Invasive candidiasis in the ICU: evidence based and on the edge of evidence.

Abstract:

:Invasive candidiasis is a common nosocomial infection among critically ill patients, constitutes an important cause of sepsis, and is associated with significant morbidity and mortality. The Infectious Diseases Society of America (IDSA) has created evidence-based guidelines for the management of invasive candidiasis. However, several new antifungal agents with excellent activity against Candida spp. and favourable safety profiles have been introduced successfully in the clinical setting since the IDSA guidelines were published in late 2003. Further, the role of antifungals is not entirely clear in the intensive care unit (ICU) setting. Therefore, this article discusses daily problems in the prophylaxis and treatment of invasive candidasis in interdisciplinary ICUs.

journal_name

Mycoses

journal_title

Mycoses

authors

Hollenbach E

doi

10.1111/j.1439-0507.2008.01571.x

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

25-45

eissn

0933-7407

issn

1439-0507

pii

MYC1571

journal_volume

51 Suppl 2

pub_type

杂志文章,评审

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