Abstract:
BACKGROUND:Bipolar radiofrequency ablation (RFA) can avoid complications such as thermal tissue damage, a possible consequence of monopolar RFA. However, basic studies about the dosage/effect relationship of bipolar systems are missing. This is systematic research on ex vivo beef livers to find which capacity parameters produce high energy in the tissue and achieve large lesion volumes. MATERIALS AND METHODS:The active lengths 20, 30 and 40 mm of a bipolar, internally cooled applicator were studied. The tissue was fresh ex vivo beef liver. Five measurements each for each active applicator with a power between 10 and 50 W were conducted. RESULTS:The best power for the 20 mm applicator was 15 W, since the highest achieved volume was 5,599+/-1,760 mm(3) and the highest amount of energy introduced to the tissue was 15+/-3 kJ. The best power for the 30 mm applicator was 20 W (volume 14,538+/-1,220 mm(3), energy 24+/-1 kJ). For the 40 mm applicator, the best power was 20 W, (volume 20,562+/-896 mm(3), energy 24+/-0 kJ). CONCLUSION:The results of this study help clinicians determine which active length is required for the applicator and which presetting should be selected to achieve a defined coagulation volume size.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Zurbuchen U,Frericks B,Roggan A,Lehmann K,Bössenroth D,Buhr HJ,Ritz JPsubject
Has Abstractpub_date
2009-04-01 00:00:00pages
1309-14issue
4eissn
0250-7005issn
1791-7530pii
29/4/1309journal_volume
29pub_type
杂志文章abstract::MicroRNAs (miRNAs) constitute a dominating class of small RNAs that regulate diverse cellular functions. Due the pivotal role of miRNAs in biological processes, a deregulated miRNA expression is likely involved in human cancers. MicroRNAs possess tumor suppressor capability, as well as display oncogenic characteristic...
journal_title:Anticancer research
pub_type: 杂志文章,评审
doi:10.21873/anticanres.11142
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abstract:BACKGROUND:Malignant glioma is one of the most intractable diseases in the human body. Rho-kinase (ROCK) is overexpressed and has been proposed as the main cause for the refractoriness of the disease. Since efficacious treatment is required, this study investigated the effect of inhibition of ROCK isoforms. MATERIALS ...
journal_title:Anticancer research
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abstract:BACKGROUND:Photodynamic therapy (PDT) is considered a promising new strategy for ovarian cancer treatment. As the key component in PDT, photosensitizer metabolism and localization in cancer cells is particularly important. MATERIALS AND METHODS:The localization of the photosensitizers hematoporphyrin monomethyl ether ...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
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abstract::Glioblastoma multiforme (GBM) is the most aggressive intracranial tumor characterized with infaust prognosis. Despite advances in neurosurgical and radiotherapeutic techniques and chemotherapy, the median overall survival ranges between 12-15 months from diagnosis. The main cause of treatment failure is considered the...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.11422
更新日期:2017-03-01 00:00:00
abstract:AIM:We analyzed pentafecta outcomes [complication-free, continence, potency, negative surgical margins (NSM)], biochemical recurrence (BCR)-free] of 230 patients undergoing robotic-assisted radical prostatectomy (RARP) with bilateral neurovascular (NVB) preservation. PATIENTS AND METHODS:Patient outcomes (group I, cas...
journal_title:Anticancer research
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
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journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.14327
更新日期:2020-06-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract::The present study compared the effects of four lipophilic forms of selenium with regard to cancer chemopreventive activity, tissue selenium accumulation, and bioavailability for synthesis of a selenoprotein. These reagents included methylphenyl selenide, diphenyl selenide, triphenyl-selenonium chloride, and p-xylylbis...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
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journal_title:Anticancer research
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更新日期:2011-09-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-09-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.11562
更新日期:2017-05-01 00:00:00
abstract::Oral mucositis is one of the main complications in non-surgical cancer treatments. It represents the major dose-limiting toxicity for some chemotherapeutic agents, for radiotherapy of the head and neck region and for some radiochemotherapy combined treatments. Many reviews and clinical studies have been published in o...
journal_title:Anticancer research
pub_type: 杂志文章,评审
doi:
更新日期:2007-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND/AIM:Secretory phospholipase-A2 (sPLA2) mediates growth and proliferation of human esophageal adenocarcinoma cells (HEAC). Two major molecular pathways of cancer growth regulation include extracellular signal-regulated kinase 1/2 (ERK 1/2) and protein kinase-B (AKT). Phospholipase enzymes have been demonstrat...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:The albumin-bilirubin (ALBI) grade assesses the severity of liver dysfunction in patients with hepatocellular carcinoma. Herein we investigated the prognostic significance of the combination of the ALBI grade with serum carbohydrate antigen 19-9 (CA 19-9) concentration, the most frequently used tumor marker ...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.13260
更新日期:2019-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract::We report here the first orthotopic transplant model for human ovarian cancer. Histologically-intact patient specimens of ovarian cancer were transplanted by microsurgical techniques under the capsule of the nude mouse ovary. The human tumors grew locally and gave rise to a patient-like metastatic pattern including th...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:A vast majority of patients with metastatic colorectal cancer (mCRC) are not candidates for surgical resection. Radiofrequency ablation (RFA) is a safe and effective technique for treatment of isolated liver metastasis. After radiofrequency ablation, residual tumor can have aggressive growth, part of which i...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Macrophage colony stimulating factor (M-CSF) binds to colony-stimulating factor-1 receptor (CSF-1R) and thereby stimulates the proliferation, differentiation and behaviour of monocytes, macrophages and their bone marrow progenitors. Previous studies have suggested that high expression of these markers is cor...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract::Giant cell tumor (GCT) is a relatively common and locally aggressive benign bone tumor. The sternum is a rare location. To date, only four cases have been reported with detailed information. Here, we present a case with sternal GCT and discuss the clinical manifestation and treatment, in addition to reviewing the lite...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Preclinical studies have indicated that BRCA1 functions differentially to modulate the chemosensitivity of cancer cells. PATIENTS AND METHODS:To clarify these findings, BRCA1 expression in primary tumors was evaluated by immunohistochemistry in 50 patients with metastatic breast cancer. RESULTS:BRCA1 expre...
journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Ovarian cancer is the most lethal malignancy among gynaecological cancers. Although many anticancer agents have been developed for the treatment of ovarian cancer, it continues to have an extremely poor prognosis. Heparin-binding epidermal growth factor-like grown factor (HB-EGF) has been reported to be a rational the...
journal_title:Anticancer research
pub_type: 杂志文章
doi:10.21873/anticanres.11779
更新日期:2017-07-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
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