Abstract:
:The aim was to evaluate efficacy and tolerance of a short-schedule treatment regimen using a small dose of itraconazole in pulse intermittently. The open study evaluated the pulse therapy consisting of monthly 1-week cycles of oral itraconazole 200 mg daily for 2-3 consecutive months in 42 patients with onychomycosis. After active therapy, patients were evaluated for a maximum period of 1 year. Twelve of 42 patients were considered as being clinically cured, 17 were markedly improved, 11 were improved and two were failures. A mycological examination at the final visit was performed on all patients. Thirty-five were negative and seven were positive. This short treatment was well tolerated, with no adverse reactions, and may offer a new option for treatment of onychomycosis.
journal_name
Mycosesjournal_title
Mycosesauthors
Wu J,Wen H,Liao Wdoi
10.1111/j.1439-0507.1997.tb00258.xsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
397-400issue
9-10eissn
0933-7407issn
1439-0507journal_volume
40pub_type
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