Mathematical model of electrotonic interactions during excitation and repolarisation of myocardial tissue.

Abstract:

:A discrete model has been developed which reproduces the intercellular electrophysiological processes within a block of myocardial tissue. The behaviour of individual elements is introduced in the form of the digitised physiologic and premature action potentials which are comprehended as series of jumps between discrete polarisation levels. For each cellular element, the model introduces the excitation threshold as the minimum electric flow in the surrounding which can excite the cell, and the sensitivity towards the electronic interactions which can advance or slow down the depolarisation and repolarisation processes of the cell. The excitation threshold and the electronic sensitivity are dependent on the current polarity of the element. The numerical solution of the model does not use a fixed time slicing integration but is based on discrete planning of asynchronous events. The time increments are dynamically computed according to the chosen precision of the discrete polarity levels. The model enables efficient stimulation of the electrophysiological properties in three-dimensional models of the myocardial tissue. The paper presents a detailed formal description of the model.

authors

Malik M

doi

10.1016/0169-2607(91)90070-a

subject

Has Abstract

pub_date

1991-06-01 00:00:00

pages

111-23

issue

2

eissn

0169-2607

issn

1872-7565

pii

0169-2607(91)90070-A

journal_volume

35

pub_type

杂志文章
  • A fourth order PDE based fuzzy c- means approach for segmentation of microscopic biopsy images in presence of Poisson noise for cancer detection.

    abstract:BACKGROUND AND OBJECTIVE:For cancer detection from microscopic biopsy images, image segmentation step used for segmentation of cells and nuclei play an important role. Accuracy of segmentation approach dominate the final results. Also the microscopic biopsy images have intrinsic Poisson noise and if it is present in th...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.05.003

    authors: Kumar R,Srivastava S,Srivastava R

    更新日期:2017-07-01 00:00:00

  • Minimal ensemble based on subset selection using ECG to diagnose categories of CAN.

    abstract:BACKGROUND AND OBJECTIVE:Early diagnosis of cardiac autonomic neuropathy (CAN) is critical for reversing or decreasing its progression and prevent complications. Diagnostic accuracy or precision is one of the core requirements of CAN detection. As the standard Ewing battery tests suffer from a number of shortcomings, r...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2018.01.019

    authors: Abawajy J,Kelarev A,Yi X,Jelinek HF

    更新日期:2018-07-01 00:00:00

  • Entropy analysis of muscular near-infrared spectroscopy (NIRS) signals during exercise programme of type 2 diabetic patients: quantitative assessment of muscle metabolic pattern.

    abstract::Diabetes mellitus (DM) is a metabolic disorder that is widely rampant throughout the world population these days. The uncontrolled DM may lead to complications of eye, heart, kidney and nerves. The most common type of diabetes is the type 2 diabetes or insulin-resistant DM. Near-infrared spectroscopy (NIRS) technology...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2013.08.018

    authors: Molinari F,Acharya UR,Martis RJ,De Luca R,Petraroli G,Liboni W

    更新日期:2013-12-01 00:00:00

  • A new approach for the real-time simulation of tissue deformations in surgery simulation.

    abstract::Simulation of the behaviour of elastic objects in real time is one of the present objectives of computer graphics. One of its fields of application lies in virtual reality, mainly in surgery simulation systems. Models used for the construction of objects with deformable behaviour in computer graphics are known as defo...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/s0169-2607(00)00093-6

    authors: Monserrat C,Meier U,Alcañiz M,Chinesta F,Juan MC

    更新日期:2001-02-01 00:00:00

  • Corrigendum to "Transportation of magnetized micropolar hybrid nanomaterial fluid flow over a Riga curface surface" [Comput Meth Prog Bio 185 (2020) 105,136].

    abstract::This corrigendum corrects the dimensions of partial differential equations in the paper [1], where these mistakes are occurred during typing processes. But the results in [1] does not affect the scientific and mathematical validity of the paper. ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 信件

    doi:10.1016/j.cmpb.2019.105251

    authors: Abbas N,Malik MY,Nadeem S

    更新日期:2020-04-01 00:00:00

  • Prognostic value of tumor volume for patients with advanced lung cancer treated with chemotherapy.

    abstract:BACKGROUND AND OBJECTIVE:We aim to develop a reference system utilizing computed tomography to calculate changes in tumor volume of lung cancer patients after chemotherapy to assist physicians in clinical treatment and evaluation. METHODS:Image processing techniques were used to analyze the computed tomography of lung...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.03.021

    authors: Kuo CJ,Ke BH,Wu NY,Kuo J,Hsu HH

    更新日期:2017-06-01 00:00:00

  • Detecting negation and scope in Chinese clinical notes using character and word embedding.

    abstract:BACKGROUND AND OBJECTIVES:Researchers have developed effective methods to index free-text clinical notes into structured database, in which negation detection is a critical but challenging step. In Chinese clinical records, negation detection is particularly challenging because it may depend on upstream Chinese informa...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2016.11.009

    authors: Kang T,Zhang S,Xu N,Wen D,Zhang X,Lei J

    更新日期:2017-03-01 00:00:00

  • Robust real time eye tracking for computer interface for disabled people.

    abstract::Gaze is a natural input for a Human Computer Interface (HCI) for disabled people, who have of course an acute need for a communication system. An efficient eye tracking procedure is presented providing a non-invasive method for real time detection of a subject eyes in a sequence of frames captured by low cost equipmen...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2009.03.010

    authors: De Santis A,Iacoviello D

    更新日期:2009-10-01 00:00:00

  • Single subject image analysis using the complex general linear model--an application to functional magnetic resonance imaging with multiple inputs.

    abstract::A linear time invariant model is applied to functional fMRI blood flow data. Based on traditional time series analysis, this model assumes that the fMRI stochastic output sequence can be determined by a constant plus a linear filter (hemodynamic response function) of several fixed deterministic inputs and an error ter...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2005.12.003

    authors: Rio DE,Rawlings RR,Woltz LA,Salloum JB,Hommer DW

    更新日期:2006-04-01 00:00:00

  • Benchmarking of a T-wave alternans detection method based on empirical mode decomposition.

    abstract:BACKGROUND AND OBJECTIVE:T-wave alternans (TWA) is a fluctuation of the ST-T complex occurring on an every-other-beat basis of the surface electrocardiogram (ECG). It has been shown to be an informative risk stratifier for sudden cardiac death, though the lack of gold standard to benchmark detection methods has promote...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.04.005

    authors: Blanco-Velasco M,Goya-Esteban R,Cruz-Roldán F,García-Alberola A,Rojo-Álvarez JL

    更新日期:2017-07-01 00:00:00

  • A mobile computer aided system for optic nerve head detection.

    abstract:BACKGROUND AND OBJECTIVE:The detection of optic nerve head (ONH) in retinal fundus images plays a key role in identifying Diabetic Retinopathy (DR) as well as other abnormal conditions in eye examinations. This paper presents a method and its associated software towards the development of an Android smartphone app base...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2018.05.004

    authors: Elloumi Y,Akil M,Kehtarnavaz N

    更新日期:2018-08-01 00:00:00

  • Prediction of hemodynamic changes towards PEEP titrations at different volemic levels using a minimal cardiovascular model.

    abstract::A cardiovascular system model and parameter identification method have previously been validated for porcine experiments of induced pulmonary embolism and positive end-expiratory pressure (PEEP) titrations, accurately tracking all the main hemodynamic trends. In this research, the model and parameter identification pr...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2008.03.004

    authors: Starfinger C,Chase JG,Hann CE,Shaw GM,Lambert P,Smith BW,Sloth E,Larsson A,Andreassen S,Rees S

    更新日期:2008-08-01 00:00:00

  • A propagation-DNN: Deep combination learning of multi-level features for MR prostate segmentation.

    abstract:BACKGROUND AND OBJECTIVE:Prostate segmentation on Magnetic Resonance (MR) imaging is problematic because disease changes the shape and boundaries of the gland and it can be difficult to separate the prostate from surrounding tissues. We propose an automated model that extracts and combines multi-level features in a dee...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2018.12.031

    authors: Yan K,Wang X,Kim J,Khadra M,Fulham M,Feng D

    更新日期:2019-03-01 00:00:00

  • The effect of particulate matter size on cardiovascular health in Taipei Basin, Taiwan.

    abstract:BACKGROUND:Although the overall effect of particulate matter (PM) on cardiovascular disease (CVD) has been previously documented, the effect of different PM sizes (PM10, PM2.5-10 and PM2.5) has not been well studied. This study estimates the effect of different PM sizes on the incidence of CVD in Taipei, Taiwan. METHO...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2016.08.014

    authors: Yang HC,Chang SH,Lu R,Liou DM

    更新日期:2016-12-01 00:00:00

  • GREMET: an integrative tool for the prediction of mutation effects on gene regulation.

    abstract::The identification of thousands of mutations yearly has put new challenges to researchers who are interested in fast and effective annotation as well as the prediction of potential implications to the gene regulation mechanisms. This work presents an integrative tool, called GREMET, for the prediction of alterations i...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2013.04.002

    authors: Athanasiadis P,Malousi A,Kouidou S,Maglaveras N

    更新日期:2013-07-01 00:00:00

  • Darcy-Forchheimer hybrid (MoS2, SiO2) nanofluid flow with entropy generation.

    abstract:BACKGROUND:The aim of this articles is to investigate the entropy optimization in Darcy-Forchheimer hybrid nanofluids flow towards a stretchable surface. The flow is caused due to stretching of surface. Energy equation is discussed through heat generation/absorption, viscous dissipation and heat flux. Here molybdenum d...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2019.105152

    authors: Khan SA,Khan MI,Hayat T,Alsaedi A

    更新日期:2020-03-01 00:00:00

  • Unique identification code for medical fundus images using blood vessel pattern for tele-ophthalmology applications.

    abstract:BACKGROUND AND OBJECTIVE:Identification of fundus images during transmission and storage in database for tele-ophthalmology applications is an important issue in modern era. The proposed work presents a novel accurate method for generation of unique identification code for identification of fundus images for tele-ophth...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2016.07.011

    authors: Singh A,Dutta MK,Sharma DK

    更新日期:2016-10-01 00:00:00

  • Encryption-free data transmission and hand-over in two-tier body area networks.

    abstract:BACKGROUND AND OBJECTIVE:Deployment of Body Area Networks (BAN) in hospitals can enable real time data collection and analysis for patient health. Such networks have a two-tier structure: the primary layer consists of nodes that are installed on hospital facilities, while the second tier contains sensors on patient bod...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2020.105411

    authors: Wang W,Qin T,Wang Y

    更新日期:2020-08-01 00:00:00

  • Classification of auditory selective attention using spatial coherence and modular attention index.

    abstract:BACKGROUND AND OBJECTIVE:Brain-Computer Interfaces (BCIs) based on auditory selective attention have been receiving much attention because i) they are useful for completely paralyzed users since they do not require muscular effort or gaze and ii) focusing attention is a natural human ability. Several techniques - such ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2018.10.002

    authors: de Souza AP,Soares QB,Felix LB,Mendes EMAM

    更新日期:2018-11-01 00:00:00

  • Development of a 3-D measurement and evaluation system for facial forms with a liquid crystal range finder.

    abstract::A 3-D measurement and evaluation system for facial forms was developed with a liquid crystal range finder (LCRF). Its mechanical resolution was approximately/= 0.4 mm, and it was capable of measuring >30000 points from the entire facial surface in one second. An original program was developed to identify facial landma...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/s0169-2607(98)00064-9

    authors: Yamada T,Sugahara T,Mori Y,Minami K,Sakuda M

    更新日期:1999-02-01 00:00:00

  • The evaluation of artificial intelligence systems in medicine.

    abstract::This paper discusses the underlying issues in the evaluation of computer systems which apply artificial intelligence in medicine. Three different levels of evaluation are described: the subjective evaluation of the research contribution of a developmental prototype, the validation of a system's knowledge and performan...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:

    authors: Miller PL

    更新日期:1986-03-01 00:00:00

  • Adaptive blood glucose control for intensive care applications.

    abstract::Control of blood glucose concentration for patients in intensive care units (ICUs) has been demonstrated to be beneficial in reducing mortality and the incidence of serious complications, for both diabetic and non-diabetic patients. However, the high degree of variability and uncertainty characterizing the physiologic...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2012.01.011

    authors: Ottavian M,Barolo M,Zisser H,Dassau E,Seborg DE

    更新日期:2013-02-01 00:00:00

  • Hospital-wide PACS with a digital image intensifier TV system.

    abstract::Tokyo Hitachi Hospital, Hitachi Ltd., has used a hospital-wide PACS for over 1 year. The system runs a 100 Mb/s optical fiber network over the whole hospital including wards and outpatient clinic rooms, with 11 image workstations. The network links digital imaging modalities such as X-CT, MRI, computed radiography (CR...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(94)90190-2

    authors: Okaniwa H,Tsuneyoshi H,Kabata S,Satoh K,Yokouchi H,Okabe T

    更新日期:1994-05-01 00:00:00

  • Attitude of Iranian physicians and nurses toward a clinical decision support system for pulmonary embolism and deep vein thrombosis.

    abstract::This research project sought to design and implement a computerized clinical decision support system (CDSS) that was able to identify patients who were at risk of pulmonary embolism (PE) and deep vein thrombosis (DVT), as well as produce reminders for prophylactic action for these diseases. The main purpose of the CDS...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2014.03.007

    authors: Agharezaei Z,Bahaadinbeigy K,Tofighi S,Agharezaei L,Nemati A

    更新日期:2014-07-01 00:00:00

  • Compressed sampling for heart rate monitoring.

    abstract::For the first time compressed sampling (CS) has been applied to heart rate (HR) measurements. The signals can be reconstructed from samples far below the Nyquist rate with negligible small errors, a sampling reduction of 8 has been demonstrated in the paper. As a result, the bitrate of the CS sampler is half when comp...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2012.06.002

    authors: Faust O,Acharya UR,Ma J,Min LC,Tamura T

    更新日期:2012-12-01 00:00:00

  • Optimized model tuning in medical systems.

    abstract::In medical systems it is often advantageous to utilize specific problem situations (cases) in addition to or instead of a general model. Decisions are then based on relevant past cases retrieved from a case memory. The reliability of such decisions depends directly on the ability to identify cases of practical relevan...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/s0169-2607(05)80003-3

    authors: Kléma J,Kubalík J,Lhotská L

    更新日期:2005-12-01 00:00:00

  • Mathematical modelling, parameter estimation and computational simulation for skin wound healing under Copaiferalangsdorffi treatments.

    abstract::We present three mathematical models which simulate the wound healing time for 10% oil-resin (10% OR), 10% hydroalcoholic extract (10% EH) (Copaifera langsdorffii drugs), Lanette cream (LC) and Collagenase treatments. Wound healing is a complex process consisting of inflammatory, proliferative and remodelling phases. ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2020.105915

    authors: de Oliveira MH,Gushiken LFS,Pellizzon CH,Mancera PFA

    更新日期:2020-12-26 00:00:00

  • Separation of P300 event-related potential using time varying time-lag blind source separation algorithm.

    abstract::Synchronous averaging over time locked single-trial of event-related potential (ERP) is known as the simplest scheme to extract P300 component. This method assumes the P300 features are invariant through the time while they are affected by factors like brain fatigue and habitation. In this study, a new scheme is propo...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.04.014

    authors: Sabeti M,Boostani R

    更新日期:2017-07-01 00:00:00

  • Comparative analysis of active contour and convolutional neural network in rapid left-ventricle volume quantification using echocardiographic imaging.

    abstract::In cardiology, ultrasound is often used to diagnose heart disease associated with myocardial infarction. This study aims to develop robust segmentation techniques for segmenting the left ventricle (LV) in ultrasound images to check myocardium movement during heartbeat. The proposed technique utilizes machine learning ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2020.105914

    authors: Zhu X,Wei Y,Lu Y,Zhao M,Yang K,Wu S,Zhang H,Wong KKL

    更新日期:2020-12-17 00:00:00

  • Object-oriented design and programming in medical decision support.

    abstract::The concept of object-oriented design and programming has recently received a great deal of attention from the software engineering community. This paper highlights the realisable benefits of using the object-oriented approach in the design and development of clinical decision support systems. These systems seek to bu...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(91)90093-9

    authors: Heathfield H,Armstrong J,Kirkham N

    更新日期:1991-12-01 00:00:00