Oxidation of glycerol by 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) in the presence of laccase.

Abstract:

:Glycerol has the potential of being a low-cost and extremely versatile building block. However, current transformation strategies such based on noble-metal-catalysts show several disadvantages including catalyst deactivation or negative environmental impacts. In this study glycerol was oxidized by 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) in the presence of laccase from Trametes hirsuta. Analysis of the reaction production indicated sequential oxidation to glyceraldehyde, glyceric acid and tartronic acid, finally resulting in mesoxalic acid. The number and nature of oxidation products was depended on the concentration of TEMPO used. At lower TEMPO concentrations (<6mM) the major initial reaction product was glyceraldehyde while at higher concentration in addition considerable amounts of glyceric acid were formed. Glycerol oxidation was also shown with laccase immobilised on alumina pellets which increased laccase stability.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Liebminger S,Siebenhofer M,Guebitz G

doi

10.1016/j.biortech.2009.04.051

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

4541-5

issue

20

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(09)00469-6

journal_volume

100

pub_type

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