Neonatal seizures: do they damage the brain?

abstract：BACKGROUND:Acute cerebellitis is a rare inflammatory syndrome in children, with either infectious or autoimmune etiologies. PATIENT:We describe a 7-year-old girl with a presentation of cerebellitis following group A streptococcal infection. RESULTS:Magnetic resonance imaging showed diffuse symmetrical swelling and ed...

journal_title：Pediatric neurology

authors： Uchizono H,Iwasa T,Toyoda H,Takahashi Y,Komada Y

更新日期：2013-12-01 00:00:00

abstract：:Hashimoto encephalopathy is a rare, clinically heterogenous condition. Its treatment is based on corticosteroids. A previously normal 12-year-old boy was admitted to our pediatric emergency department with status epilepticus. He experienced a recurrence of status epilepticus after pentobarbital withdrawal, and require...

journal_title：Pediatric neurology

authors： Bektas Ö,Yılmaz A,Kendirli T,Sıklar Z,Deda G

更新日期：2012-02-01 00:00:00

abstract：:It was the purpose of this study to compare the efficacy and side effects of lamotrigine (LTG) and vigabatrin (VGB) as add-on therapy in epilepsies of childhood resistant to conventional drugs. Retrospective analysis of the medical charts and electroencephalograms of 134 children (LTG 57, VGB 77) was performed conside...

journal_title：Pediatric neurology

authors： Dimova PS,Korinthenberg R

更新日期：1999-11-01 00:00:00

abstract：:We report the clinical features and the muscle pathology in 2 patients with congenital muscular dystrophy (CMD) secondary to merosin deficiency and in 2 patients with sarcoglycan (adhalin) deficiency. Electron microscopic examination revealed sarcolemmal defects in non-necrotic muscle fibers in all cases. These pathol...

journal_title：Pediatric neurology

authors： Fadic R,Waclawik AJ,Lewandoski PJ,Lotz BP

更新日期：1997-01-01 00:00:00

abstract：:Dandy-Walker cyst associated with occipital meningocele is very rare. Only 12 patients have been reported. We report a female infant with Dandy-Walker cyst and occipital meningocele whose diagnosis was suspected antenatally by in utero ultrasonography. At birth, head circumference was normal for 37 weeks gestation. Sh...

journal_title：Pediatric neurology

authors： Suzuki Y,Mimaki T,Tagawa T,Seino Y,Ohmichi M,Sugita N,Morimoto K,Yoshimine T

更新日期：1989-05-01 00:00:00

abstract：:We report a 13-year-old female who experienced symptoms and signs of Rasmussen encephalitis for the first time at the age of 5 years. Various therapeutic procedures, including conventional and new antiepileptic drugs, steroids, immunoglobulin, plasma exchanges, and partial hemispherectomy, were applied, but their resu...

journal_title：Pediatric neurology

authors： Marjanovic BD,Stojanov LM,Zdravkovic DS,Kravljanac RM,Djordjevic MS

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Patients in China with juvenile-onset myasthenia gravis present early, with a high prevalence of purely ocular symptoms, spontaneous remission rates, and low antibody seropositivity. Antibody detection using a cell-based assay has been reported to increase the diagnostic sensitivity in adult-onset myasthenia...

journal_title：Pediatric neurology

authors： Yan C,Li W,Song J,Feng X,Xi J,Lu J,Zhou S,Zhao C

更新日期：2019-09-01 00:00:00

abstract：:Despite significant improvement in mortality rate, survivors of neonatal bacterial meningitis experience a significant incidence of neurodevelopmental sequelae. Neuropathologic studies have demonstrated vasculitis, arachnoiditis, and ventriculitis with secondary edema and encephalomalacia. Areas of cerebral infarction...

journal_title：Pediatric neurology

authors： Ment LR,Ehrenkranz RA,Duncan CC

更新日期：1986-09-01 00:00:00

abstract：:As part of the implementation of a population-based registry of children with cerebral palsy, caregiver satisfaction with the process by which diagnosis was originally communicated by a professional was assessed. Satisfaction with various aspects of the diagnosis process was assessed using a five-point Likert scale an...

journal_title：Pediatric neurology

authors： Dagenais L,Hall N,Majnemer A,Birnbaum R,Dumas F,Gosselin J,Koclas L,Shevell MI

更新日期：2006-12-01 00:00:00

abstract：:Four children with self-inflicted strangulation injuries had cerebral blood flow determined by stable xenon computed tomography (XeCTCBF) within 24 hours of admission. All had suffered a severe hypoxic-ischemic cerebral injury; 3 initially had fixed pupils, all were apneic with varying bradyarrhythmias, and the initia...

journal_title：Pediatric neurology

authors： Ashwal S,Perkin RM,Thompson JR,Tomasi LG,van Stralen D,Schneider S

更新日期：1991-09-01 00:00:00

abstract：:A patient with X-linked adrenoleukodystrophy exhibited a phenotype of neurofibromatosis 1. He had large and multiple café-au-lait spots, and had elevated serum levels of very long chain fatty acids. The patient's mother and elder sister also had X-linked adrenoleukodystrophy. This case represents novel manifestations ...

journal_title：Pediatric neurology

authors： Yamada H,Izumi T

更新日期：2009-09-01 00:00:00

abstract：:In areas without expanded newborn screening, instead of presenting neonatally, patients with arginase deficiency typically present with spastic paraplegia in early childhood. Diagnosis of this rare neurometabolic disease poses the first challenge because it is often misdiagnosed as cerebral palsy during initial stages...

journal_title：Pediatric neurology

authors： Tsang JP,Poon WL,Luk HM,Fung CW,Ching CK,Mak CM,Lam CW,Siu TS,Tam S,Wong VC

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Sleep problems affect 30% to 80% of patients with mild traumatic brain injury. We assessed the prevalence of sleep disorders after mild traumatic brain injury and its correlation with other symptoms. METHODS AND MATERIALS:Individuals with mild traumatic brain injury were assessed at the New York University ...

journal_title：Pediatric neurology

authors： Tkachenko N,Singh K,Hasanaj L,Serrano L,Kothare SV

更新日期：2016-04-01 00:00:00

abstract：:This report describes a case of West Nile virus meningoencephalitis in a previously healthy adolescent. Clinical features included fever, altered mental status, and speech difficulty, with subsequent hyperesthesia, ataxia, and motor weakness, all of which eventually resolved completely. Magnetic resonance imaging was ...

journal_title：Pediatric neurology

authors： DeBiasi RL,Parsons JA,Grabert BE

更新日期：2005-09-01 00:00:00

abstract：:Clonidine is used as second-line medication for the treatment of attention deficit hyperactivity disorder in children. Product information concerning clonidine reported seizures only after overdosage of clonidine, and the prescription of clonidine has not been contraindicated in patients with known epilepsy. The prese...

journal_title：Pediatric neurology

authors： Feron FJ,Hendriksen JG,Nicolai J,Vles JS

更新日期：2008-02-01 00:00:00

abstract：:An 8-year-old boy was diagnosed with autism, along with development delay, seizures, and hypoplastic corpus callosum. His karyotype was 47, XY, +mar.ish (15) (D15Z1+, SNRPN+, GABRB3+, PML-(de novo?). The supernumerary marker chromosome 15 with euchromatin was monosatellited and monocentric. Although autism, seizures, ...

journal_title：Pediatric neurology

authors： Jovanović-Privrodski JD,Kavecan II,Obrenović MR,Buonadonna LA,Bukvić NM

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Nuclear polymerase gamma (POLG) mutations are the most common cause of inherited mitochondrial disease. POLG mutation diseases have a broad spectrum of clinical manifestations; the lethal infantile form is myocerebrohepatopathy spectrum. PATIENT:A 4-month-old boy was referred for poor feeding, emesis, failu...

journal_title：Pediatric neurology

authors： Horst DM,Ruess L,Rusin JA,Bartholomew DW

更新日期：2014-11-01 00:00:00

abstract：:Postictal psychosis is a state of psychosis following repeated or prolonged complex partial seizures with or without secondary generalization and is well described in adult epilepsy literature. It is sparsely reported in the pediatric literature. This report describes a 12-year-old male presenting with status epilepti...

journal_title：Pediatric neurology

authors： Joshi CN,Booth FA,Sigurdson ES,Bolton JM,Shah NS

更新日期：2006-05-01 00:00:00

abstract：:In a prospective study, we analyzed the intraoperative electroencephalographic (EEG) changes during open heart surgery with deep hypothermia in 66 infants aged 6 months or younger, 70% of whom were neonates. Suppression of amplitude and continuity at the nadir of temperature reduction and following rewarming, and the ...

journal_title：Pediatric neurology

authors： Miller G,Rodichok LD,Baylen BG,Myers JL

更新日期：1994-03-01 00:00:00

abstract：:Resting cerebral glucose metabolism was assessed by 18[F]-fluorodeoxyglucose in 11 Down syndrome patients. Standardized uptake values were determined on a pixel-by-pixel basis from the measured tissue-activity data. The results revealed a mean overall 18[F]-fluorodeoxyglucose uptake in the Down syndrome patients close...

journal_title：Pediatric neurology

authors： Lengyel Z,Balogh E,Emri M,Szikszai E,Kollár J,Sikula J,Esik O,Trón L,Oláh E

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Although cerebral palsy is reported to have a higher prevalence in low-resource settings, there are few studies describing risk factors for cerebral palsy in these settings. A better understanding of the unique risk factors affecting children with cerebral palsy in low-resource settings could optimize both r...

journal_title：Pediatric neurology

authors： Monokwane B,Johnson A,Gambrah-Sampaney C,Khurana E,Baier J,Baranov E,Westmoreland KD,Mazhani L,Steenhoff AP,Bearden DR

更新日期：2017-12-01 00:00:00

abstract：:Oxcarbazepine, a carbamazepine analog, was approved for use as an antiepileptic agent in the United States in 2000. A search of the United States Food and Drug Administration's Adverse Event Reporting System identified nine cases of oxcarbazepine-associated angioedema in pediatric patients aged 16 years and younger. W...

journal_title：Pediatric neurology

authors： Knudsen JF,Flowers CM,Kortepeter C,Awaad Y

更新日期：2007-08-01 00:00:00

abstract：:Melioidosis from Pseudomonas pseudomallei is common in endemic areas (particularly southeast Asia) and is being recognized with increasing frequency in developed countries. Central nervous system involvement is a rare complication with a high mortality. A patient with multiple cerebral abscesses caused by this organis...

journal_title：Pediatric neurology

authors： Pelekanos JT,Appleton DB

更新日期：1989-01-01 00:00:00

abstract：:Traumatic spinal epidural hematoma (TSEH) is rare in children. Only three cases of TSEH were documented in the pediatric literature. This clinical note presents an infant with TSEH but no risk factors. Without magnetic resonance imaging examination, children with TSEH and minor symptoms may be missed and under reporte...

journal_title：Pediatric neurology

authors： Alva NS

更新日期：2000-07-01 00:00:00

abstract：:Between 1991-2006, nine patients below age 18 years, with a microbiologic documentation of Cryptococcus neoformans infection and no evidence of human immunodeficiency virus infection, were identified and treated at Chang Gung Children's Hospital. All exhibited central nervous system involvement. Seven patients were fe...

journal_title：Pediatric neurology

authors： Huang KY,Huang YC,Hung IJ,Lin TY

更新日期：2010-04-01 00:00:00

abstract：:We report a boy 20 months of age with encephalopathy, petechiae, and ethylmalonic aciduria (EPEMA). Other clinical features were severe hypotonia, orthostatic acrocyanosis, and chronic diarrhea. Magnetic resonance imaging (MRI) of the brain demonstrated bilateral lesions in the lenticular and caudate nuclei, periaqued...

journal_title：Pediatric neurology

authors： García-Silva MT,Ribes A,Campos Y,Garavaglia B,Arenas J

更新日期：1997-09-01 00:00:00

abstract：:The ability to predict long-term neurologic and neuropsychologic outcomes in 22 children, ages 1 week to 14 years at the time of traumatic brain injury, was investigated using proton magnetic resonance spectroscopy acquired post injury and compared with standardized neurologic, intellectual, and neuropsychologic testi...

journal_title：Pediatric neurology

authors： Brenner T,Freier MC,Holshouser BA,Burley T,Ashwal S

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Blepharophimosis-ptosis-epicanthus inversus syndrome is an autosomal dominant condition because of mutations or deletions of the FOXL2 gene. Microcephaly is not associated with FOXL2 mutations but has been reported in individuals with chromosome 3q deletions, which include the FOXL2 gene and other contiguous...

journal_title：Pediatric neurology

authors： Dean SJ,Holden KR,Dwivedi A,Dupont BR,Lyons MJ

更新日期：2014-06-01 00:00:00

abstract：:An adolescent girl with systemic lupus erythematosus presented with selective brainstem dysfunction as the initial sign of central nervous system involvement. Although computed tomography was initially normal, magnetic resonance imaging demonstrated multiple, large brainstem lesions. Serial magnetic resonance imaging,...

journal_title：Pediatric neurology

authors： McAbee GN,Barasch ES

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Children with perinatal arterial ischemic stroke (PAIS) are at risk for later neurocognitive and behavioral deficits, yet the clinical predictors of these outcomes are understudied. We examined the influence of clinical and infarct characteristics on attention and executive functioning in children following ...

journal_title：Pediatric neurology

authors： Bosenbark DD,Krivitzky L,Ichord R,Vossough A,Bhatia A,Jastrzab LE,Billinghurst L

更新日期：2017-04-01 00:00:00