Role of the colon in short bowel syndrome and intestinal transplantation.

Abstract:

:Colon is a crucial partner for small intestinal adaptation and function in patients who underwent extensive small intestinal resection or transplantation. This short review deals with the different properties and roles of the colon in these settings, involving fluid and electrolytes absorption, absorption of medium-chain triglycerides, and production of short-chain fatty acids for malabsorbed energy salvage. The colon may adapt after small intestinal resection, whereas it hosts the most important part of the intestinal microbiota, which plays a crucial role in intestinal function and health. Also, colon may be responsible for D-lactic acidosis as well, as it can be injured by noninfectious colitis. Finally, the relevance of a simultaneous colon grafting is discussed as it is occasionally considered in specific patients requiring intestinal transplantation.

authors

Goulet O,Colomb-Jung V,Joly F

doi

10.1097/MPG.0b013e3181a118ef

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

S66-71

eissn

0277-2116

issn

1536-4801

pii

00005176-200904002-00010

journal_volume

48 Suppl 2

pub_type

杂志文章,评审
  • Evaluation and treatment of constipation in children: summary of updated recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

    abstract::Constipation is a common pediatric problem. To assist health care professionals who care for children with constipation, the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) previously published a clinical guideline based on an integration of medical evidence with expert opini...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,实务指引,评审

    doi:10.1097/01.mpg.0000232574.41149.0a

    authors: North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

    更新日期:2006-09-01 00:00:00

  • Fecal secretory immunoglobulin A in breast milk versus formula feeding in early infancy.

    abstract::We studied the effects of breast milk feeding versus formula feeding during the first 8 weeks of life on the development of local gastrointestinal humoral immune response by measuring fecal secretory immunoglobulin A (SIgA). Forty-four infants were studied and classified into two groups: breast milk (n = 21) and stand...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:

    authors: Koutras AK,Vigorita VJ

    更新日期:1989-07-01 00:00:00

  • Impact of early dietary intake and blood lipid composition of long-chain polyunsaturated fatty acids on later visual development.

    abstract:BACKGROUND:In contrast to human milk, current infant formulas in the United States do not contain omega3 and omega6 long-chain polyunsaturated fatty acids. This may lead to suboptimal blood lipid fatty acid profiles and to a measurable diminution of visual function in developing term infants. The need for docosahexaeno...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00005176-200011000-00016

    authors: Hoffman DR,Birch EE,Birch DG,Uauy R,Castañeda YS,Lapus MG,Wheaton DH

    更新日期:2000-11-01 00:00:00

  • Tryptophan fortification of adapted formula increases plasma tryptophan concentrations to levels not different from those found in breast-fed infants.

    abstract::Several recent studies have demonstrated significantly lower plasma total tryptophan concentrations in formula-fed than in breast-fed infants. We have measured preprandial plasma amino acid concentrations in infants breast-fed or fed a formula with a protein concentration of 1.57 g/dl and with a whey/casein ratio of 6...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00005176-199205000-00014

    authors: Fazzolari-Nesci A,Domianello D,Sotera V,Räihä NC

    更新日期:1992-05-01 00:00:00

  • Evaluation of oral rehydration solution by whole-gut perfusion in rats: effect of osmolarity, sodium concentration and resistant starch.

    abstract:BACKGROUND:Reduced osmolarity oral rehydration solution (ORS) improved small bowel absorption of fluid and electrolytes in segmental perfusion in experimental animals; this was borne out in clinical practice. Adding amylase-resistant starch (RS) to ORS is expected to increase colonic fluid absorption. This study used c...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/01.mpg.0000239998.43141.b2

    authors: Subramanya S,Ramakrishna BS,Binder HJ,Farthing MJ,Young GP

    更新日期:2006-11-01 00:00:00

  • Golimumab Therapy in Six Patients With Severe Pediatric Onset Crohn Disease.

    abstract::Anti-tumor necrosis factor-alpha (TNF-α) blockade is so far the most effective therapy for extensive pediatric Crohn disease (CD), but loss of response is frequently encountered. We describe here the use of golimumab (Simponi) in 6 pediatric CD patients with antibody formation/loss of response to infliximab and adalim...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000001165

    authors: Merras-Salmio L,Kolho KL

    更新日期:2016-09-01 00:00:00

  • Guidance for clinical trials for children and adolescents with chronic hepatitis C.

    abstract::Most children with chronic hepatitis C are infected vertically, have a low natural seroconversion rate, and carry a lifetime risk of cirrhosis and cancer. Affected children are usually asymptomatic, and histological findings are mild with a low risk of progression, although 5% develop significant liver disease in chil...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3181f6f09c

    authors: Wirth S,Kelly D,Sokal E,Socha P,Mieli-Vergani G,Dhawan A,Lacaille F,Saint Raymond A,Olivier S,Taminiau J

    更新日期:2011-02-01 00:00:00

  • Protein synthesis by gastric mucosal ribosomes during development in rats.

    abstract::Oxyntic gland mucosal ribosomes from 7- to 30-day-old rats were assayed for their ability to synthesize endogenous messenger RNA (mRNA) and poly(U)-directed protein in a cell-free system. Normal rat liver cell sap (105,000 g supernatant) was used as a source for transfer RNA (tRNA) and activating enzymes. Total mucosa...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198401000-00024

    authors: Majumdar AP

    更新日期:1984-01-01 00:00:00

  • Immunoglobulin levels in human colostrum and milk.

    abstract::The levels of secretory IgA and of IgM and IgG in colostrums and milks obtained at various times postpartum were measured by radial immunodiffusion. Immunoglobulin A was the dominant immunoglobulin in all samples, and concentrations in colostrum ranged from 1.5 to 83.7 g/L (mean 32 g/L). Immunoglobulin M and IgG had m...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198201030-00018

    authors: Mickleson KN,Moriarty KM

    更新日期:1982-01-01 00:00:00

  • Even small amounts of gluten cause relapse in children with celiac disease.

    abstract:BACKGROUND:Previously, a gluten challenge was customary to establish the diagnosis of celiac disease in children. There are no clear recommendations on how to perform this challenge or what markers to rely on for timing the biopsy after the challenge. The authors' aim was to monitor gluten intake, clinical symptoms, an...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-200201000-00007

    authors: Laurin P,Wolving M,Fälth-Magnusson K

    更新日期:2002-01-01 00:00:00

  • Perceptions of gender equality in work-life balance, salary, promotion, and harassment: results of the NASPGHAN task force survey.

    abstract:OBJECTIVES:Gender equality in the workplace has not been described in pediatric gastroenterology. METHODS:An electronic survey that explored perceptions of career parity, work-life balance, and workplace harassment was sent to all members of the North American Society for Pediatric Gastroenterology, Hepatology, and Nu...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000000637

    authors: Tomer G,Xanthakos S,Kim S,Rao M,Book L,Litman HJ,Fishman LN

    更新日期:2015-04-01 00:00:00

  • Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial.

    abstract:BACKGROUND:The probiotic Lactobacillus GG is effective in promoting a more rapid recovery of acute, watery diarrhea in children with rotavirus enteritis. Very limited information is available, however, on the potential role of such agents in non-rotaviral diarrheal episodes. Furthermore, no evidence is available concer...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00005176-200001000-00018

    authors: Guandalini S,Pensabene L,Zikri MA,Dias JA,Casali LG,Hoekstra H,Kolacek S,Massar K,Micetic-Turk D,Papadopoulou A,de Sousa JS,Sandhu B,Szajewska H,Weizman Z

    更新日期:2000-01-01 00:00:00

  • Biliary atresia in Canada: the effect of centre caseload experience on outcome.

    abstract:OBJECTIVES:: Biliary atresia (BA) is a leading cause of end-stage paediatric liver disease. Standard BA treatment is sequential surgery with an initial Kasai procedure (KP) followed by liver transplant (LT) for patients who progress to liver failure. A key determinant for the post-KP patient survival with their native ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e3181d67e5e

    authors: Schreiber RA,Barker CC,Roberts EA,Martin SR,Canadian Pediatric Hepatology Research Group.

    更新日期:2010-07-01 00:00:00

  • Expression of microbiota, Toll-like receptors, and their regulators in the small intestinal mucosa in celiac disease.

    abstract:OBJECTIVES:Less than one-tenth of the carriers of the risk genes HLA-DQ2 or HLA-DQ8 develop celiac disease, suggesting that other genetic and environmental factors are important in the pathogenesis. The role of gut microbiota has been addressed previously with inconsistent findings. Our aim was to evaluate microbiota, ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e318241cfa8

    authors: Kalliomäki M,Satokari R,Lähteenoja H,Vähämiko S,Grönlund J,Routi T,Salminen S

    更新日期:2012-06-01 00:00:00

  • Restitution of swallowing in the fetal sheep restores intestinal growth after midgestation esophageal obstruction.

    abstract::We have shown that, in the fetal sheep, abolition of fluid ingestion early in gestation results in a profound gastrointestinal tract (GIT)-specific growth retardation and that these effects can be reversed if fetal swallowing is restored, even for relatively short periods (15 days). The fetal esophagus was ligated at ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-199502000-00004

    authors: Trahair JF,Harding R

    更新日期:1995-02-01 00:00:00

  • Mass Screening for Celiac Disease Among School-aged Children: Toward Exploring Celiac Iceberg in Saudi Arabia.

    abstract:OBJECTIVES:We conducted this mass screening study to determine the prevalence of celiac disease (CD) and characterize the celiac iceberg among Saudi pediatric population in Riyadh, the capital city of Saudi Arabia. METHODS:During the study period (January 2014-June 2016), we have conducted a cross-sectional, mass scre...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000001681

    authors: Al-Hussaini A,Troncone R,Khormi M,AlTuraiki M,Alkhamis W,Alrajhi M,Halal T,Fagih M,Alharbi S,Bashir MS,Chentoufi AA

    更新日期:2017-12-01 00:00:00

  • Effect of ursodeoxycholic acid therapy on hepatic function in children with intrahepatic cholestatic liver disease.

    abstract:BACKGROUND:Ursodeoxycholic acid (UDCA) has been shown to improve pruritus, alanine aminotransferase (ALT), and cholesterol levels in children with intrahepatic cholestatic liver disease. However, the effect of UDCA on quantitative tests of hepatic function in children is uncertain. METHODS:A 2.5-year, open label, cros...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 临床试验,杂志文章

    doi:10.1097/00005176-199801000-00009

    authors: Narkewicz MR,Smith D,Gregory C,Lear JL,Osberg I,Sokol RJ

    更新日期:1998-01-01 00:00:00

  • Transient protein-losing hypertrophic gastropathy associated with Mycoplasma pneumoniae infection in childhood.

    abstract::A 3-year-old boy with transient protein loss due to hypertrophic gastropathy is described. Serologic evidence of concomitant Mycoplasma pneumoniae infection was present. Although sometimes associated with infections, protein-losing hypertrophic gastropathy has not been reported previously in association with Mycoplasm...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-199202000-00021

    authors: Ben Amitai D,Zahavi I,Dinari G,Garty BZ

    更新日期:1992-02-01 00:00:00

  • Wilson's disease associated with pancreatitis.

    abstract::A 12-year-old boy presented with a 2-month history of abdominal pain and distention. A diagnosis of Wilson's disease was established, and D-penicillamine therapy was initiated. An associated pancreatitis was diagnosed on presentation, based on elevated serum amylase and an enlarged pancreas ultrasonically. Subsequentl...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198811000-00024

    authors: Weizman Z,Picard E,Barki Y,Moses S

    更新日期:1988-11-01 00:00:00

  • Serum transaminases in children with Wilson's disease.

    abstract:OBJECTIVES:The response of serum transaminase levels to penicillamine and zinc treatment in Wilson's disease is poorly understood. The aim of this multicenter retrospective study was to evaluate transaminase levels after penicillamine and zinc treatment in children with Wilson's disease. PATIENTS AND METHODS:One hundr...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-200410000-00006

    authors: Iorio R,D'Ambrosi M,Marcellini M,Barbera C,Maggiore G,Zancan L,Giacchino R,Vajro P,Marazzi MG,Francavilla R,Michielutti F,Resti M,Frediani T,Pastore M,Mazzarella G,Fusco G,Cirillo F,Vegnente A,Hepatology Committee of

    更新日期:2004-10-01 00:00:00

  • Brain maturation of preterm newborn babies: new insights.

    abstract::Preterm birth still results in a high number of neurodevelopmental sequelae, although major forms of brain lesions--such as periventricular leukomalacia and intraventricular hemorrhage--are significantly reduced in this population of babies compared with a few years ago. This paper focuses on the possible reasons for ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/01.mpg.0000302960.63052.fa

    authors: Ramenghi LA,Fumagalli M,Bassi L,Groppo M,De Carli A,Fanaro S,Mosca F

    更新日期:2007-12-01 00:00:00

  • Effects of cytochalasin B on the synthesis and secretion of plasma proteins by developing rat liver.

    abstract::Antimicrotubular drugs such as colchicine impair plasma protein secretion markedly less from developing liver than from mature tissue, suggesting the reduced participation of microtubules in hepatic protein secretion during liver development. In order to evaluate the possible contribution of microfilaments to protein ...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198801000-00020

    authors: Kaufman SS,Tuma DJ,Park JH,Grandjean CJ

    更新日期:1988-01-01 00:00:00

  • Clinical safety of Lactobacillus casei shirota as a probiotic in critically ill children.

    abstract:OBJECTIVE:Diarrhea is frequently observed among critically ill children (CIC) admitted for intensive care. There is increasing evidence that probiotics decrease the incidence of acute infectious and nosocomial and antibiotic induced diarrhea amongst children hospitalized in nonintensive care settings. Despite theoretic...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.mpg.0000189335.62397.cf

    authors: Srinivasan R,Meyer R,Padmanabhan R,Britto J

    更新日期:2006-02-01 00:00:00

  • Re-treatment of children with chronic hepatitis C who did not respond to interferon-alpha treatment.

    abstract:BACKGROUND:Many patients with chronic hepatitis C do not respond to antiviral treatment. In adult patients the re-treatment of these patients has been extensively investigated. Because the response to re-treatment in children is not well defined we evaluated the efficacy and safety of interferon (IFN)-alpha plus ribavi...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 临床试验,杂志文章

    doi:10.1097/MPG.0b013e3181d9c7f6

    authors: Gerner P,Hilbich J,Wenzl TG,Behrens R,Walther F,Kliemann G,Enninger A,Wirth S

    更新日期:2010-08-01 00:00:00

  • Critical role for P-glycoprotein expression in hematopoietic cells in the FVB.Mdr1a(-/-) model of colitis.

    abstract:OBJECTIVE:P-glycoprotein (P-gp), the functional product of the multidrug resistance gene (MDR), is a transmembrane protein that extrudes substrates from the intracellular environment. P-gp is expressed on the apical surface of epithelial cells and on cells from the hematopoietic lineage. Human MDR polymorphisms have be...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0b013e31822860f1

    authors: Staley EM,Dimmitt RA,Schoeb TR,Tanner SM,Lorenz RG

    更新日期:2011-12-01 00:00:00

  • Timing of the gut closure.

    abstract::This study was designed to establish whether the starting time of breast-feeding (BF) may have affected gut closure for macromolecules during the earliest postnatal period. An increase of serum IgA concentrations was taken as the index of gut permeability to macromolecules. In 14 neonates, BF started 1-6 h after birth...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198411000-00011

    authors: Vukavić T

    更新日期:1984-11-01 00:00:00

  • Diagnosis of Helicobacter pylori infection by means of reduced-dose ¹³C-urea breath test and early sampling of exhaled breath.

    abstract:OBJECTIVE:The aim of this study was to evaluate the accuracy of reduced-dose ¹³C-urea breath test (¹³C-UBT) and early sampling of exhaled breath for the detection of Helicobacter pylori infection in children and adolescents. METHODS:Patients up to 20 years old that underwent upper gastrointestinal endoscopy with gastr...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MPG.0b013e3182a02608

    authors: Pacheco SL,Ogata SK,Machado RS,Patrício FR,Pardo ML,Kawakami E

    更新日期:2013-11-01 00:00:00

  • Milk composition of insulin-dependent diabetic women.

    abstract::The macronutrient, trace mineral, and immunological contents of milk of five moderately controlled, insulin-dependent diabetic women were studied at 3 months postpartum. Concentrations of total nitrogen, lactose, fat, and energy were not distinguishable from those in milk of nondiabetic women. Glucose concentrations i...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/00005176-198711000-00020

    authors: Butte NF,Garza C,Burr R,Goldman AS,Kennedy K,Kitzmiller JL

    更新日期:1987-11-01 00:00:00

  • "Let there be bile"--understanding hepatic injury in cholestasis.

    abstract::Cholestatic liver disorders account for a large proportion of chronic liver ailments in adults, children and infants, and are among the leading indications for liver transplantation in all age groups. Recent studies have begun to characterize the cellular and molecular mechanisms of hepatocyte injury caused by the ret...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章,评审

    doi:10.1097/01.mpg.0000226384.71859.16

    authors: Sokol RJ,Devereaux M,Dahl R,Gumpricht E

    更新日期:2006-07-01 00:00:00

  • Repeatability of gastric volume measurements and intragastric content using ultrasound in preterm infants.

    abstract:OBJECTIVES:The aim of the present study was to determine whether serial gastric volumes and intragastric curding are repeatable within individual preterm infants when given sequential feeds of the same volume and composition. Infant and feeding characteristics that may influence differences in measured gastric volumes,...

    journal_title:Journal of pediatric gastroenterology and nutrition

    pub_type: 杂志文章

    doi:10.1097/MPG.0000000000000397

    authors: Perrella SL,Hepworth AR,Simmer KN,Hartmann PE,Geddes DT

    更新日期:2014-08-01 00:00:00