Effects of gender and age on thixotropic properties of whole blood from healthy adult subjects.

Abstract:

:The thixotropic parameters of whole blood from 314 healthy subjects (154 women, 160 men) were measured with our modified method by Low shear 30 Rheometer and calculated according Huang's equation. This communication offered the reference range of thixotropic parameters from man and woman group. The results demonstrated that no significant differences existed in the plasma viscosity and fibrinogen between man and woman group. Man group had statistically higher values in HCT, yield stress (tau 0), Newtonian contribution of viscosity (mu), non-Newtonian contribution of viscosity (eta s--mu), apparent viscosity at 2.37 sec-1 (eta s), the equilibrium value of the structural parameter (A) and apparent kinetic rate constant of rouleaux breakdown (ARC) than those in woman group. The man and woman groups could be separately divided into five subgroups in terms of age. It was found that the levels of fibrinogen and plasma viscosity had a tendency of increasing with aging. In the old subgroup (greater than 60 years) of men and women HCT, tau v, mu, eta s, (eta s--mu) and A had significant lower values than those in young and middle-age subgroups. However, it was very interested that there were differences of ARC versus age between man group and woman group, i.e. ARC in the man subgroup II, IV had lower and the woman subgroup II, III, IV had higher values than their respective older subgroup did.

journal_name

Biorheology

journal_title

Biorheology

authors

Chen HQ,Zhong GH,Li L,Wang XY,Zhou T,Chen ZY

doi

10.3233/bir-1991-283-409

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

177-83

issue

3-4

eissn

0006-355X

issn

1878-5034

journal_volume

28

pub_type

杂志文章
  • Model studies of leukocyte-endothelium-blood interactions. I. The fluid flow drag force on the adherent leukocyte.

    abstract::Using a large scale model and the concept of dimensional similarity, we have developed a dimensionless correlation which permits the estimation of the drag force of blood flow in an in vivo vessel on a leukocyte adherent to the vessel wall. This relationship is [formula: see text] where Re is a Reynolds number, Cd is ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/0006-355X(96)00011-X

    authors: Chapman G,Cokelet G

    更新日期:1996-03-01 00:00:00

  • The effects of margination and red cell augmented platelet diffusivity on platelet adhesion in complex flow.

    abstract::The effects of platelet margination and enhanced platelet diffusivity, as induced by red blood cells, on the adhesion of platelets, were investigated for a range of haematocrits, under 2D axi-symmetric flow, simulating previous in vitro experiments [Microvasc. Res. 17 (1979), 238-262]. The effect of margination was in...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Jordan A,David T,Homer-Vanniasinkam S,Graham A,Walker P

    更新日期:2004-01-01 00:00:00

  • Orbitometer flow and thrombus formation.

    abstract::Orbitometry (Hartert) is a rheological ex-vivo method to follow up physical assembly of a coagulum in layers during natural intensity of flow by orbital movement. Fibrin elasticity in the Orbitometers mode of Resonance Thrombography is differentiated from platelet activity as well as e.g. from the effects of dissemina...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1990-27613

    authors: Hartert H

    更新日期:1990-01-01 00:00:00

  • COX-1, COX-2 and articular joint disease: a role for chondroprotective agents.

    abstract::It is widely accepted that whilst exhibiting clinically useful anti-inflammatory and analgesic activity, the application of non-steroidal anti-inflammatory drugs (NSAIDs) does not affect the underlying pathogenesis of articular diseases such as rheumatoid arthritis. The demonstration of a role for COX-2 in the resolut...

    journal_title:Biorheology

    pub_type: 杂志文章,评审

    doi:

    authors: Colville-Nash PR,Willoughby DA

    更新日期:2002-01-01 00:00:00

  • Limb bud mesenchyme cultured under tensile strain remodel collagen type I tubes to produce fibrillar collagen type II.

    abstract::In this work, we studied the effects of tensile strain on limb bud mesenchymal cells (MSC) cultured on a collagen type I tubular scaffold. A novel bioreactor was designed to culture the cells while subjecting the tubular scaffold to tensile stress and strain. Control samples included unseeded and MSC-seeded tubes cult...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-2009-0553

    authors: Amos JR,Li S,Yost M,Ploehn H,Potts JD

    更新日期:2009-01-01 00:00:00

  • Fibrin elasticity and coagulation.

    abstract::Sudden increase of viscosity in former times indicated the start of coagulation. Yet its measurement destroyed the structure of coagulum. By the precursor method of thrombelastography the author 1944 found elasticity to be the essential physiological property of coagulum. In the production of elastic fibrin structure ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1988-251-221

    authors: Hartert H

    更新日期:1988-01-01 00:00:00

  • Lubricated squeezing flow: a useful method for measuring the viscoelastic properties of soft tissues.

    abstract::Conducting experiments on very soft biological tissues can be difficult. Traditionally, unconfined compression and shear have been used. Here, an improved method of compression testing, lubricated squeezing flow is described. This gives a uniform compression along the squeezing axis and almost uniform equi-biaxial elo...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Nasseri S,Bilston L,Tanner R

    更新日期:2003-01-01 00:00:00

  • Alterations in the biorheological features of some soft tissues after limb lengthening.

    abstract::The aim of this study was to investigate the effects of a surgical limb lengthening procedure on the biorheological features of some lengthened soft tissues. In this procedure external fixators were applied to goats' right radius to stretch the tissues. The right forelegs of goats were lengthened by 2, 4 cm, respectiv...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/S0006-355X(99)80016-X

    authors: Huang K,Zeng Y,Xia H,Liu C

    更新日期:1998-07-01 00:00:00

  • Rheological properties and wall structures of large veins.

    abstract::The static and dynamic viscoelastic properties were studied of longitudinal and circumferential strips excised from various large veins of dogs. The mechanical behavior in longitudinal direction could be regarded as elastic, while that in circumferential direction was highly viscoelastic. No distinct regionality was o...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1983-20510

    authors: Hasegawa M

    更新日期:1983-01-01 00:00:00

  • Hydrostatic pressure modulates mRNA expressions for matrix proteins in human meniscal cells.

    abstract::There have been few reports describing the effects of mechanical loading on the metabolism of meniscal cells. The aim of this study was to investigate the effects of hydrostatic pressure on meniscal cell metabolism. Human meniscal cells were cultured in alginate beads for 3 days. They were then subjected to 4 MPa hydr...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Suzuki T,Toyoda T,Suzuki H,Hisamori N,Matsumoto H,Toyama Y

    更新日期:2006-01-01 00:00:00

  • Phenotypic analysis of cell surface markers and gene expression of human mesenchymal stem cells and chondrocytes during monolayer expansion.

    abstract::Both chondrocytes and mensenchymal stem cells (MSCs) are the most used cell sources for cartilage tissue engineering. However, monolayer expansion to obtain sufficient cells leads to a rapid chondrocyte dedifferentiation and a subsequent ancillary reduced ability of MSCs to differentiate into chondrocytes, thus limiti...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Cournil-Henrionnet C,Huselstein C,Wang Y,Galois L,Mainard D,Decot V,Netter P,Stoltz JF,Muller S,Gillet P,Watrin-Pinzano A

    更新日期:2008-01-01 00:00:00

  • Experimental assessment of wall shear flow in models.

    abstract::The blood flow immediately adjacent to the wall of a blood vessel or an artificial surface is of great interest. This flow defines the shear stress at the wall and is known to have a great physiological importance. The use of models is a viable method to investigate this flow. However, even in models the shear stress ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Affeld K,Kertzscher U,Goubergrits L

    更新日期:2002-01-01 00:00:00

  • Fluid shear stress enhanced DNA synthesis in cultured endothelial cells during repair of mechanical denudation.

    abstract::We have previously observed a stimulatory effect of fluid shear stress on the regeneration of cultured endothelial cell layers after mechanical denudation. In this study we examined how fluid shear stress affects endothelial cell DNA synthesis during regeneration. Following mechanical denudation of narrow linear areas...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1990-27505

    authors: Ando J,Komatsuda T,Ishikawa C,Kamiya A

    更新日期:1990-01-01 00:00:00

  • Intravital-microscopic observations on the intravascular behavior of blood cell components during dietary-induced hyperlipidemia in the male rabbit.

    abstract::In normal male rabbits loaded dietary cholesterol, intravital-microscopy revealed a marked acceleration of intravascular adhesiveness of white blood cells and aggregability of red blood cells and a swarming of lipid-laden macrophages in connective tissue space concurrently with a systemic hyperlipidemia and anemia. Po...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1988-251-242

    authors: Asano M,Ohkubo C,Hirokawa A,Sasaki A,Tochihara Y,Chiba Y

    更新日期:1988-01-01 00:00:00

  • Epinephrine and shear stress synergistically induce platelet aggregation via a mechanism that partially bypasses VWF-GP IB interactions.

    abstract::Elevated shear stress levels in pathologically stenosed vessels induce platelet activation and aggregation, and may play a role in the pathogenesis of arterial disease. Increased plasma catecholamine concentrations have also been implicated in the onset of acute coronary ischemic syndromes. This study was designed to ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/0006-355X(96)00018-2

    authors: Wagner CT,Kroll MH,Chow TW,Hellums JD,Schafer AI

    更新日期:1996-05-01 00:00:00

  • Influence of plaque stiffness on deformation and blood flow patterns in models of stenosis.

    abstract:BACKGROUND:Blood flow in stenotic vessels strongly influences the progression of vascular diseases. Plaques in stenotic blood vessels vary in stiffness, which influences plaque behavior and deformation by pressure and flow. Concurrent changes in plaque geometry can, in turn, affect blood flow conditions. Thus, simultan...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-14016

    authors: Shimizu Y,Ohta M

    更新日期:2015-01-01 00:00:00

  • The influence of repair tissue maturation on the response to oscillatory compression in a cartilage defect repair model.

    abstract::This study examined the effects of mechanical compression on engineered cartilage in a novel hybrid culture system. Cylindrical holes were cut in discs of bovine articular cartilage and filled with agarose gels containing chondrocytes. These constructs were compressed in radiolabeled medium under static or oscillatory...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Hunter CJ,Levenston ME

    更新日期:2002-01-01 00:00:00

  • A structural viscoelastic model of soft tissues.

    abstract::A non-linear elastic model taking into account the microscopic structure of biological soft tissues is briefly presented and extended to quasi linear viscoelasticity. The modelling of the rheological behavior for near zero stress values is then discussed. ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1988-251-216

    authors: Flaud P,Quemada D

    更新日期:1988-01-01 00:00:00

  • Fission and refusion of red blood cells using a micropipette technique.

    abstract::In micropipette experiments with small capillaries and moderate high pressure difference (approximately 1000 Pa) cell fragmentation (fission) of human red blood cells without hemolysis was observed by TV-system for a large number of fresh red blood cells of different donors. After separation, the fragment moves away f...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1987-24302

    authors: Meier W,Lerche D,Wendt MO,Paulitschke M

    更新日期:1987-01-01 00:00:00

  • NMDA receptor expression and roles in human articular chondrocyte mechanotransduction.

    abstract::Mechanical forces influence articular cartilage structure by regulating chondrocyte activity. Mechanical stimulation results in activation of an alpha5beta1 integrin dependent intracellular signal cascade involving focal adhesion kinase and protein kinase C, triggering the release of interleukin-4 from the cell. In no...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Salter DM,Wright MO,Millward-Sadler SJ

    更新日期:2004-01-01 00:00:00

  • Influence of parenteral nutrition on blood rheology and platelet aggregation in vitro.

    abstract:BACKGROUND:Parenteral nutrition (PN) is a hyperosmolar solution composed of glucose, amino acids and a lipid emulsion, which is often used despite well-known side effects and complications. OBJECTIVES:In this study the hypothesis was tested that PN could affect hemorheology. METHODS:The influence of increasing plasma...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-140652

    authors: Compagnoni SC,Schulzki T,Thoeny S,Reinhart WH

    更新日期:2014-01-01 00:00:00

  • Structure of blood flow through a curved vessel with an aneurysm.

    abstract::A fine structure of blood flow through a curved vessel with an aneurysm was studied in in vitro experiments in relation to rheological factors of arterial diseases such as arteriosclerosis or thrombosis. On the basis of the in vivo data related to cerebral circulation, red blood cell suspension was flowed through curv...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1984-21418

    authors: Niimi H,Kawano Y,Sugiyama I

    更新日期:1984-01-01 00:00:00

  • Rheological effects of red blood cell aggregation in the venous network: a review of recent studies.

    abstract::It has long been recognized that understanding the rheological properties of blood is essential to a full understanding of the function of the circulatory system. Given the difficulty of obtaining carefully controlled measurements in vivo, most of our current concepts of the flow behavior of blood in vivo are based on...

    journal_title:Biorheology

    pub_type: 杂志文章,评审

    doi:

    authors: Bishop JJ,Popel AS,Intaglietta M,Johnson PC

    更新日期:2001-01-01 00:00:00

  • Developing red cell flow orientation shown by changes in blood reflectivity.

    abstract::The rate of onset of erythrocyte flow orientation at normal concentration has not previously been established. Reflectivity of blood and resuspended non-aggregated red cells at normal (41%) and elevated (60%) hematocrit has been used to examine this process. Video recordings were made before, during, and after shearin...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1988-25407

    authors: McMillan DE,Utterback NG,Lee MM

    更新日期:1988-01-01 00:00:00

  • The role of aggregation kinetics in the sedimentation of erythtocytes.

    abstract::The well-known S-shaped settling curves are obtained as solutions of an autonomic dynamical system deduced mathematically from the generalized Stokes formula, the blood volume conservation law, and the Smoluchowski theory of particle coagulation. Numerical computations and parametric analysis of the deduced two nonlin...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/0006-355x(96)00027-3

    authors: Petrov VG,Edissonov I

    更新日期:1996-07-01 00:00:00

  • Hemorheological effects of secoisolariciresinol in ovariectomized rats.

    abstract:BACKGROUND:Postmenopausal women often develop hemorheological disorders which may affect the systemic blood circulation and present a cardiovascular risk factor. OBJECTIVE:We evaluated effects of secoisolariciresinol (SECO), a phytoestrogen, on hemorheological parameters and lipid peroxidation in a model of the age-re...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-15066

    authors: Maslov MY,Plotnikova TM,Anishchenko AM,Aliev OI,Nifantiev NE,Plotnikov MB

    更新日期:2016-01-07 00:00:00

  • Computational study of the effect of geometric and flow parameters on the steady flow field at the rabbit aorto-celiac bifurcation.

    abstract::Arterial hemodynamic forces may play a role in the localization of early atherosclerotic lesions. We have been developing numerical techniques based on overset or "Chimera" type formulations to solve the Navier-Stokes equations in complex geometries simulating arterial bifurcations. This paper presents three-dimension...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/s0006-355x(99)80020-1

    authors: Cheer AY,Dwyer HA,Barakat AI,Sy E,Bice M

    更新日期:1998-11-01 00:00:00

  • Improvement of the microcirculation in the acute ischemic rat limb during intravenous infusion of drag-reducing polymers.

    abstract::Drag-reducing polymers (DRPs) are blood-soluble macromolecules that can increase blood flow and reduce vascular resistance. The purpose of the present study is to examine the effects of DRPs on microcirculation in rat hind limb during acute femoral artery occlusion. Two groups of 20 male Wistar rats were subjected to ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-2011-0592

    authors: Hu F,Zha D,Du R,Chen X,Zhou B,Xiu J,Bin J,Liu Y

    更新日期:2011-01-01 00:00:00

  • A numerical simulation of intimal thickening under shear in arteries.

    abstract::A model of intima thickening proposed by Friedman and his coworkers (1,2) is incorporated in our computer code to simulate the growth of intima under shear. The computer code is based on a finite volume method in a boundary-fitted coordinate system. It is found that the model yields an evenly-distributed thickening ov...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1992-292-312

    authors: Lee D,Chiu JJ

    更新日期:1992-03-01 00:00:00

  • Study of red cell aggregation in pulsatile flow from ultrasonic Doppler power measurements.

    abstract::Human red cell aggregability and disaggregability represent important hemorheological parameters of blood. Several techniques have been proposed to evaluate the tendency of red cells to form aggregates and to disrupt in the presence of shear stress. One of the most recent approaches is based on the characterization of...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1993-305-615

    authors: Cloutier G,Shung KK

    更新日期:1993-09-01 00:00:00