Increased association between febrile convulsion and allergic rhinitis in children: a nationwide population-based retrospective cohort study.

Abstract:

BACKGROUND AND OBJECTIVES:Febrile convulsions and allergic rhinitis are both common childhood disorders and both are considered as generally benign disorders. Yet, especially in the case of allergic rhinitis, adverse effects on school performance and limited socialization are found. The relationship between febrile convulsions and allergic rhinitis has not been previously reported; thus, this article seeks to explore the association between these two disorders by collecting data from the Taiwanese nationwide cohort database. METHODS:A total of 1304 children with febrile convulsions were identified as the case cohort, and controls were matched based on age, sex, urbanization levels, and parents' occupation on a 1 to 4 ratio. Cox's proportional hazards regression model was used to estimate the hazard ratio and confidence interval of allergic rhinitis disorder among children with febrile convulsions. RESULTS:During an average 6.7 years follow-up period, the incidence of allergic rhinitis in the febrile convulsions case group was higher (65.16 vs 51.45 per 1000 person-years). After 11 years of follow-up, the allergic rhinitis incidence in the febrile convulsion patients was approximate 4% higher than controls (log-rank test P < 0.0001). Risk of allergic rhinitis in the febrile convulsions group was found to be 1.21 times higher than in the control group (95% confidence interval, 1.08-1.36). This risk of allergic rhinitis development is further increased (0.94 vs 18.9) with frequency of febrile convulsions-related medical visits (one to three visits vs more than three visits, P < 0.0001). CONCLUSION:Febrile convulsions may be associated with allergic rhinitis occurrence in children. Children with more than three febrile convulsion-related medical visits had a significantly higher cumulative incidence of allergic rhinitis. Both disorders have previously been reported to have similar cytokine profiles and specific viral infection association. More studies are required to explore a possible link between the two disorders.

journal_name

Pediatr Neurol

journal_title

Pediatric neurology

authors

Lin WY,Muo CH,Ku YC,Sung FC,Kao CH

doi

10.1016/j.pediatrneurol.2013.12.011

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

329-33

issue

4

eissn

0887-8994

issn

1873-5150

pii

S0887-8994(13)00749-2

journal_volume

50

pub_type

杂志文章
  • Bilateral neuropathologic changes in a child with hemimegalencephaly.

    abstract::Evaluation of a 7-month-old girl with developmental delay and intractable seizures revealed hemispheric asymmetry and an enlarged right cerebral hemisphere. Because of a history of seizures refractory to medical therapy, she was admitted for right hemispherectomy, but died of complications of surgery. Postmortem brain...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(97)00091-x

    authors: Jahan R,Mischel PS,Curran JG,Peacock WJ,Shields DW,Vinters HV

    更新日期:1997-11-01 00:00:00

  • Balamuthia amebic meningoencephalitis and mycotic aneurysms in an infant.

    abstract::Balamuthia amebic encephalitis is rarely reported in infants. To the best of our knowledge, amebic encephalitis complicated by a mycotic aneurysm was only described once. We report on an 8-month-child with laboratory-confirmed Balamuthia mandrillaris meningoencephalitis, complicated by a mycotic aneurysm of the middle...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2011.05.003

    authors: Hill CP,Damodaran O,Walsh P,Jevon GP,Blyth CC

    更新日期:2011-07-01 00:00:00

  • Outcome of children with prolonged unconsciousness and vegetative states.

    abstract::The outcomes of 60 children unconscious for 90 days or longer following acquired brain injury are reported. Eight children who died had remained in persistent vegetative states. As expected, most neurologic improvement occurred within the first year after injury, although some delayed improvements were observed. Outco...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(93)90104-k

    authors: Kriel RL,Krach LE,Jones-Saete C

    更新日期:1993-09-01 00:00:00

  • Extension reflex of fingers in the newborn.

    abstract::Extension reflex of fingers was tested in several term and preterm infants. This reflex was found to be present as early as 28 weeks gestation in clinically stable preterm infants. Absence of extension reflex in infants is indicative of neurologic problems. ...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(88)90030-6

    authors: Modanlou HD

    更新日期:1988-01-01 00:00:00

  • Epidemiology of severe hearing impairment in a population-based cerebral palsy cohort.

    abstract:BACKGROUND:Comorbidities including hearing impairment occur commonly in individuals with cerebral palsy (CP). METHODS:Hearing impairment was assessed in a registry-derived population-based sample of children with CP. RESULTS:Hearing impairment was documented in 12.7% (27 of 212) with less than a quarter of these (or ...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2014.07.005

    authors: Dufresne D,Dagenais L,Shevell MI,REPACQ Consortium.

    更新日期:2014-11-01 00:00:00

  • Sarcolemmal alpha and gamma sarcoglycan protein deficiencies in Turkish siblings with a novel missense mutation in the alpha sarcoglycan gene.

    abstract:BACKGROUND:The sarcoglycan alpha gene, also known as the adhalin gene, is located on chromosome 17q21; mutations in this gene are associated with limb-girdle muscular dystrophy type 2D. We describe two Turkish siblings with findings consistent with limb-girdle muscular dystrophy type 2D. The evaluation excluded a dystr...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2013.12.024

    authors: Diniz G,Tosun Yildirim H,Akinci G,Hazan F,Ozturk A,Yararbas K,Tukun A

    更新日期:2014-06-01 00:00:00

  • Cortical Language Areas and Plasticity in Pediatric Patients With Epilepsy: A Review.

    abstract::Chronic injury to the brain from seizure activity is associated with decreased language skills in pediatric patients, as measured on neuropsychological tests for language function and academic achievement. This makes the study of language in patients with epilepsy clinically necessary. Functional magnetic resonance im...

    journal_title:Pediatric neurology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pediatrneurol.2017.10.001

    authors: Chou N,Serafini S,Muh CR

    更新日期:2018-01-01 00:00:00

  • Postneonatal epilepsy following amplitude-integrated EEG-detected neonatal seizures.

    abstract::To assess the incidence of postneonatal epilepsy in term infants treated with antiepileptic drugs for neonatal seizure discharges that were detected with amplitude-integrated electroencephalography (aEEG), 206 term infants were monitored using this modality. They received antiepileptic drugs for clinical as well as su...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2004.11.005

    authors: Toet MC,Groenendaal F,Osredkar D,van Huffelen AC,de Vries LS

    更新日期:2005-04-01 00:00:00

  • Vacuum Extraction in Preterm Deliveries and Long-Term Neurological Outcome of the Offspring.

    abstract:BACKGROUND:Concern exists regarding a possible harmful impact of vacuum extraction on the preterm newborn. We aimed to evaluate the long-term pediatric neurodevelopmental outcomes of the preterm offspring after vacuum extraction. METHODS:A population-based cohort analysis was performed comparing the risk for long-term...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2018.12.010

    authors: Schwarzman P,Sheiner E,Wainstock T,Mastrolia SA,Segal I,Landau D,Walfisch A

    更新日期:2019-05-01 00:00:00

  • MRI and CT findings in Krabbe disease.

    abstract::The progression and characteristics of magnetic resonance imaging (MRI) and computed tomographic (CT) findings in 3 patients with infantile Krabbe disease (i.e., globoid cell leukodystrophy or galactocerebroside beta-galactosidase deficiency) are reported. We obtained initial CT and MRI studies when patients demonstra...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(91)90046-n

    authors: Sasaki M,Sakuragawa N,Takashima S,Hanaoka S,Arima M

    更新日期:1991-07-01 00:00:00

  • Serum Neuronal Biomarkers in Neonates With Congenital Heart Disease Undergoing Cardiac Surgery.

    abstract:BACKGROUND:Newborns with congenital heart disease have associated brain damage that affects short-and long-term neurodevelopment. Several neuronal biomarkers exist that could predict brain damage. We investigated the pattern of neuron-specific enolase (NSE) and s100B levels after cardiopulmonary bypass surgery in neona...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2017.04.011

    authors: Trakas E,Domnina Y,Panigrahy A,Baust T,Callahan PM,Morell VO,Munoz R,Bell MJ,Sanchez-de-Toledo J

    更新日期:2017-07-01 00:00:00

  • Association of the nicotinic receptor beta 2 subunit and febrile seizures.

    abstract::The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Mutations in neuronal nicotinic acetylcholine receptor beta 2 subunit have been associated with autosomal dominant nocturnal frontal lobe epilepsies. A major challenge is t...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2003.08.001

    authors: Peng CT,Chou IC,Li CI,Hsu YA,Tsai CH,Tsai FJ

    更新日期:2004-03-01 00:00:00

  • Intracranial and Extracranial Vascular Stenosis as Risk Factors for Stroke in Sickle Cell Disease.

    abstract:BACKGROUND:Prevalence and contribution of intracranial and extracranial arterial stenosis to stroke risk were assessed prospectively in children and young adults with sickle cell disease. METHODS:In this cross-sectional study, children and young adults (mean = 19.4 years) with sickle cell disease underwent neurologica...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2020.10.006

    authors: Schlotman AA,Donahue MJ,Kassim AA,Lee CA,Waddle SL,Pruthi S,Davis LT,Rodeghier M,DeBaun MR,Jordan LC

    更新日期:2021-01-01 00:00:00

  • Muscle pathology and clinical features of the sarcolemmopathies.

    abstract::We report the clinical features and the muscle pathology in 2 patients with congenital muscular dystrophy (CMD) secondary to merosin deficiency and in 2 patients with sarcoglycan (adhalin) deficiency. Electron microscopic examination revealed sarcolemmal defects in non-necrotic muscle fibers in all cases. These pathol...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(96)00265-2

    authors: Fadic R,Waclawik AJ,Lewandoski PJ,Lotz BP

    更新日期:1997-01-01 00:00:00

  • Social preferences in Rett syndrome.

    abstract::Children with Rett syndrome manifest profound impairments in their ability to speak and use their hands, and exhibit a very limited repertoire of abilities to express themselves, to be neuropsychologically tested, and consequently to be understood. This study examined nonverbal cognitive abilities and visual preferenc...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2012.01.011

    authors: Djukic A,McDermott MV

    更新日期:2012-04-01 00:00:00

  • Epilepsy and fragile X gene mutations.

    abstract::We used two strategies to investigate a possible link between predisposition for epilepsy and mutations in the fragile X mental retardation-1 gene. The first entailed performing electroencephalography on 14 patients with an amplification in the fragile X mental retardation-1 gene, and the second involved molecular gen...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(96)00251-2

    authors: Kluger G,Böhm I,Laub MC,Waldenmaier C

    更新日期:1996-11-01 00:00:00

  • Focal MRI findings in early SSPE.

    abstract::Many investigators have identified localized cortical involvement in subacute sclerosing panencephalitis (SSPE) by clinical and electrophysiologic criteria. Some investigators have reported such abnormalities in the posterior cerebrum early in the course of the disease, but without radiologic correlation. Recently, ma...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(87)90074-9

    authors: Geller TJ,Vern BA,Sarwar M

    更新日期:1987-09-01 00:00:00

  • MRI abnormalities in Behr syndrome.

    abstract::The etiology of Behr syndrome remains uncertain. A 6-year-old girl with a progressive syndrome of optic atrophy, ataxia, myoclonic epilepsy, urinary incontinence, and pyramidal tract degeneration suggestive of Behr syndrome is described. Diffuse, symmetric white matter abnormalities were demonstrated by magnetic reson...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(94)90033-7

    authors: Marzan KA,Barron TF

    更新日期:1994-05-01 00:00:00

  • Pediatric tumefactive demyelination: case series and review of the literature.

    abstract::Tumefactive demyelinating lesions may be misdiagnosed as brain neoplasms or abscesses. In this paper, we present four cases of pediatric tumefactive demyelination. Twelve cases of pediatric tumefactive demyelination previously reported in the English literature are also summarized. We describe the neuroimaging charact...

    journal_title:Pediatric neurology

    pub_type: 杂志文章,评审

    doi:10.1016/s0887-8994(01)00322-8

    authors: McAdam LC,Blaser SI,Banwell BL

    更新日期:2002-01-01 00:00:00

  • Mild encephalopathy with splenial lesion and parainfluenza virus infection.

    abstract::Mild encephalopathy with reversible splenial lesions has mainly been associated with influenza A and B virus infection. Patients present with neurologic symptoms 1 to 3 days after a prodromal illness and recover completely within a few days. Magnetic resonance imaging typically shows reversible lesions with reduced di...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2012.11.007

    authors: Abenhaim Halpern L,Agyeman P,Steinlin M,El-Koussy M,Grunt S

    更新日期:2013-03-01 00:00:00

  • Congenital muscular dystrophies: clinical review and proposed classification.

    abstract::The clinical spectrum of the congenital muscular dystrophies is reviewed using as a sample population 10 Sicilian patients with various clinical subtypes. A comprehensive classification scheme for the muscular dystrophies is presented based on recent advances in our understanding of this heterogeneous group of syndrom...

    journal_title:Pediatric neurology

    pub_type: 杂志文章,评审

    doi:10.1016/0887-8994(95)00148-9

    authors: Parano E,Pavone L,Fiumara A,Falsaperla R,Trifiletti RR,Dobyns WB

    更新日期:1995-09-01 00:00:00

  • Atypical Prodromal Symptoms Help to Distinguish Patients With Psychogenic Nonsyncopal Collapse Among Youth Referred for Fainting.

    abstract:BACKGROUND:Distinguishing patients with psychogenic nonsyncopal collapse (PNSC), a conversion disorder that resembles syncope, can pose a difficult clinical challenge. Using the open-ended question "what does it feel like to faint?," the present study aimed to characterize how patients with PNSC perceive and communicat...

    journal_title:Pediatric neurology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pediatrneurol.2019.02.006

    authors: Heyer GL

    更新日期:2019-06-01 00:00:00

  • Lactate attenuates neuron specific enolase elevation in newborn rats.

    abstract::This study was undertaken to investigate the protective role of lactate on the hypoxic brain in newborn rats. A total of 107 7-day-old Wistar rats were divided into three groups. The lactate accumulation group was given 5% oxygen and 95% nitrogen for 30 minutes. The lactate elimination group was given 5% oxygen, a con...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(99)00039-9

    authors: Ohki S,Togari H,Sobajima H,Fujimoto S,Kobayashi M,Hyodo J

    更新日期:1999-08-01 00:00:00

  • Phenotypes and Genotypes in Five Children with Congenital Insensitivity to Pain with Anhidrosis.

    abstract:BACKGROUND:Congenital insensitivity to pain with anhidrosis is an extremely rare hereditary disorder linked to variants in NTRK1. Our goal was to characterize the clinical features and the genetic basis of the disorder in Chinese patients. METHODS:Patients were enrolled via social networking. Clinical features were in...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2016.04.006

    authors: Wang QL,Guo S,Duan G,Ying Y,Huang P,Liu JY,Zhang X

    更新日期:2016-08-01 00:00:00

  • First U.S. case of adenylosuccinate lyase deficiency with severe hypotonia.

    abstract::Adenylosuccinate lyase (ASL) deficiency is a defect in purine de novo synthesis pathway. The disease has variable clinical presentation involving psychomotor retardation, seizures, hypotonia, and autism. The presence of succinyladenosine and succinylaminoimidazole carboxamide riboside (SAICA riboside) in body fluids c...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(97)89979-1

    authors: Valik D,Miner PT,Jones JD

    更新日期:1997-04-01 00:00:00

  • Intraparenchymal cerebral cysticercosis in children: a benign prognosis.

    abstract::This paper reports 26 consecutive cases of cerebral cysticercosis in children, 21 presenting with intraparenchymal mass lesions, two with encephalitic disease, and three with intraventricular (racemous) cysticercosis. The intraparenchymal and encephalitic forms of the disease were benign. Regression of the lesions occ...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(85)90054-2

    authors: Mitchell WG,Snodgrass SR

    更新日期:1985-05-01 00:00:00

  • Post-traumatic vertigo in children: a diagnostic approach.

    abstract::The relatively high incidence of persistent post-traumatic headache and vertigo in children and adolescents presents a diagnostic and therapeutic challenge. It is often difficult to differentiate between functional complaints generated by psychological trauma or compensation-seeking and symptoms reflecting an organic ...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/0887-8994(86)90058-5

    authors: Eviatar L,Bergtraum M,Randel RM

    更新日期:1986-03-01 00:00:00

  • Subclinical rhythmic EEG discharge of adults: SREDA in two children.

    abstract::Subclinical rhythmic electroencephalogram (EEG) discharge is an uncommon rhythmic EEG pattern that has been reported to occur in adults. It is thought to be a nonspecific finding with little clinical significance. This article reports this EEG pattern in two children and suggests it be called subclinical rhythmic EEG ...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(01)00238-7

    authors: Nagarajan L,Gregory PB,Hewitt IK,Gubbay SS,Parry TS

    更新日期:2001-04-01 00:00:00

  • Changes in brainstem auditory evoked response latencies in term neonates with hyperbilirubinemia.

    abstract::Ninety term neonates with hyperbilirubinemia were studied with brainstem auditory evoked response to clarify the ototoxic effect of hyperbilirubinemia, and detect any differences in ototoxic effect between different levels of total serum bilirubin. The response threshold in these neonates was significantly elevated (P...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/j.pediatrneurol.2007.03.006

    authors: Jiang ZD,Chen C,Liu TT,Wilkinson AR

    更新日期:2007-07-01 00:00:00

  • Vitamins ameliorate secondary mitochondrial failure in neonatal rat brain.

    abstract::Recirculation after transient intrauterine ischemia has previously been found to be accompanied by secondary mitochondrial dysfunction in the immature rat brain. This study was performed to assess the efficacy of combined treatment with ascorbic acid and alpha-tocopherol in improving secondary brain damage. On the 17t...

    journal_title:Pediatric neurology

    pub_type: 杂志文章

    doi:10.1016/s0887-8994(02)00383-1

    authors: Nakai A,Shibazaki Y,Taniuchi Y,Oya A,Asakura H,Koshino T,Araki T

    更新日期:2002-07-01 00:00:00