Acute cerebellitis following hemolytic streptococcal infection.

Abstract:

BACKGROUND:Acute cerebellitis is a rare inflammatory syndrome in children, with either infectious or autoimmune etiologies. PATIENT:We describe a 7-year-old girl with a presentation of cerebellitis following group A streptococcal infection. RESULTS:Magnetic resonance imaging showed diffuse symmetrical swelling and edema of the cerebellum resulting in compression of the fourth ventricle and hydrocephalus. Autoantibodies against glutamate receptor δ2 were detected in the cerebrospinal fluid, suggesting that the cerebellum might be injured by postinfectious immunologic reaction. The most common causes of cerebellitis are acute viral infection, postinfection, and following vaccination. No examples of acute cerebellitis following group A streptococcal infection have been documented. CONCLUSION:Our report demonstrates that group A streptococcal can lead to acute cerebellitis.

journal_name

Pediatr Neurol

journal_title

Pediatric neurology

authors

Uchizono H,Iwasa T,Toyoda H,Takahashi Y,Komada Y

doi

10.1016/j.pediatrneurol.2013.06.003

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

497-500

issue

6

eissn

0887-8994

issn

1873-5150

pii

S0887-8994(13)00337-8

journal_volume

49

pub_type

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