Hashimoto encephalopathy causing drug-resistant status epilepticus treated with plasmapheresis.

Abstract:

:Hashimoto encephalopathy is a rare, clinically heterogenous condition. Its treatment is based on corticosteroids. A previously normal 12-year-old boy was admitted to our pediatric emergency department with status epilepticus. He experienced a recurrence of status epilepticus after pentobarbital withdrawal, and required repeated resumptions of drug-induced coma. He manifested acute personality changes. His limbic encephalitis markers were normal, but his level of anti-thyroid peroxidase antibody was high. A diagnosis of Hashimoto encephalopathy was considered. Our patient responded to plasmapheresis instead of corticosteroid treatment. This case report is the first, to the best of our knowledge, of plasmapheresis because of Hashimoto encephalopathy in a child.

journal_name

Pediatr Neurol

journal_title

Pediatric neurology

authors

Bektas Ö,Yılmaz A,Kendirli T,Sıklar Z,Deda G

doi

10.1016/j.pediatrneurol.2011.11.009

subject

Has Abstract

pub_date

2012-02-01 00:00:00

pages

132-5

issue

2

eissn

0887-8994

issn

1873-5150

pii

S0887-8994(11)00470-X

journal_volume

46

pub_type

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