MRI and CT findings in Krabbe disease.

abstract：:According to increasing evidence, hypothermia can significantly improve outcomes in term neonates manifesting asphyxic insult and hypoxic-ischemic encephalopathy. Oxidative stress plays a key role in hypoxic-ischemic and inflammatory brain injuries. We investigated the impact of hypothermia on oxidative stress in babi...

journal_title：Pediatric neurology

authors： Perrone S,Szabó M,Bellieni CV,Longini M,Bangó M,Kelen D,Treszl A,Negro S,Tataranno ML,Buonocore G

更新日期：2010-10-01 00:00:00

abstract：:We describe eight cases of pediatric patients whose neuroimages performed after seizures revealed abnormalities that were compatible with edema surrounding calcified lesions and which disappeared in subsequent examinations. ...

journal_title：Pediatric neurology

authors： Antoniuk SA,Bruck I,Dos Santos LH,Pintarelli VL,Navolar FB,Brackmann PC Jr,de Morais RL

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Blepharophimosis-ptosis-epicanthus inversus syndrome is an autosomal dominant condition because of mutations or deletions of the FOXL2 gene. Microcephaly is not associated with FOXL2 mutations but has been reported in individuals with chromosome 3q deletions, which include the FOXL2 gene and other contiguous...

journal_title：Pediatric neurology

authors： Dean SJ,Holden KR,Dwivedi A,Dupont BR,Lyons MJ

更新日期：2014-06-01 00:00:00

abstract：:Brain plasticity refers to its ability to recover after damage. Visual field plasticity is not well recognized. We report a 12-year-old female who first presented with recurrent seizures and was subsequently found to have a large, right occipital cortical dysplasia on magnetic resonance imaging. Her visual field by Go...

journal_title：Pediatric neurology

authors： Kong CK,Wong LY,Yuen MK

更新日期：2000-09-01 00:00:00

abstract：:Tic disorders constitute a neurodevelopmental disorder of childhood. This study sought to determine the prevalence of tic disorders in a school-based sample. A randomized sample of 1158 schoolchildren, based on clusters (classrooms) in the province of Burgos (Spain), was identified on a stratified sampling frame combi...

journal_title：Pediatric neurology

authors： Cubo E,Gabriel y Galán JM,Villaverde VA,Velasco SS,Benito VD,Macarrón JV,Guevara JC,Louis ED,Benito-León J

更新日期：2011-08-01 00:00:00

abstract：:A retrospective review of children with epilepsy and obstructive sleep apnea, treated surgically for their obstructive sleep apnea from January 2008-October 2010, was performed for age, sex, type of epilepsy, antiseizure medications, sleep-study data, and changes in seizure frequency. Twenty-seven subjects (median age...

journal_title：Pediatric neurology

authors： Segal E,Vendrame M,Gregas M,Loddenkemper T,Kothare SV

更新日期：2012-06-01 00:00:00

abstract：:Leigh syndrome is an inherited, progressive neurodegenerative disorder of infancy and childhood. Mutations in the nuclear SURF-1 gene are specifically associated with cytochrome C oxidase-deficient Leigh syndrome. This report describes two patients with similar facial features. One of them was a 2(1/2)-year-old male, ...

journal_title：Pediatric neurology

authors： Yüksel A,Seven M,Cetincelik U,Yeşil G,Köksal V

更新日期：2006-06-01 00:00:00

abstract：:The most effective method for the screening and monitoring of optic pathway gliomas in children with neurofibromatosis type 1 remains a dilemma. Children less than 6 years of age are the group at highest risk for the development of optic pathway gliomas. Although an annual ophthalmologic examination currently is recom...

journal_title：Pediatric neurology

authors： Ng YT,North KN

更新日期：2001-01-01 00:00:00

abstract：:The clinical spectrum of the congenital muscular dystrophies is reviewed using as a sample population 10 Sicilian patients with various clinical subtypes. A comprehensive classification scheme for the muscular dystrophies is presented based on recent advances in our understanding of this heterogeneous group of syndrom...

journal_title：Pediatric neurology

authors： Parano E,Pavone L,Fiumara A,Falsaperla R,Trifiletti RR,Dobyns WB

更新日期：1995-09-01 00:00:00

abstract：:A young child with Hallervorden-Spatz syndrome is presented. She was well until 8 years of age when she lost interest in activities and her school performance declined. At age 11 years, she began having episodes of blepharospasm, accompanied by bilateral ptosis and occasional episodes of oculogyric crisis. By age 12 y...

journal_title：Pediatric neurology

authors： Zupanc ML,Chun RW,Gilbert-Barness EF

更新日期：1990-09-01 00:00:00

abstract：:Relapsing neuromyelitis optica is rare in children. The identification of a highly specific serum autoantibody marker (neuromyelitis optica-immunoglobulin G) differentiates neuromyelitis optica from other demyelinating disorders, particularly in clinically challenging cases. We present a child with multiple episodes o...

journal_title：Pediatric neurology

authors： Loma IP,Asato MR,Filipink RA,Alper G

更新日期：2008-09-01 00:00:00

abstract：:Nocturnal frontal-lobe epilepsy is characterized by paroxysmal arousals, motor seizures with dystonic or hyperkinetic features, and episodic nocturnal wanderings. Carbamazepine is effective for seizure control in some of these patients, but seizures may be refractory to multiple antiepileptic drugs. We report on eight...

journal_title：Pediatric neurology

authors： Raju GP,Sarco DP,Poduri A,Riviello JJ,Bergin AM,Takeoka M

更新日期：2007-11-01 00:00:00

abstract：:About 5-10% of school-age children manifest migraine headaches. Treatment options for pediatric migraine are limited. Topiramate is approved for migraine prophylaxis in adults, but its use in children is limited. We retrospectively reviewed the records of 37 patients, i.e., 22 (60%) girls and 15 (40%) boys (mean age, ...

journal_title：Pediatric neurology

authors： Cruz MJ,Valencia I,Legido A,Kothare SV,Khurana DS,Yum S,Hardison HH,Melvin JJ,Marks HG

更新日期：2009-09-01 00:00:00

abstract：:Fenfluramine therapy has been reported to improve behavior in infantile autism and has been associated with a decrease in abnormally increased blood serotonin content. The primary central effect has not been proved to be serotonergic. Beta-endorphin is involved in the anorexic effect of fenfluramine and may play a rol...

journal_title：Pediatric neurology

authors： Ross DL,Klykylo WM,Hitzemann R

更新日期：1987-03-01 00:00:00

abstract：:This study used xenon 133 inhalation and single-photon computed tomography to measure regional cerebral blood flow during a quiet resting condition, a simple auditory task, and an auditory phonemic discrimination task in 3 age-matched groups of children suffering from developmental language disabilities: expressive dy...

journal_title：Pediatric neurology

authors： Tzourio N,Heim A,Zilbovicius M,Gerard C,Mazoyer BM

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:No therapies have been formally approved by the Food and Drug Administration for use in pediatric multiple sclerosis, a rare disease. OBJECTIVE:We evaluated the safety, efficacy, and pharmacokinetics of dimethyl fumarate in pediatric patients with multiple sclerosis. METHODS:FOCUS, a phase 2, multicenter s...

journal_title：Pediatric neurology

authors： Alroughani R,Das R,Penner N,Pultz J,Taylor C,Eraly S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Posterior ischemic optic neuropathy results from ischemia of the retrobulbar aspect of the optic nerve. It presents as acute loss of vision without optic disc swelling. This is rare in children, with only seven cases reported to date. Neuroimaging is frequently used to aid in the diagnosis of acute visual co...

journal_title：Pediatric neurology

authors： Harrar DB,Solomon J,Shah AS,Vaughn J,Durbin AD,Rivkin MJ

更新日期：2018-07-01 00:00:00

abstract：:Two visually impaired children with occipital infarctions are presented. One patient has profound impairment of his primary visual pathway but has good vision for traveling, while the other child presented with the symptoms in reverse. We believe that these two patients provide further evidence that the primary visual...

journal_title：Pediatric neurology

authors： Jan JE,Wong PK,Groenveld M,Flodmark O,Hoyt CS

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Throughout the Middle Ages, most representations of the brain amounted to highly schematized ventricles housed within abstract squiggles of neural tissue. The works by the pre-eminent Flemish anatomist Andreas Vesalius in his De Humani Corporis Fabrica (1543) added considerably more accuracy and detail; stil...

journal_title：Pediatric neurology

authors： Sutherland-Foggio H

更新日期：2017-10-01 00:00:00

abstract：:In clinical practice, an association is commonly suggested between nocturnal epileptiform activity and language disorders in children. However, this association has not been studied systematically. This study explored the correlation between daily and nocturnal epileptiform discharges ratio, frequency of nocturnal epi...

journal_title：Pediatric neurology

authors： Overvliet GM,Besseling RM,Vles JS,Hofman PA,van Hall MH,Backes WH,Aldenkamp AP

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Autopsy studies in Rasmussen encephalitis reveal areas of sparing within the affected hemisphere. Clinical progression and inflammation are milder with an older onset. We sought to demonstrate radiological corroboration for these patterns. METHODS:In our retrospective study, 38 cases were dichotomized into ...

journal_title：Pediatric neurology

authors： Benjamin RN,Thomas M,Muthusamy K,Yoganathan S,Mathew V,Chacko AG,Prabhu K,Chacko G

更新日期：2020-11-01 00:00:00

abstract：:We report a 4-year-old, left-handed male with focal coxsackievirus A3 encephalitis who presented with seizures and acquired aphasia. Electroencephalography exhibited focal spike discharges over the right frontal regions, but cranial magnetic resonance imaging did not reveal any structural abnormalities. However, brain...

journal_title：Pediatric neurology

authors： Wakamoto H,Ohta M,Nakano N,Kunisue K

更新日期：2000-11-01 00:00:00

abstract：:We report on the successful use of electroconvulsive therapy in a 13-year-old boy with congenital hydrocephalus, a history of multiple shunt revisions, and a stable prepontine arachnoid cyst, who experienced profound catatonic deterioration. After initial shunt placement at age 20 months, the patient had followed norm...

journal_title：Pediatric neurology

authors： Wachtel LE,Baranano K,Reti IM

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Exome sequencing has recently been proved to be a successful diagnostic method for complex neurodevelopmental disorders. However, the diagnostic yield of exome sequencing for autism spectrum disorders has not been extensively evaluated in large cohorts to date. MATERIALS AND METHODS:We performed diagnostic ...

journal_title：Pediatric neurology

authors： Rossi M,El-Khechen D,Black MH,Farwell Hagman KD,Tang S,Powis Z

更新日期：2017-05-01 00:00:00

abstract：:Cerebral cavernous malformations are the second most common vascular malformations in the central nervous system, and over one-third are found in children. Lesions may be solitary or multiple, be discovered incidentally, be sporadic, or be secondary to familial cavernomatosis or radiation therapy. Children may present...

journal_title：Pediatric neurology

authors： Paddock M,Lanham S,Gill K,Sinha S,Connolly DJA

更新日期：2020-11-27 00:00:00

abstract：:This study assessed the utility of rectal diazepam gel in the home management of prolonged or repetitive seizures in children. Thirty-eight children being prescribed rectal diazepam gel by their clinician were prospectively recruited. Seizures, rectal diazepam use, emergency department visits, and quality of life data...

journal_title：Pediatric neurology

authors： O'Dell C,Shinnar S,Ballaban-Gil KR,Hornick M,Sigalova M,Kang H,Moshé SL

更新日期：2005-09-01 00:00:00

abstract：:Mitochondrial oxidation of a variety of substrates produces the bulk of energy requirements for most cell types. Impairment of oxidative metabolism may result in a broad spectrum of clinical signs and symptoms. A disorder of oxidative metabolism should be suspected when an unexplained association of signs and symptoms...

journal_title：Pediatric neurology

authors： Breningstall GN

更新日期：1993-03-01 00:00:00

abstract：:Epileptic activity, as a component of epileptic encephalopathies, can interfere with brain growth and development. Infantile spasms as a syndrome represent such epileptic activity during the period of spasms and hypsarrhythmia. The rate of head growth in infants with infantile spasms during the period of spasms has no...

journal_title：Pediatric neurology

authors： Rener-Primec Z,Lozar-Krivec J,Krivec U,Neubauer D

更新日期：2006-09-01 00:00:00

abstract：:The details of 328 patients with bacterial meningitis, admitted from 1984 through 1993, were obtained from 46 departments of pediatrics of large hospitals through questionnaires. The incidence rate per 100,000 child-years was 2.32, being higher in children aged 0-4 years (rate, 7.22) than 5-15 years (rate, 0.49). The ...

journal_title：Pediatric neurology

authors： Ishikawa T,Asano Y,Morishima T,Nagashima M,Sobue G,Watanabe K,Yamaguchi H

更新日期：1996-04-01 00:00:00

abstract：:Neuroblastoma associated with the paraneoplastic syndrome of opsoclonus-myoclonus is well-described. However, presentation with narcolepsy-cataplexy is not well-documented in the literature. Narcolepsy with cataplexy is also rare in children younger than 5 years of age. Here we describe three patients, each presenting...

journal_title：Pediatric neurology

authors： Sinsioco C,Silver K,Forrest KM,Gray J,Nechay A,Sheldon S,Chelmicka Schorr E

更新日期：2013-07-01 00:00:00