The toxicity, in vitro, of silicon carbide whiskers.

Abstract:

:To mouse cells in culture, SiC whiskers (SiCW) and asbestos are similarly cytotoxic, disrupting cell membranes and killing cells. Both shorten cell generation time, increase the rate of DNA synthesis, increase total cell DNA content, and cause a loss in growth control often associated with malignant cellular transformation. Within the narrow size range of materials examined, the amount of damage appeared to be more a function of the number of whiskers present than of their size. Silicon carbide whiskers, if mishandled, may pose a serious health hazard to humans.

journal_name

Environ Res

journal_title

Environmental research

authors

Vaughan GL,Jordan J,Karr S

doi

10.1016/s0013-9351(05)80109-4

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

57-67

issue

1

eissn

0013-9351

issn

1096-0953

pii

S0013-9351(05)80109-4

journal_volume

56

pub_type

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