Bacterial meningitis as an etiology of perinatal cerebral infarction.

Abstract:

:Despite significant improvement in mortality rate, survivors of neonatal bacterial meningitis experience a significant incidence of neurodevelopmental sequelae. Neuropathologic studies have demonstrated vasculitis, arachnoiditis, and ventriculitis with secondary edema and encephalomalacia. Areas of cerebral infarction, most commonly thought to be venous in origin, have been reported as well. We performed cranial computed tomographic scans on all eight neonates with bacterial meningitis admitted to our Newborn Special Care Unit within the past 36 months and demonstrated abnormalities in seven. Six of these infants were found to have large areas of infarction related primarily to major arterial vascular distributions. We suggest computed tomographic studies for all neonates with bacterial meningitis and subsequent scans at 4-6 months of age in those with abnormal neonatal scans in order to plan better for early intervention services.

journal_name

Pediatr Neurol

journal_title

Pediatric neurology

authors

Ment LR,Ehrenkranz RA,Duncan CC

doi

10.1016/0887-8994(86)90019-6

subject

Has Abstract

pub_date

1986-09-01 00:00:00

pages

276-9

issue

5

eissn

0887-8994

issn

1873-5150

pii

0887-8994(86)90019-6

journal_volume

2

pub_type

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