Clinical findings among young women with genital human papillomavirus infection.

Abstract:

OBJECTIVE:The purpose of this study was to identify clinical signs and symptoms associated with detection of human papillomavirus (HPV) DNA in the female genital tract. STUDY DESIGN:A total of 516 university students (18 to 24 years old) enrolled in a cohort study that included the collection of genital specimens for HPV DNA testing every 4 months for up to 4 years. Reported symptoms and objective clinical findings of women with and without HPV DNA were compared by multivariate analysis. RESULTS:Acute and persisting HPV infections were not associated with discharge, itching, burning, soreness, or fissures. Clinical evidence of genital warts was statistically associated only with HPV types 6 and 11. Detection of any HPV DNA was associated with bacterial vaginosis (BV). Furthermore, a time lag analysis suggests that HPV infection usually precedes detection of BV. CONCLUSION:Most women who acquire genital HPV infection are asymptomatic; some, however, are at increased risk for BV.

journal_name

Am J Obstet Gynecol

authors

Mao C,Hughes JP,Kiviat N,Kuypers J,Lee SK,Adam DE,Koutsky LA

doi

10.1067/mob.2003.164

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

677-84

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002937802714944

journal_volume

188

pub_type

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