Increased cell-free DNA concentrations in patients with obstructive sleep apnea.

abstract：:Inpatients with sleep disturbances in a geriatric hospital received 1 h of exposure to approximately 8000 lx bright light per day for 3 weeks. Polysomnogram was recorded for four female patients. Two (aged 68 and 87 years) were non-demented patients with weak cataracts and the other two (aged 92 and 93 years) were dem...

journal_title：Psychiatry and clinical neurosciences

authors： Fukuda N,Kobayashi R,Kohsaka M,Honma H,Sasamoto Y,Sakakibara S,Koyama E,Nakamura F,Koyama T

更新日期：2001-06-01 00:00:00

abstract：AIM:It is difficult to diagnose dementia with Lewy bodies (DLB) because it exhibits clinical and neuropathological overlap with both Alzheimer's disease and Parkinson's disease. The α-synuclein protein is a major component of Lewy bodies, and accumulation of α-synuclein aggregates causes synaptic dysfunction in DLB. Ep...

journal_title：Psychiatry and clinical neurosciences

authors： Funahashi Y,Yoshino Y,Yamazaki K,Mori Y,Mori T,Ozaki Y,Sao T,Ochi S,Iga JI,Ueno SI

更新日期：2017-01-01 00:00:00

abstract：:This study investigated the hypnotic effects of 10 mg melatonin and placebo, which were administered at 10.00 h, according to a single-blind crossover design, on an 8-h diurnal sleep from 11.00 to 19.00 h, following a full night of sleep. The subjects were six healthy male students, each of whom underwent polysomnogra...

journal_title：Psychiatry and clinical neurosciences

authors： Matsumoto M

更新日期：1999-04-01 00:00:00

abstract：AIM:There is some evidence that age and gender influence expression of schizotypal traits in the normal population. One important limitation of previous studies, however, is the restricted age range of subjects. The aim of the present study was therefore to investigate the effect of gender and age on schizotypal person...

journal_title：Psychiatry and clinical neurosciences

authors： Bora E,Baysan Arabaci L

更新日期：2009-10-01 00:00:00

abstract：:Twenty-seven patients with Alzheimer-type dementia (ATD) were treated with bright light therapy in the morning for four consecutive weeks. The cognitive state of each patient was evaluated with the Mini-Mental-State Examination (MMSE) and circadian rhythm with actigram before and after therapy for all of the patients ...

journal_title：Psychiatry and clinical neurosciences

authors： Yamadera H,Ito T,Suzuki H,Asayama K,Ito R,Endo S

更新日期：2000-06-01 00:00:00

abstract：:The aim of this study was to investigate the effect of sociodemographic factors, physical factors and mental factors on the physical and social disability of patients attending outpatient clinics of general hospitals. Physical and psychiatric morbidity in 1580 consecutive patients attending the internal medicine depar...

journal_title：Psychiatry and clinical neurosciences

authors： Sata M,Yoshitake K,Utsunomiya H,Hatada K,Ohtsuka T,Sugasaki H,Nakane Y

更新日期：1999-12-01 00:00:00

abstract：AIM:This preliminary study was performed to test the reliability and validity of the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB), developed by the National Institute of Mental Health MATRICS initiative, as an assessment tool in a Japanese-languag...

journal_title：Psychiatry and clinical neurosciences

authors： Kaneda Y,Ohmori T,Okahisa Y,Sumiyoshi T,Pu S,Ueoka Y,Takaki M,Nakagome K,Sora I

更新日期：2013-04-01 00:00:00

abstract：:The present study tested the potential association between the 3111C/T polymorphism of the CLOCK gene and seasonal variations in mood and behavior. A total of 297 Korean college students were genotyped for the CLOCK polymorphism and the seasonal variation was evaluated using the Seasonal Pattern Assessment Questionnai...

journal_title：Psychiatry and clinical neurosciences

authors： Paik JW,Lee HJ,Kang SG,Lim SW,Lee MS,Kim L

更新日期：2007-02-01 00:00:00

abstract：:The present study was aimed to clarify the differences in clinical implications between wrist- and arm-cutting. Subjects were 201 delinquent adolescents (178 males and 23 females) who had been admitted to a detention center from February to March 2003. A self-reporting questionnaire and the Adolescent Dissociative Exp...

journal_title：Psychiatry and clinical neurosciences

authors： Matsumoto T,Yamaguchi A,Chiba Y,Asami T,Iseki E,Hirayasu Y

更新日期：2004-08-01 00:00:00

abstract：AIM:To determine the differences in the remission rate, recovery rate, functional improvement, and treatment adherence related to treatment with short-acting immediate-release methylphenidate (IR-MPH) and long-acting osmotic-release oral system-methylphenidate (OROS-MPH) in a naturalistic setting among Taiwanese childr...

journal_title：Psychiatry and clinical neurosciences

authors： Tzang RF,Wang YC,Yeh CB,Hsu CD,Liang HY,Yang PC,Liu HJ,Huang YS,Cheng H,Hsu YC,Liu SI,Pan CH,Huang YF,Huang CF,Wu YY,Huang YH,Liu HC,Chang HL

更新日期：2012-02-01 00:00:00

abstract：:A new mathematical method was developed to analyze time series. Applications of this method to the delta component of all-night sleep electroencephalogram (EEG) revealed new variations with double-rapid eye movement (REM)-sleep interval. The proposed method entails repeated application of the least squares spectrum. F...

journal_title：Psychiatry and clinical neurosciences

authors： Koga E,Tsuji Y

更新日期：1998-10-01 00:00:00

abstract：:Several countries, such as the USA, inadvertently created a different behavioral health payment system from the rest of medicine through the introduction of diagnostic-related group exemptions for psychiatric care. This led to isolation in the administration and delivery of care for patients with mental health and sub...

journal_title：Psychiatry and clinical neurosciences

authors： Kishi Y,Kathol RG,McAlpine DD,Meller WH,Richards SW

更新日期：2006-06-01 00:00:00

abstract：:We describe the test-retest reliability of the Personality Diagnostic Questionnaire: Revised (PDQ-R), which was developed to assess DSM-III-R personality disorders (PD). Thirty patients, diagnosed clinically with PD, filled out the PDQ-R twice at 1 month intervals after having undergone 8 weeks of treatment leading to...

journal_title：Psychiatry and clinical neurosciences

authors： Uehara T,Sakado K,Sato T

更新日期：1997-12-01 00:00:00

abstract：AIMS:Antidepressants have been of limited use for adolescent subjects with depression because of drug-induced suicide-related events (SRE). Therefore, we investigated actual suicidality and its risk factors during antidepressant therapy among child and adolescent patients in clinical settings. METHODS:The risks of SRE...

journal_title：Psychiatry and clinical neurosciences

authors： Kuba T,Yakushi T,Fukuhara H,Nakamoto Y,Singeo ST Jr,Tanaka O,Kondo T

更新日期：2011-04-01 00:00:00

abstract：AIM:This systematic review and meta-analysis evaluated whether bright light therapy (BLT) is an effective and safe treatment for manic/depressive symptoms and a preventive measure for recurrent mood episodes in patients with bipolar disorder. METHODS:A literature search of major electronic databases was conducted in J...

journal_title：Psychiatry and clinical neurosciences

authors： Takeshima M,Utsumi T,Aoki Y,Wang Z,Suzuki M,Okajima I,Watanabe N,Watanabe K,Takaesu Y

更新日期：2020-04-01 00:00:00

abstract：AIMS:To investigate the correlation between the incidence of post-stroke depression (PSD) and the levels of substance P (SP) in the plasma and cerebrospinal fluid (CSF). METHODS:Ninety-one stroke patients were divided into PSD (n = 46) and post-stroke (without depression) groups (n = 45). PSD must have occurred 2-4 we...

journal_title：Psychiatry and clinical neurosciences

authors： Li L,Gao X,Zhao J,Ji X,Wei H,Luo Y

更新日期：2009-06-01 00:00:00

abstract：:The purpose of the present study was to investigate the neural substrates underlying event-related potential (ERP) abnormalities, with respect to the generators of the ERP components in depressed patients. Using an oddball paradigm, ERP from auditory stimuli were recorded from 22 unmedicated patients with current depr...

journal_title：Psychiatry and clinical neurosciences

authors： Kawasaki T,Tanaka S,Wang J,Hokama H,Hiramatsu K

更新日期：2004-02-01 00:00:00

abstract：AIM:This study examined catechol-O-methyltransferase (COMT) DNA methylation in the peripheral blood of schizophrenia patients and also in healthy controls to investigate its potential use as a peripheral biomarker of schizophrenia and its relations with the clinical variables of schizophrenia patients. METHODS:We exam...

journal_title：Psychiatry and clinical neurosciences

authors： Nour El Huda AR,Norsidah KZ,Nabil Fikri MR,Hanisah MN,Kartini A,Norlelawati AT

更新日期：2018-04-01 00:00:00

abstract：AIMS:Long-term use of methamphetamine could induce psychosis, but consequences with regards to intelligence have seldom been investigated. Long-term use of alcohol could also result in intellectual deterioration. METHODS:The IQ of 34 methamphetamine-induced psychosis (MIP) patients (age, 28.7 +/- 6.1 years) and 34 alc...

journal_title：Psychiatry and clinical neurosciences

authors： Lin SK,Huang MC,Lin HC,Pan CH

更新日期：2010-02-01 00:00:00

abstract：:Schizotypal personality disorder (SPD) has rarely been reported as an eating disorder-related personality trait. A 23-year-old woman was diagnosed as having anorexia nervosa binge eating/purging type. At the age of 53 years, she was admitted to Jikei University Hospital because of excessive bodyweight loss. She was di...

journal_title：Psychiatry and clinical neurosciences

authors： Nagata T,Ono K,Nakayama K

更新日期：2007-08-01 00:00:00

abstract：AIMS:This 12-week open-label study was designed to investigate the pharmacokinetics and efficacy of a direct switch from a conventional depot to long-acting injectable risperidone in patients with schizophrenia and schizoaffective disorder. METHODS:Men or women from 18 to 65 years old with a diagnosis of schizophrenia...

journal_title：Psychiatry and clinical neurosciences

authors： Lai YC,Huang MC,Chen CH,Tsai CJ,Pan CH,Chiu CC

更新日期：2009-08-01 00:00:00

abstract：AIMS:Alcohol use is the third highest risk factor for disease and disability. This study explored the association between binge drinking and mental health, general health, and diet and nutrition of young adults. METHODS:A sub-sample of 2590 adults aged 18-29 years was selected from 10 364 participants in the survey to...

journal_title：Psychiatry and clinical neurosciences

authors： Mohamed S,Ajmal M

更新日期：2015-08-01 00:00:00

abstract：:A high disease burden of mental disorders has been noted worldwide, including Japan. It is important to monitor mental disorder prevalence trends and the use of mental health services over time using epidemiological data and to plan appropriate policies and measures that consider mental health in each country. This re...

journal_title：Psychiatry and clinical neurosciences

authors： Nishi D,Ishikawa H,Kawakami N

更新日期：2019-08-01 00:00:00

abstract：:Subjective sleep feelings and motor activity were measured in seven healthy elderly subjects for 6 days. The subjects were exposed to bright light (6000 lux) for 30 min in the morning or instructed to sit in front of a desktop lighting device without light. The average level of motor activity during the night was sign...

journal_title：Psychiatry and clinical neurosciences

authors： Kohsaka M,Fukuda N,Kobayashi R,Honma H,Sakakibara S,Koyama E,Nakano O,Matsubara H

更新日期：1998-04-01 00:00:00

abstract：:The effects of phenobarbital (PB; doses, 5, 10, and 25 mg/kg, intraperitoneally (i.p.)) and zonisamide (ZNS; doses, 30, 75, and 150 mg/kg, i.p.) on nitric oxide (NO) production, and those of coadministration of PB (5 mg/kg, i.p.) and ZNS (75 mg/kg, i.p.) on monoamines in the brain of the seizure-susceptible EL mouse w...

journal_title：Psychiatry and clinical neurosciences

authors： Tominaga M,Nagatomo I,Uchida M,Hashiguchi W,Akasaki Y,Takigawa M

更新日期：2001-08-01 00:00:00

abstract：:A preliminary study on the Noh mask test for analysis of recognition of facial expression was performed. The present study was conducted on 15 normal subjects (mean age: 32 years, SD 9.7 years) as the first step to test for the differences between psychiatric patients and normal subjects. Stimuli were created by photo...

journal_title：Psychiatry and clinical neurosciences

authors： Minoshita S,Satoh S,Morita N,Tagawa A,Kikuchi T

更新日期：1999-02-01 00:00:00

abstract：:From our practice at the sleep disorders clinic in Kohnodai Hospital, National Center of Neurology and Psychiatry (NCNP), we report the clinical characteristics of circadian sleep-wake rhythm disorders. Nearly 90% of circadian rhythm sleep disorders were diagnosed as delayed sleep phase syndrome (DSPS) or as non-24 sl...

journal_title：Psychiatry and clinical neurosciences

authors： Kamei Y,Urata J,Uchiyaya M,Hayakawa T,Ozaki S,Shibui K,Okawa M

更新日期：1998-04-01 00:00:00

abstract：:MicroRNA may play a role in the pathophysiology of schizophrenia. A recent meta-analysis of genome-wide association studies indicated a significant association between schizophrenia and a common intronic variation in MIR137HG (microRNA 137 host gene) encoding the primary microRNA-137. To explore additional risk variat...

journal_title：Psychiatry and clinical neurosciences

authors： Egawa J,Nunokawa A,Shibuya M,Watanabe Y,Kaneko N,Igeta H,Someya T

更新日期：2013-05-01 00:00:00

abstract：AIMS:The purpose of the present study was to investigate sleep structure in post-traumatic stress disorder (PTSD) patients with and without any psychiatric comorbidities. The relationship between sleep variables and measurements of clinical symptom severity were also investigated. METHODS:Sleep patterns of 24 non-medi...

journal_title：Psychiatry and clinical neurosciences

authors： Yetkin S,Aydin H,Ozgen F

更新日期：2010-06-01 00:00:00

abstract：AIMS:Near-infrared spectroscopy has the potential for aiding the diagnosis of major depressive disorder. The purpose of this study was to systematically review the evidence from observational studies regarding the use of near-infrared spectroscopy in patients with major depressive disorder and to identify the character...

journal_title：Psychiatry and clinical neurosciences

authors： Zhang H,Dong W,Dang W,Quan W,Tian J,Chen R,Zhan S,Yu X

更新日期：2015-01-01 00:00:00