Abstract:
:Intrathecal baclofen withdrawal syndrome is a known complication of intrathecal baclofen pumps. Its origin is postulated as an independent form of a serotonergic syndrome occurring from loss of gamma-aminobutyric acid B receptor-mediated inhibition of serotonin. Prodromal symptoms include pruritus, a return of deep tendon reflexes, and increased spastic hypertonia. Previous reports have documented use of cyproheptadine in treatment of this syndrome in adults with positive results. We present the case of a 14-yr-old child with cerebral palsy who developed pruritus and worsening spastic hypertonia 18 mos after pump implantation. She had been previously treated with 520 microg/day of intrathecal baclofen. Progression of her symptoms was successfully arrested by the administration of both oral and intrathecal baclofen and 6 mg of oral cyproheptadine every 6 hrs for 1 day. We postulate that cyproheptadine should be considered a valuable adjuvant therapy for treatment of suspected intrathecal baclofen withdrawal syndrome.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
Saveika JA,Shelton JEdoi
10.1097/PHM.0b013e31815b5c58subject
Has Abstractpub_date
2007-12-01 00:00:00pages
994-7issue
12eissn
0894-9115issn
1537-7385pii
00002060-200712000-00006journal_volume
86pub_type
杂志文章abstract::There are basic principles and techniques of measurement that are relevant across biomedical disciplines. The purpose of this article is to explain some of the most important of these for medical rehabilitation, to illustrate how to use them to choose assessment instruments and to describe the nature of measurement in...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199102000-00008
更新日期:1991-02-01 00:00:00
abstract:OBJECTIVE:Corticosteroid injection into the carpal tunnel is frequently used for the treatment of carpal tunnel syndrome (CTS). Steroids are usually mixed with local anesthetics, which have positive effects that can aid the treatment of CTS by inhibiting the spontaneous discharge ability of excitable cells. The aim of ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/PHM.0b013e31820639ec
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to examine proprioceptive performance in adults with hemiplegic cerebral palsy and the possibility that a home-based sensorimotor training program could improve proprioceptive performance. DESIGN:This study is a preintervention/postintervention assessment of 12 adults participating ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/PHM.0000000000000100
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:To investigate testosterone and free testosterone levels in male patients after spinal cord injury (SCI) in comparison with healthy subjects, the effects of free testosterone on Functional Independence Measure (FIM) instrument, and their relationship between time since injury, spinal cord injury levels, and ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e318151fa70
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To compare healthcare professionals' assessment of the quality of life of spinal muscular atrophy type 1 children with that of the care providers for the children. DESIGN:The care providers of all 53 surviving spinal muscular atrophy type 1 children managed in one neuromuscular disease clinic were sent Liker...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-200302000-00009
更新日期:2003-02-01 00:00:00
abstract::The purpose of this study was to examine the effect of a low-intensity, alternate-day, 12 wk quadriceps muscle-strengthening exercise program on muscle strength and muscle and motor unit integrity in 12 postpolio patients. Patients performed six to ten repetitions of a 5-s duration knee extension exercise with ankle w...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199601000-00014
更新日期:1996-01-01 00:00:00
abstract::A 17-item questionnaire was designed to assess the relative importance of various factors to physical medicine and rehabilitation (PM&R) training directors when ranking PM&R resident applicants during the National Resident Match. The questionnaire was sent to all PM&R residency training directors. The recipients were ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199406000-00002
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to test whether fractionated irradiation in photobiomodulation therapy enhances short-term recovery in patients with moderate severity ankle sprain. DESIGN:Nineteen patients were randomly assigned to one of two groups: one group receiving photobiomodulation therapy combined with the...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/PHM.0000000000001178
更新日期:2019-08-01 00:00:00
abstract::Rats pretrained to walk a narrow balance beam received unilateral sensorimotor cortex lesions, resulting in a contralateral transient paresis that lasted 14 days. In a dose-dependent manner, a single injection of the antidepressant trazodone given 24 hours after injury transiently slowed motor recovery compared with i...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199310000-00007
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVE:To investigate the hypothesis that the multiple-site injection technique is associated with better outcomes than the single-point injection method in children with cerebral palsy and spastic equinus gait. DESIGN:A total of 17 children (nine boys, eight girls ages 1.8-9.4 yrs; eight hemiplegics, eight diplegi...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/PHM.0b013e31816ddaa9
更新日期:2008-05-01 00:00:00
abstract::Population aging, caused by reductions in fertility and increasing longevity, varies by country and is anticipated to continue and to reach global proportions during the 21st century. Although the effects of population aging have been well documented for decades, the impact of aging on people with spinal cord injury (...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
doi:10.1097/PHM.0b013e31821f70bc
更新日期:2012-01-01 00:00:00
abstract::Competence, or decision making capacity, refers to a patient's ability to understand a situation and to make a choice in light of that understanding. It requires the physician to disclose adequate information so that the patient is able to understand and choose. The standard for determining competence is that a person...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:Dopaminergic agents may stimulate behavior and verbal expression after frontal lobe dysfunction. Although amantadine is used in neurorehabilitation of motivational disorders and head injury, it is not commonly prescribed to improve aphasia. This pilot study examined verbal fluency on and off amantadine for no...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e31811473b3
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVES:To explore an individualized sonographic muscle thickness ratio and its cut-off values in the diagnosis of sarcopenia. DESIGN:A total of 326 community-dwelling adults were included in this cross-sectional study. Total skeletal muscle mass was evaluated by bioelectrical impedance analysis, and 9-site muscle ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001439
更新日期:2020-04-03 00:00:00
abstract::The objective of this study was to determine the effect of two types of restraining belts (lap belt and a four-point belt) on an instrumented dummy during three situations: wheelchair hitting straight into curb (SIC); wheelchair falling straight off a curb (SOC); wheelchair falling diagonally off a curb (DOC). A fully...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199709000-00004
更新日期:1997-09-01 00:00:00
abstract::The purpose of this article is to provide researchers and clinicians with a basic understanding of randomized clinical trials and to discuss their potential application to and limitations in the field of physical medicine and rehabilitation. A brief history of the development of randomized clinical trials, definitions...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
doi:10.1097/00002060-199909000-00016
更新日期:1999-09-01 00:00:00
abstract::Clostridium difficle has been associated with diarrhea in hospitalized patients receiving antibiotic therapy and may be nosocomially acquired. Rehabilitation hospital inpatients may require frequent antibiotic intervention and are thus at risk, although few reports of epidemics at such centers have been published. Thi...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199204000-00008
更新日期:1992-04-01 00:00:00
abstract::Although generally presenting as a chronic, progressive peripheral neuropathy, we present a case of acute alcoholic neuropathy initially mistaken for acute Guillain-Barré syndrome. Electrodiagnostic evaluation of alcoholic neuropathy reveals an axonal neuropathy and may be complicated by demyelination if comorbid nutr...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001244
更新日期:2020-03-01 00:00:00
abstract::A 13-yr-old adolescent boy presented with wrist pain after falling off a scooter onto his outstretched hand. Radiographs revealed a nondisplaced hairline fracture of the scaphoid bone and an irregular radiolucent line in the proximal metaphysis of the second metacarpal bone, consistent with an anomalous growth plate, ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000715
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:The primary aim was to ascertain whether unilateral shoulder pain is implicated in strength reduction both on the ipsilateral and contralateral side. Secondarily, we aimed to determine whether strength was affected by sonographic tendon abnormalities. DESIGN:A total of 122 subjects were evaluated. Sixty-six ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001105
更新日期:2019-05-01 00:00:00
abstract::The combined effects of robotic therapy and botulinum toxin type A (BTX-A) on upper-limb movement and function were studied in an 8(1/2)-yr-old child with hemiplegic cerebral palsy. Robotic therapy comprising repetitive, goal-directed reaching tasks was administered two times per week for 8 wks. Clinical measures incl...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e31817fb346
更新日期:2008-12-01 00:00:00
abstract::Studies were undertaken first to describe the invariant characteristics of gait initiation and second to better understand the function of each limb in the process of gait initiation. Analysis of variance indicated significant main effects for speed for time to onset of EMG activity and force plate recordings, time to...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199108000-00009
更新日期:1991-08-01 00:00:00
abstract:OBJECTIVE:To determine whether individuals who have a spinal cord injury have neuromuscular and physiologic responses to a personalized exercise program during dynamic weight bearing (DWB). DESIGN:Four subjects with spinal cord injuries (T6, T5-6, C2-5, and C5) completed a 12-wk exercise program that included DWB. Sur...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e31805b764b
更新日期:2007-06-01 00:00:00
abstract::A severe injury on the job often results in a medical recovery period requiring either a temporary or long-term absence from work. Rehabilitation interventions emphasizing return to work may facilitate recovery and prevent workers from becoming unemployed. A review of the current literature suggests a direct relations...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199204000-00006
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to systematically review the efficacy and safety of exercise in patients with amyotrophic lateral sclerosis (ALS). DESIGN:Randomized controlled trials of exercises for ALS were searched in PubMed, EMBASE, Web of Science, Cochrane Library, China Biology Medicine database, China Natio...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,meta分析
doi:10.1097/PHM.0000000000001419
更新日期:2020-09-01 00:00:00
abstract::Because of their expertise, physiatrists provide disability insurance assistance for cancer survivors. In this brief report, we perform a descriptive retrospective analysis of all new (354) outpatient physiatry consultations from January 1, 2009, to December 31, 2013, at a National Cancer Institute Comprehensive Cance...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000641
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the effect of a 12-wk exercise therapy program and arthroscopic partial meniscectomy on knee strength and functional performance in middle-aged patients with degenerative meniscus tears. DESIGN:A total of 82 patients (mean age, 49 yrs; 35% women) with a symptomatic, unila...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/PHM.0000000000000209
更新日期:2015-06-01 00:00:00
abstract::We have analyzed the history of institutional fractures in 153 men, age 48 to 96, 86% white, who had resided in this VA nursing home for an average of 6.3 years as of August 1984. At that time, we reviewed their medical charts to record the numbers and sites of fractures which had been diagnosed during the preceding 1...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-198902000-00002
更新日期:1989-02-01 00:00:00
abstract::Visual impairments are common after traumatic brain injury (TBI) and negatively affect quality of life. We describe a 39-year-old woman with a severe TBI who was evaluated by the inpatient optometry and vision rehabilitation service with findings of complete right homonymous hemianopia and right cranial nerve III pals...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000592
更新日期:2017-04-01 00:00:00
abstract::The aim of the study was to assess physiatrists' knowledge of the cost of medications commonly prescribed at discharge from inpatient rehabilitation units across the spectrum of practice experience from residents to attending physicians. Investigators contacted 92 pharmacies across four major regions of the United Sta...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001219
更新日期:2020-02-01 00:00:00