Abstract:
BACKGROUND:Acute disseminated encephalomyelitis (ADEM) is an immune-mediated, inflammatory acquired demyelinating syndrome predominantly affecting the white matter of the central nervous system. METHODS:We describe a three-year-old boy whose clinical presentation was suspicious for ADEM but whose initial imaging abnormalities were confined to the deep gray matter (without evidence of white matter involvement). His clinical course was fluctuating and repeat imaging one week after presentation demonstrated interval development of characteristic white matter lesions. RESULTS:Treatment with adjunctive intravenous immunoglobulin and high-dose corticosteroids resulted in significant clinical improvement. CONCLUSIONS:Isolated deep gray matter involvement can precede the appearance of white matter abnormalities of ADEM, suggesting that repeat imaging is indicated in individuals whose findings are clinically suspicious for ADEM but who lack characteristic imaging findings.
journal_name
Pediatr Neuroljournal_title
Pediatric neurologyauthors
Abu Libdeh A,Goodkin HP,Ramirez-Montealegre D,Brenton JNdoi
10.1016/j.pediatrneurol.2016.12.006subject
Has Abstractpub_date
2017-03-01 00:00:00pages
64-67eissn
0887-8994issn
1873-5150pii
S0887-8994(16)30722-6journal_volume
68pub_type
杂志文章abstract::Syncope is a common problem in children and adolescents. It is typically caused by benign neurally mediated hypotension, but other, more concerning, etiologies of syncope must be considered. In most instances, the underlying cause of syncope in the pediatric patient can be determined by obtaining a thorough history an...
journal_title:Pediatric neurology
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2008.11.007
更新日期:2009-04-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
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journal_title:Pediatric neurology
pub_type: 杂志文章
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
pub_type: 杂志文章,评审
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2014.10.026
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2019.04.004
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journal_title:Pediatric neurology
pub_type: 杂志文章
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journal_title:Pediatric neurology
pub_type: 杂志文章
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journal_title:Pediatric neurology
pub_type: 杂志文章,评审
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更新日期:2002-11-01 00:00:00
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journal_title:Pediatric neurology
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doi:10.1016/s0887-8994(02)00424-1
更新日期:2002-10-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2007.09.016
更新日期:2008-02-01 00:00:00
abstract::Mitochondrial encephalopathies may be caused by mutations in the respiratory chain complex I subunit genes. Described here are the cases of two pediatric patients who presented with MELAS-like calcarine lesions in addition to novel, bilateral rolandic lesions and epilepsia partialis continua, secondary to MT-ND3 mutat...
journal_title:Pediatric neurology
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/0887-8994(91)90031-f
更新日期:1991-11-01 00:00:00
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/0887-8994(91)90068-v
更新日期:1991-09-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2009.10.010
更新日期:2010-03-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/s0887-8994(98)00114-3
更新日期:1999-02-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2004.09.005
更新日期:2005-02-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/s0887-8994(99)00151-4
更新日期:2000-03-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2004.11.003
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Pediatric patients with epilepsy are at risk for low vitamin D levels, increasing the risk for bone fractures, yet standardized bone health screening is not part of routine care. METHODS:We surveyed pediatric neurologists (n = 68) at our center regarding screening practices, using an 11-item survey; constru...
journal_title:Pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.pediatrneurol.2019.06.020
更新日期:2020-01-01 00:00:00
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journal_title:Pediatric neurology
pub_type: 杂志文章,评审
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