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Carbohydrate metabolism and cardiovascular risk factors 4 years after a pregnancy complicated by gestational diabetes.

Abstract：

AIMS:The aim of the present study was to determine the prevalence of abnormal glucose tolerance and the metabolic syndrome in a cohort of previously gestational diabetic (GDM) women 4 years after delivery. METHODS:Sixty-eight prior GDM and a control group of 39 women with normal glucose tolerance during pregnancy were invited to participate in a follow-up study. RESULTS:The prevalence of diabetes, impaired glucose tolerance and impaired fasting glucose (IFG) was 21%, 16%, and 6% among prior GDM women and 0%, 15%, and 0% among controls respectively (P=0.0039). Independently of the metabolic syndrome criteria used this status was found more frequently among women with prior GDM (all P<0.05). The prevalence of the metabolic syndrome showed a dose-response relationship with the level of weight categories (P<0.005) as well as with the level of glucose intolerance (P=0.024). CONCLUSION:According to our results a disturbed carbohydrate metabolism and a clustering of cardiovascular risk factors might be observed in previous GDM women 4 years after delivery.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Madarász E,Tamás G,Tabák AG,Kerényi Z

doi

10.1016/j.diabres.2009.05.001

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

197-202

issue

2

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(09)00199-5

journal_volume

85

pub_type

杂志文章

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