Loop electrosurgical excision of the cervix and subsequent risk for spontaneous preterm delivery: a population-based study of singleton deliveries during a 9-year period.

Abstract:

OBJECTIVE:Our aim was to assess the association between loop electrosurgical excision procedure (LEEP) and the subsequent risk for spontaneous preterm delivery, with the use of population-based data from various nationwide registries. STUDY DESIGN:The study population consisted of all singleton deliveries in Denmark during a 9-year period, 1997-2005. Information on the deliveries that included different cervical procedures was obtained from various national registries. In all, 552,678 deliveries were eligible for analyses. RESULTS:Of the deliveries in which the mother had no previous LEEP, 18,519 deliveries (3.5%) were preterm; when this data were applied to 530 preterm deliveries (6.9%) that were subsequent to LEEP, the yield was a significantly increased risk of preterm delivery, with an odds ratio of 2.07 (95% CI, 1.88-2.27; LEEP vs no LEEP). CONCLUSION:Our study showed an overall 2-fold increase in the risk of spontaneous preterm delivery in singleton deliveries subsequent to LEEP treatment, even after adjustment for various potential risk factors.

journal_name

Am J Obstet Gynecol

authors

Noehr B,Jensen A,Frederiksen K,Tabor A,Kjaer SK

doi

10.1016/j.ajog.2009.02.004

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

33.e1-6

issue

1

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(09)00189-6

journal_volume

201

pub_type

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