Abstract：
OBJECTIVE:To conduct a pilot study of amantadine in children with impaired consciousness caused by acquired brain injury, to establish design feasibility, and to assess the effect on level of arousal and consciousness. DESIGN:Randomized, double-blind, placebo-controlled crossover trial. Seven subjects (mean age, 12.7 yrs) with an acquired brain injury (mean duration, 6 wks) were randomized to receive either 3 wks of placebo or amantadine, followed by a 1-wk washout period and then 3 wks of the other agent. Main outcome measures were the Coma/Near-Coma Scale and Coma Recovery Scale-Revised, each done three times per week. Subjective evaluations of change in arousal and consciousness by the parent and physician were done weekly. RESULTS:Five subjects completed the study. There was no significant difference in the slopes of recovery during either arm for the Coma/Near-Coma Scale (P = 0.24) or the Coma Recovery Scale-Revised (P = 0.28), although improvements in consciousness were noted by the physician during weeks when amantadine was given (P = 0.02). CONCLUSIONS:This study suggests that amantadine facilitates recovery of consciousness in pediatric acquired brain injury and provides important information necessary to design future more definitive studies.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
McMahon MA,Vargus-Adams JN,Michaud LJ,Bean Jdoi
10.1097/PHM.0b013e3181a5ade3subject
Has Abstractpub_date
2009-07-01 00:00:00pages
525-32issue
7eissn
0894-9115issn
1537-7385journal_volume
88pub_type
杂志文章,随机对照试验abstract：OBJECTIVE:To evaluate the effect of selective blocking of the anterior branch of the obturator nerve by using phenol in controlling adductor spasticity in children with cerebral palsy. DESIGN:To study the anatomic location of the anterior branch of the obturator nerve with respect to bony landmarks in the inguinal are...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0b013e31815b6381
更新日期：2009-01-01 00:00:00
abstract：:Competence, or decision making capacity, refers to a patient's ability to understand a situation and to make a choice in light of that understanding. It requires the physician to disclose adequate information so that the patient is able to understand and choose. The standard for determining competence is that a person...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the optimal vibration frequency (OVF), which corresponds to maximal electromyographic muscle response during whole-body vibration, between young, middle-aged, and older women in four muscles of the lower-limbs. DESIGN:OVF was measured as the frequency corresponding to max...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0000000000000193
更新日期：2015-07-01 00:00:00
abstract：:This article examines the process of setting goals for patient treatment in rehabilitation. It explores ethical considerations and moral conflict inherent to the formulation of patient goals, and it provides a framework to help resolve such conflicts. Goal setting is also considered within the larger context of justic...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-199308000-00011
更新日期：1993-08-01 00:00:00
abstract：OBJECTIVE:Promoting an active lifestyle through an appropriate physical exercise prescription is one of the major targets of cardiac rehabilitation. However, information on the effectiveness of cardiac rehabilitation in promoting lifestyle changes in elderly patients is still scant. DESIGN:In 131 patients over the age...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0b013e3181b332a1
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this pilot study was to determine the effect of a 1.5-day multidisciplinary fibromyalgia treatment program on impact of illness, depression, and life fulfillment. DESIGN:A sample of 100 consecutive enrollees in a 1.5-day multidisciplinary group outpatient fibromyalgia treatment program between...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/01.PHM.0000046625.72055.35
更新日期：2003-03-01 00:00:00
abstract：:The treatment of inpatients in a contiguous hospital area designated the Arthritis Rehabilitation Unit (ARU) as opposed to the treatment of patients on units discretely spaced throughout the hospital was studied by means of independent retrospective audit of randomly chosen charts with the primary diagnosis of rheumat...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:Additional slips of the triceps brachii have been reported in cadaver studies. We report the case of a 48-year-old man with no history of trauma who presented with a tingling sensation and weakness in his right hand. Electromyography revealed ulnar neuropathy around the elbow, with decreased conduction proximal to the...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0000000000000507
更新日期：2016-10-01 00:00:00
abstract：:Cognitive dysfunction among cancer survivors, commonly referred to as "chemobrain," has gained increased attention in the last decade. Cognitive dysfunction is now well recognized among patients with non-central nervous system cancers. It may be a consequence of the cancer, its treatment, or both. Other common problem...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章,评审
doi：10.1097/PHM.0b013e31820be463
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To document the relationship between sleep disturbance and chronic low back pain in patients referred to a physical medicine and rehabilitation clinic. DESIGN:This is a prospective cross-sectional survey of 268 patients 18 yrs or older being evaluated for low back pain of greater than 6 months at a tertiary ...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/01.phm.0000214259.06380.79
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to compare pain induced by magnetic stimulation of the quadriceps femoris (QF) muscle with that induced by transcutaneous neuromuscular electrical stimulation (NMES). DESIGN:Magnetic stimulation and transcutaneous NMES were applied to QF muscles of 17 normal volunteers. The in...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1097/01.phm.0000223239.93539.fe
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to investigate whether muscle strength declines before or concurrent with incident knee pain in subjects with and without radiographic knee osteoarthritis. DESIGN:Osteoarthritis initiative participants with incident knee pain (occurrence of infrequent/frequent knee pain during the pa...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0000000000001271
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:To investigate the relation between protein expression changes in the cerebellum and improvement of motor coordination in rats with cerebral infarction. DESIGN:The rat group with treadmill training (n = 10) were compared with the rat group without treadmill training (n = 10) after 2.5 hrs of transient middle...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0b013e3181b3323b
更新日期：2010-02-01 00:00:00
abstract：:A case is presented of a 53-yr-old ambulatory ventilator-dependent individual who demonstrated that functional ambulation could be possible with a modified rolling walker. The patient used intermittent positive pressure ventilation delivered by noninvasive methods 24 h a day. For potentially ambulatory ventilator user...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-199210000-00011
更新日期：1992-10-01 00:00:00
abstract：OBJECTIVE:To determine the clinical usefulness of the compound nerve action potential of the common peroneal nerve recorded immediately distal to or at the fibular neck, at the same time stimulating the common peroneal nerve laterally at the posterior knee. DESIGN:For recording the compound nerve action potential of t...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-200102000-00006
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:To compare the sensitivity of median sensory nerve conduction tests performed by stimulating digital branches in patients with carpal tunnel syndrome. DESIGN:A prospective study in 506 hands of patients with carpal tunnel syndrome diagnosed electrophysiologically. RESULTS:The sensitivity of median sensory n...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/01.PHM.0000104662.71129.B9
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine whether the relationship between impaired pulmonary function and level of spinal cord injury would relate to lower maximal ventilation during exercise (Vemax) and hence reduced aerobic capacity. DESIGN:Pulmonary function and maximal aerobic capacity (V˙O2max) were asses...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0000000000000046
更新日期：2014-05-01 00:00:00
abstract：:A hemiplegic patient with severe upper extremity spasticity 2 years after a cerebrovascular accident received a diagnostic median nerve block below the elbow with bupivacaine. He had been placed on Coumadin as prophylaxis for cerebrovascular arteriosclerotic disease, and prothrombin time was kept at twice the control ...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-198804000-00009
更新日期：1988-04-01 00:00:00
abstract：:The purpose of this study was to examine electrophysiologic abnormalities, including motor-evoked potentials, in a patient with post-traumatic syringomyelia before and after syringopleural shunting. A patient with C5 quadriplegia presented with pain, ascending sensory loss, and new weakness in the left upper extremity...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-199012000-00006
更新日期：1990-12-01 00:00:00
abstract：OBJECTIVE:To develop and validate the content of a conceptual framework concerning outcomes for caregivers whose recipients are assistive technology users. DESIGN:The study was designed in four stages. First, a list of potential key variables relevant to the caregivers of assistive technology users was generated from ...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章,评审
doi：10.1097/PHM.0b013e3181ae0e70
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to test the effect of various unstable support surfaces on the relevance of muscular proprioceptive signals originating from the ankle joint. DESIGN:Ten healthy subjects were instructed to stand as still as possible on a force plate during 40 secs on three different surfaces: (1...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0000000000000137
更新日期：2015-01-01 00:00:00
abstract：:This literature review offers physical rehabilitation professionals an update on the current breadth and strength of research evidence regarding comprehensive therapeutic benefits of Taiji practice. A critical analysis distinguishes between what is known from controlled clinical research and what is suggested in preli...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章,评审
doi：10.1097/01.phm.0000137317.98890.74
更新日期：2004-09-01 00:00:00
abstract：:Analyzing multiple nerve conduction study parameters individually is statistically problematic. The goal of this study was to develop a useful factor analysis scheme for assessment of nerve conduction study abnormalities in diabetic neuropathy. Hypotheses were: (1) factor analysis produces a few physiologically meanin...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:The long-term psychosocial and physical functioning impact of an outpatient interdisciplinary pain management program was evaluated by comparison of pain management completors and a no-treatment group. Although pain intensity did not change and there were no significant differences between groups in several aspects of...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-199605000-00014
更新日期：1996-05-01 00:00:00
abstract：:Interest in global health is rising in graduate medical education. Trainees are increasingly seeking high quality, ethically sound, and educationally robust opportunities for global medical rotations. When based on best educational practices, these opportunities can provide a unique learning experience for residents i...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0000000000001652
更新日期：2020-11-26 00:00:00
abstract：OBJECTIVES:To establish the correlations of measures of self-reported disability, self-efficacy, physical performance, level of pain, and estimates of aerobic capacity (PvO2 ) in subjects with low back pain. DESIGN:Fifty-one low back pain subjects, ranging in age from 26 to 65 yr, entered the study. Participants compl...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-200212000-00005
更新日期：2002-12-01 00:00:00
abstract：:Twenty-four women employed as computer operators were evaluated for complaints of occipital headaches, as well as neck and shoulder pain. Although the symptoms were highly variable with respect to duration, intensity and distribution, they were mutually consistent in that they started or intensified with the resumptio...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-198908000-00006
更新日期：1989-08-01 00:00:00
abstract：OBJECTIVE:To assess the effect of a proprioceptive dynamic posture training program on balance in osteoporotic women with kyphotic posture. DESIGN:Subjects were randomly assigned to either a proprioceptive dynamic posture training program or exercise only group. Anthropometric measurements, muscle strength, level of p...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00002060-200204000-00001
更新日期：2002-04-01 00:00:00
abstract：:Intrathecal baclofen withdrawal syndrome is a known complication of intrathecal baclofen pumps. Its origin is postulated as an independent form of a serotonergic syndrome occurring from loss of gamma-aminobutyric acid B receptor-mediated inhibition of serotonin. Prodromal symptoms include pruritus, a return of deep te...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/PHM.0b013e31815b5c58
更新日期：2007-12-01 00:00:00
abstract：:Moyamoya disease is a rare disorder of cerebrovascular circulation. A review of the literature failed to reveal the association of heterotopic ossification in patients with this disease; such a case is now presented. The patient described had atraumatic intracranial hemorrhage, was in a coma for a period of time, unde...
journal_title：American journal of physical medicine & rehabilitation
pub_type： 杂志文章
doi：10.1097/00002060-199809000-00021
更新日期：1998-09-01 00:00:00
