authors: Ruiz-Gaitán A,Moret AM,Tasias-Pitarch M,Aleixandre-López AI,Martínez-Morel H,Calabuig E,Salavert-Lletí M,Ramírez P,López-Hontangas JL,Hagen F,Meis JF,Mollar-Maseres J,Pemán J

    更新日期:2018-07-01 00:00:00

  • [Comparative study of the therapy of Candida esophagitis in HIV-1-infected patients with fluconazole or amphotericin B and flucytosine].

    abstract::In 20 HIV-patients (17 male homosexuals, 1 male and 1 female i.v. drug abuser and 1 female patient with M. Willebrand-Jürgens) Candida esophagitis was diagnosed by esophagogastroduodenoscopy. Clinically they presented retrosternal pain or an exacerbation of oral candidosis under local antimycotics. The diagnosis of Ca...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:

    authors: Brockmeyer NH,Hantschke D,Olbricht T,Hengge UA,Goos M

    更新日期:1991-01-01 00:00:00

  • Evaluation of improvement of onychomycosis in HIV-infected patients after initiation of combined antiretroviral therapy without antifungal treatment.

    abstract::Onychomycosis in HIV-infected patients has a prevalence of 20-44% and is more frequently seen with CD4(+) T cell counts ≤450 cel μl(-1). There are case reports of improvement in onychomycosis after initiation of combined antiretroviral therapy (cART), but there are no prospective studies that prove the existence and f...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12350

    authors: Ruíz-López P,Moreno-Coutiño G,Fernández-Martínez R,Espinoza-Hernández J,Rodríguez-Zulueta P,Reyes-Terán G

    更新日期:2015-09-01 00:00:00

  • Confocal laser scanning microscopy as a new valuable tool in the diagnosis of onychomycosis - comparison of six diagnostic methods.

    abstract::Onychomycosis is common and can mimic several different nail disorders. Accurate diagnosis is essential to choose the optimum antifungal therapy. The aim of this study was to evaluate the use of confocal laser scanning microscopy (CLSM) and optical coherence tomography (OCT) as new non-invasive diagnostic tools in ony...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2012.02198.x

    authors: Rothmund G,Sattler EC,Kaestle R,Fischer C,Haas CJ,Starz H,Welzel J

    更新日期:2013-01-01 00:00:00

  • Prevalence of oral Candida in the first year of life.

    abstract::Colonisation of the gastrointestinal tract is influenced by primary microbial exposure and bioactive factors in breastmilk. The aim was to explore the prevalence of oral Candida in the first year of life in relation to selected exposures. Oral Candida was studied in 100 healthy infants at 4 and 8 weeks, 3, 6 and 12 mo...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12355

    authors: Stecksén-Blicks C,Granström E,Silfverdal SA,West CE

    更新日期:2015-09-01 00:00:00

  • Impact of invasive aspergillosis occurring during first induction therapy on outcome of acute myeloid leukaemia (SEIFEM-12B study).

    abstract:BACKGROUND:Acute myeloid leukaemia (AML) patients are at high risk of invasive aspergillosis (IA) after first induction chemotherapy (CHT). Although IA risk factors have been identified, few data are available on impact of IA, occurring during induction phase, on overall AML outcome. PATIENTS AND RESULTS:The end point...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13147

    authors: Candoni A,Farina F,Perruccio K,Di Blasi R,Criscuolo M,Cattaneo C,Delia M,Zannier ME,Dragonetti G,Fanci R,Martino B,Del Principe MI,Fianchi L,Vianelli N,Chierichini A,Garzia M,Petruzzellis G,Nadali G,Verga L,Busca A

    更新日期:2020-10-01 00:00:00

  • Risk factors for candidaemia: A prospective multi-centre case-control study.

    abstract:OBJECTIVES:Candidaemia carries a mortality of up to 40% and may be related to increasing complexity of medical care. Here, we determined risk factors for the development of candidaemia. METHODS:We conducted a prospective, multi-centre, case-control study over 12 months. Cases were aged ≥18 years with at least one bloo...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13211

    authors: Keighley CL,Pope A,Marriott DJE,Chapman B,Bak N,Daveson K,Hajkowicz K,Halliday C,Kennedy K,Kidd S,Sorrell TC,Underwood N,van Hal S,Slavin MA,Chen SC

    更新日期:2020-11-13 00:00:00

  • Case of dermatophyte abscess caused by Trichophyton rubrum: a case report and review of the literature.

    abstract::A 54-year-old Japanese man without apparent immunosuppression presented with nodules with purulent drainage on the right lower leg. He had ringworm of the right leg and tinea unguium. A biopsy specimen of the nodule showed intradermal abscesses with fungal elements, and Trichophyton rubrum was cultured from both the p...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12317

    authors: Inaoki M,Nishijima C,Miyake M,Asaka T,Hasegawa Y,Anzawa K,Mochizuki T

    更新日期:2015-05-01 00:00:00

  • The aetiological agents of superficial cutaneous mycoses in Jos, Plateau State of Nigeria.

    abstract::A survey of superficial skin mycoses was carried out among miners and office workers employed in different establishments in Jos, Nigeria. Mycotic infection was demonstrable by microscopy and culture in 45 (10.4%) subjects: 20 males and 25 females. Malassezia furfur was the predominant aetiological agent, followed by ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1995.tb00058.x

    authors: Ayanbimpe GH,Bello CS,Gugnani HC

    更新日期:1995-05-01 00:00:00

  • Epidemiology of onychomycosis in Italy: prevalence data and risk factor identification.

    abstract::The prevalence of onychomycosis differs according to geographic area and over time and is influenced by several factors. The epidemiology of onychomycosis in Italy is still unclear. To evaluate the prevalence of onychomycosis in a representative sample of the Italian population a group of Dermatologists and General Pr...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12396

    authors: Papini M,Piraccini BM,Difonzo E,Brunoro A

    更新日期:2015-11-01 00:00:00

  • Clinical presentation of invasive aspergillosis.

    abstract::Invasive aspergillosis has increasingly been recognised to cause significant morbidity and mortality in immunocompromised patients. Fever unresponsive to broad-spectrum antibiotics is the earliest and most common sign of an invasive fungal infection. As invasive Aspergillus infections are usually acquired by inhalatio...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.1997.tb00559.x

    authors: Schwartz S,Thiel E

    更新日期:1997-01-01 00:00:00

  • Inhibitory effect of terbinafine on reactive oxygen species (ROS) generation by Candida albicans.

    abstract::Candida albicans, the most important opportunistic fungal pathogen, is able to generate remarkable amounts of reactive oxygen species (ROS). Since ROS are highly cytotoxic, this mechanism may contribute to the pathogenicity of this yeast, including its invasiveness and the inflammatory response of the host. Terbinafin...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1046/j.1439-0507.2002.00756.x

    authors: Sander CS,Hipler UC,Wollina U,Elsner P

    更新日期:2002-06-01 00:00:00

  • Distribution of keratinophilic fungi in desert soil of Kuwait.

    abstract::Forty soil samples from different desert localities in Kuwait were surveyed for keratinophilic and geophilic dermatophytic fungi. Sixteen species classified in 9 genera were recovered on wool baits. Chrysosporium species were the most common fungi: Chr. tropicum (60%), Chr. pannicola (32.5%), Chr. queenslandicum (27.5...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1989.tb02247.x

    authors: al-Musallam AA

    更新日期:1989-06-01 00:00:00

  • Paracoccidioidomycosis in Quillabamba, Peru, and its surroundings.

    abstract::Three cases of paracoccidioidomycosis observed in 1990-1991 in Quillabamba, Peru, and its surroundings are described. The climate and the living conditions of the inhabitants favour paracoccidioidomycosis. It can be assumed that a majority of cases could not be identified, because the symptoms are disguised as other t...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1991.tb00866.x

    authors: Garcia R,Ugarte G,Vidotto V

    更新日期:1991-11-01 00:00:00

  • A novel dimorphic pathogen, Emergomyces orientalis (Onygenales), agent of disseminated infection.

    abstract::A novel dimorphic fungus, Emergomyces orientalis sp. nov. a close relative of systemic pathogens in the family Ajellomycetaceae (Blastomyces, Histoplasma). The fungus is reported in a 64-year-old male from Shanxi, China. The patient developed disseminated skin lesions, productive cough with fever and showed nodular op...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12583

    authors: Wang P,Kenyon C,de Hoog S,Guo L,Fan H,Liu H,Li Z,Sheng R,Yang Y,Jiang Y,Zhang L,Xu Y

    更新日期:2017-05-01 00:00:00

  • Does ampicillin-sulbactam cause false positivity of (1,3)-beta-D-glucan assay? A prospective evaluation of 15 patients without invasive fungal infections.

    abstract::The purpose of this study was to investigate the interaction between intravenous ampicillin-sulbactam treatment and (1,3)-beta-D-glucan (BDG) assay. Fifteen patients with a median age of 60 (16-81) without known risk factors for invasive fungal infections who received a daily dose of 3×2g ampicillin-sulbactam monother...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2011.02131.x

    authors: Metan G,Agkus C,Nedret Koc A,Elmali F,Finkelman MA

    更新日期:2012-07-01 00:00:00

  • Identification of Microsporum canis from dermatophytic pseudomycetoma in paraffin-embedded veterinary specimens using a common PCR protocol.

    abstract::The effectiveness of a simple PCR protocol performed on paraffin-embedded tissues, obtained from histopathologically and culturally diagnosed cases of dermatophytic pseudomycetoma DPM was tested. The specimens were investigated using previously described primers (DH1L and DH1R) targeting the 18S rDNA gene and amplifyi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2007.01368.x

    authors: Nardoni S,Franceschi A,Mancianti F

    更新日期:2007-05-01 00:00:00

  • Management of human immunodeficiency virus-associated cryptococcal meningitis: Current status and future directions.

    abstract::Cryptococcal meningitis (CM) is one of the most common opportunistic infections of acquired immunodeficiency syndrome (AIDS), as well as an important cause of hospitalisation and death. In recent years, the mortality of CM has remained high in HIV/AIDS population, with up to 30%, including within developed countries. ...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12977

    authors: Wu X,Shen Y

    更新日期:2019-10-01 00:00:00

  • Small-dose itraconazole pulse therapy in the treatment of onychomycosis.

    abstract::The aim was to evaluate efficacy and tolerance of a short-schedule treatment regimen using a small dose of itraconazole in pulse intermittently. The open study evaluated the pulse therapy consisting of monthly 1-week cycles of oral itraconazole 200 mg daily for 2-3 consecutive months in 42 patients with onychomycosis....

    journal_title:Mycoses

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1439-0507.1997.tb00258.x

    authors: Wu J,Wen H,Liao W

    更新日期:1997-12-01 00:00:00

  • Invasive candidiasis in the ICU: evidence based and on the edge of evidence.

    abstract::Invasive candidiasis is a common nosocomial infection among critically ill patients, constitutes an important cause of sepsis, and is associated with significant morbidity and mortality. The Infectious Diseases Society of America (IDSA) has created evidence-based guidelines for the management of invasive candidiasis. ...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.2008.01571.x

    authors: Hollenbach E

    更新日期:2008-09-01 00:00:00

  • Prevalence of Candida spp. in hospitalized patients and their risk factors.

    abstract::A total of 133 Candida spp. strains originating from a group of 100 patients from Santa Casa de Misericórdia of Belo Horizonte, Brazil, between March 1995 and December 1996, were first identified and classified into six different species: Candida albicans (51%), C. tropicalis (33%), C. parapsilosis (8%), C. glabrata (...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1046/j.1439-0507.2002.00763.x

    authors: Resende JC,de Resende MA,Saliba JL

    更新日期:2002-10-01 00:00:00

  • Comparative stability, sensitivity and specificity studies with different lots of Blastomyces dermatitidis yeast and mycelial lysate antigens.

    abstract::Comparative studies were performed to assess the stability and lot-to-lot variation of Blastomyces dermatitidis yeast and mycelial phase lysate antigens. Four lots were prepared from each growth phase of B. dermatitidis strain T-58 (canine isolate) during a 14-month period. Serum specimens from dogs with blastomycosis...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1994.tb00293.x

    authors: Orr ML,Bono JL,Abuodeh RO,Williams SJ,Legendre AM,Scalarone GM

    更新日期:1994-06-01 00:00:00

  • Pathogenic fungi in human dwellings.

    abstract::Airborne invasive fungal infections in various risk groups of people suffering from immunodeficiencies are an increasing problem for modern medicine. Because of the acute and rapid course of invasive infections, prevention is of principal significance. Such prevention mainly concerns the control of fungal spores in in...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.1992.tb00877.x

    authors: Staib F

    更新日期:1992-11-01 00:00:00

  • Colorimetric MTT assessment of antifungal activity of D0870 against fluconazole-resistant Candida albicans.

    abstract::The in vitro antifungal activity of D0870 against eight isolates of fluconazole-resistant Candida albicans was compared with that of itraconazole, ketoconazole and miconazole. The colorimetric MTT [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazolium bromide] assay was used to assess the antifungal activities. The...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1998.tb00709.x

    authors: Yang HC,Mikami Y,Yazawa K,Taguchi H,Nishimura K,Miyaji M,Branchini ML,Aoki FH,Yamamoto K

    更新日期:1998-12-01 00:00:00

  • Subcutaneous mucormycosis caused by Mucor hiemalis Wehmer f. luteus (Linnemann) Schipper 1973.

    abstract::The authors report a case of subcutaneous mucormycosis in a diabetic patient with verrucous lesions in the fourth finger of the right hand. Initially diagnosed as a fixed cutaneous sporotrichosis case, success was obtained with the use of potassium iodide with healing of the lesion in a period of nearly 5 months. At p...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.1990.33.5.241

    authors: Costa AR,Porto E,Tayah M,Valente NY,Lacaz Cda S,Maranhão WM,Rodrigues MC

    更新日期:1990-05-01 00:00:00

  • Minireview: Malassezia infections in immunocompromised patients.

    abstract::Malassezia spp. form part of the normal human cutaneous flora and are implicated in several mild, but recurrent cutaneous diseases, such as pityriasis versicolor, Malassezia folliculitis, seborrhoeic dermatitis, and, with lesser frequency, a range of other dermatological disorders. Malassezia spp. have also been assoc...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.2009.01814.x

    authors: Tragiannidis A,Bisping G,Koehler G,Groll AH

    更新日期:2010-05-01 00:00:00

  • Susceptibility and trailing growth of Candida albicans to fluconazole: results of a Korean multicentre study.

    abstract::The work reported here is the first nationwide, multicenter surveillance study conducted in Korea to obtain data on fluconazole susceptibility of Candida albicans (C. albicans) isolates. A total of 1137 isolates of C. albicans obtained from 17 university hospitals in South Korea during the 6-month period, July through...

    journal_title:Mycoses

    pub_type: 信件,多中心研究

    doi:10.1111/j.1439-0507.2006.01329.x

    authors: Lee MK,Kim HR,Kang JO,Kim MN,Kim EC,Kim JS,Kim JJ,Park YJ,Song W,Shin JH,Lee KM,Lee NY,Lee M,Lee WG,Lee CK,Lee HJ,Chang CL,Choi TY

    更新日期:2007-03-01 00:00:00

  • Susceptibility to ketoconazole of Candida albicans strains from sequentially followed HIV-1 patients with recurrent oral candidosis.

    abstract::The MIC values of the antifungal drug ketoconazole were evaluated on 66 Candida albicans strains. These strains were isolated from 26 HIV-1 infected patients with oral recurrent candidosis. Each episode of oral candidosis observed in these patients was orally treated with ketoconazole (200 mg/day) until the clinical d...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1992.tb00819.x

    authors: Bruatto M,Marinuzzi G,Raiteri R,Sinicco A

    更新日期:1992-01-01 00:00:00