DNA methylation changes at SNCA intron 1 in patients with dementia with Lewy bodies.

abstract：:The present study was purposed to identify the prevalence of restless legs syndrome (RLS) and its associated factors in the Korean adult population. Among a total of 9939 participants derived from the Korean Health and Genome Study, 12.1% of subjects (men, 8.5%; women, 15.4%) suffered from RLS. Factors independently r...

journal_title：Psychiatry and clinical neurosciences

authors： Kim J,Choi C,Shin K,Yi H,Park M,Cho N,Kimm K,Shin C

更新日期：2005-06-01 00:00:00

abstract：:Sporadic temporal slow waves are considered to be associated with mild cerebrovascular dysfunction. However, electroencephalogram (EEG) changes have not been consistently described by some investigators and correlations inferred on the basis of such data remain inconclusive. In the present study, we examined previousl...

journal_title：Psychiatry and clinical neurosciences

authors： Inui K,Motomura E,Kaige H,Nomura S

更新日期：2001-10-01 00:00:00

abstract：:Atypical antipsychotics are rapidly evolving to become the standard pharmacotherapy in schizophrenia; however, the trend of switching to such drugs is not necessarily progressing quickly in East Asia. This might be due to the scarcity of evidence for the efficacy of switching from conventional to atypical antipsychoti...

journal_title：Psychiatry and clinical neurosciences

authors： Nakanishi S,Kunugi H,Murray RM,Nojima S,Ogawa T,Takahashi T

更新日期：2006-12-01 00:00:00

abstract：:The relationship between the entorhinal cortex and prepulse inhibition (PPI) as well as the nucleus accumbens dopaminergic participation in acoustic startle were examined in rats. After the entorhinal cortex was damaged bilaterally using ibotenic acid, a microdialysis probe was placed in the nucleus accumbens for dete...

journal_title：Psychiatry and clinical neurosciences

authors： Goto K,Ueki A,Iso H,Morita Y

更新日期：2004-08-01 00:00:00

abstract：AIMS:Several variables are able to influence the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS), particularly the intensity of stimulation, which is generally expressed according to the resting motor threshold (RMT). The aim of our study was to investigate whether or not RMT changes durin...

journal_title：Psychiatry and clinical neurosciences

authors： Pretalli JB,Nicolier M,Chopard G,Vandel P,Tio G,Monnin J,Pazart L,Sechter D,Haffen E

更新日期：2012-06-01 00:00:00

abstract：AIMS:Alterations in cortisol and dehydroepiandrosterone sulfate (DHEA-S) levels are thought to play a role in the pathophysiology of neuropsychiatric disorders, including schizophrenia. The aim of this study was to investigate the role of serum cortisol and DHEA-S in the pathophysiology of schizophrenia. METHODS:Sixty...

journal_title：Psychiatry and clinical neurosciences

authors： Yıldırım O,Dogan O,Semiz M,Kilicli F

更新日期：2011-10-01 00:00:00

abstract：AIMS:Another structure in the obsessive-compulsive disorder (OCD) circuit may be the pituitary gland because of the fact that limbic-hypothalamic-pituitary-adrenal (LHPA) axis abnormality has been reported in patients with OCD. There has been only one prior study, however, concerning pituitary volumetry, in which the s...

journal_title：Psychiatry and clinical neurosciences

authors： Atmaca M,Yildirim H,Ozler S,Koc M,Kara B,Sec S

更新日期：2009-08-01 00:00:00

abstract：:Rapid eye movement sleep behavior disorder (RBD) is a parasomnia with clinical symptoms that include punching, kicking, yelling and leaping out of bed in sleep. Polysomnographic (PSG) finding showed REM sleep without muscle atonia. Clonazepam is generally used for treating RBD symptoms but melatonin was reported to be...

journal_title：Psychiatry and clinical neurosciences

authors： Takeuchi N,Uchimura N,Hashizume Y,Mukai M,Etoh Y,Yamamoto K,Kotorii T,Ohshima H,Ohshima M,Maeda H

更新日期：2001-06-01 00:00:00

abstract：AIM:This study examined catechol-O-methyltransferase (COMT) DNA methylation in the peripheral blood of schizophrenia patients and also in healthy controls to investigate its potential use as a peripheral biomarker of schizophrenia and its relations with the clinical variables of schizophrenia patients. METHODS:We exam...

journal_title：Psychiatry and clinical neurosciences

authors： Nour El Huda AR,Norsidah KZ,Nabil Fikri MR,Hanisah MN,Kartini A,Norlelawati AT

更新日期：2018-04-01 00:00:00

abstract：:A modified version of the Waldrop scale (WS) was used to assess the prevalence of minor physical anomalies in schizophrenic patients (n = 71) and healthy controls (n = 65). The mean total WS score was 3.32 (SD 1.98) for the schizophrenic patients, significantly higher than that for the controls (2.19, SD 1.18). Minor ...

journal_title：Psychiatry and clinical neurosciences

authors： Hata K,Iida J,Iwasaka H,Negoro HI,Ueda F,Kishimoto T

更新日期：2003-02-01 00:00:00

abstract：:The purpose of the present paper was to investigate the role and attitude of people who accompanied geriatric patients to an outpatient psychiatric clinic. The study was conducted at a large university hospital in Taiwan. Participants included 108 patients aged 65 years and older who were seen for their initial psychi...

journal_title：Psychiatry and clinical neurosciences

authors： Chen CY,Chen YJ,Juang YY,Liu CY,Hung CI

更新日期：2004-06-01 00:00:00

abstract：:Two cases of tardive dystonia are reported. The first case was an 18-year-old schizophrenic woman suffering from parkinsonism and hypotension induced by antipsychotic drugs. Risperidone (4 mg/day) was added to her drug regimen and after increasing the dosage to 6 mg/day, she began to exhibit retrocollis. The second ca...

journal_title：Psychiatry and clinical neurosciences

authors： Tachikawa H,Suzuki T,Kawanishi Y,Hori M,Hori T,Shiraishi H

更新日期：2000-08-01 00:00:00

abstract：AIMS:The reasons for accessing and maintaining access to mental health services in Japan may be different to those in other countries. Using the World Health Organization World Mental Health Japan survey data, this study investigated the prevalence of sociodemographic correlates of barriers for the use of, reasons for ...

journal_title：Psychiatry and clinical neurosciences

authors： Kanehara A,Umeda M,Kawakami N,World Mental Health Japan Survey Group.

更新日期：2015-09-01 00:00:00

abstract：:Using urethane-anaesthetized rats, the effects of acupunctural stimulation to the sacral segment on the urinary bladder activity and cortical electroencephalogram (EEG) were examined. The acupuncture suppressed urinary bladder activity in 36 of 68 trials. On many occasions (22/36 trials), suppression was accompanied b...

journal_title：Psychiatry and clinical neurosciences

authors： Tanaka Y,Koyama Y,Jodo E,Kayama Y,Kawauchi A,Ukimura O,Miki T

更新日期：2002-06-01 00:00:00

abstract：:This study investigated the hypnotic effects of 10 mg melatonin and placebo, which were administered at 10.00 h, according to a single-blind crossover design, on an 8-h diurnal sleep from 11.00 to 19.00 h, following a full night of sleep. The subjects were six healthy male students, each of whom underwent polysomnogra...

journal_title：Psychiatry and clinical neurosciences

authors： Matsumoto M

更新日期：1999-04-01 00:00:00

abstract：AIM:The orexigenic hormone, ghrelin, is linked to learning and memory in animal studies. No previous study has investigated whether cognition is related to ghrelin in the non-demented elderly. METHODS:Thirty-five older adults underwent neuropsychological testing and fasting blood draw with subsequent serum ghrelin qua...

journal_title：Psychiatry and clinical neurosciences

authors： Spitznagel MB,Benitez A,Updegraff J,Potter V,Alexander T,Glickman E,Gunstad J

更新日期：2010-12-01 00:00:00

abstract：:The evidence to date on the relation between the risk of venous thromboembolic disease (VTE) and antipsychotic agents derives primarily from observational and case history studies. While an increased risk of VTE has been associated with first-generation low-potency antipsychotic agents, particularly clozapine, there a...

journal_title：Psychiatry and clinical neurosciences

authors： Masopust J,Malý R,Vališ M

更新日期：2012-12-01 00:00:00

abstract：AIMS:The present study was designed to investigate quality of life (QOL) among caregivers of cancer inpatients, and to explore the related factors with the long-term goal to improve QOL of cancer caregivers in China. METHODS:A cross-sectional study was performed during the period January-March 2008. Subjects comprised...

journal_title：Psychiatry and clinical neurosciences

authors： Lu L,Pan B,Sun W,Cheng L,Chi T,Wang L

更新日期：2010-10-01 00:00:00

abstract：AIMS:This 12-week open-label study was designed to investigate the pharmacokinetics and efficacy of a direct switch from a conventional depot to long-acting injectable risperidone in patients with schizophrenia and schizoaffective disorder. METHODS:Men or women from 18 to 65 years old with a diagnosis of schizophrenia...

journal_title：Psychiatry and clinical neurosciences

authors： Lai YC,Huang MC,Chen CH,Tsai CJ,Pan CH,Chiu CC

更新日期：2009-08-01 00:00:00

abstract：:Hikikomori, a severe form of social withdrawal, has long been observed in Japan mainly among youth and adolescents since around the 1970s, and has been especially highlighted since the late 1990s. Moreover, hikikomori-like cases have recently been reported in many other countries. Hikikomori negatively influences not ...

journal_title：Psychiatry and clinical neurosciences

authors： Kato TA,Kanba S,Teo AR

更新日期：2019-08-01 00:00:00

abstract：AIMS:The purpose of the present study was to investigate sleep structure in post-traumatic stress disorder (PTSD) patients with and without any psychiatric comorbidities. The relationship between sleep variables and measurements of clinical symptom severity were also investigated. METHODS:Sleep patterns of 24 non-medi...

journal_title：Psychiatry and clinical neurosciences

authors： Yetkin S,Aydin H,Ozgen F

更新日期：2010-06-01 00:00:00

abstract：:The main purpose of the present study was to investigate the diagnostic concepts of taijin-kyofu-sho (TKS) and social phobia, by comparing the clinical diagnosis of TKS and the operational diagnosis of Diagnostic and Statistical Manual of Mental Disorders (3rd edition, revised; DSM-III-R). Three evaluators conducted s...

journal_title：Psychiatry and clinical neurosciences

authors： Nakamura K,Kitanishi K,Miyake Y,Hashimoto K,Kubota M

更新日期：2002-12-01 00:00:00

abstract：AIM:Neuroimaging-based multivariate pattern-recognition methods have been successfully used to develop diagnostic algorithms to distinguish patients with major depressive disorder (MDD) from healthy controls (HC). We developed and evaluated the accuracy of a multivariate classification method for the differentiation of...

journal_title：Psychiatry and clinical neurosciences

authors： Ramasubbu R,Brown EC,Marcil LD,Talai AS,Forkert ND

更新日期：2019-08-01 00:00:00

abstract：:Little is known about the neuronal mechanism underpinning the pathophysiology of compulsive hoarding. We report the cerebral blood flow changes in an obsessive-convulsive patient with severe hoarding. The patient showed hyperperfusion of the fronto-temporal region and hypoperfusion of the striatal, the middle cingulat...

journal_title：Psychiatry and clinical neurosciences

authors： Ohtsuchi H,Matsuo K,Akimoto T,Watanabe Y

更新日期：2010-10-01 00:00:00

abstract：AIM:To elucidate the factors associated with insomnia symptoms and the use of sleep medication, and the correlations among insomnia symptoms, sleep medication use and depressive symptoms in the general population. METHODS:This survey was conducted in a rural community of Japan. Questionnaires consisted of basic inform...

journal_title：Psychiatry and clinical neurosciences

authors： Komada Y,Nomura T,Kusumi M,Nakashima K,Okajima I,Sasai T,Inoue Y

更新日期：2011-02-01 00:00:00

abstract：:Delusions associated with cerebrovascular diseases have been sporadically reported. Although both psychiatrists and neurologists attempted to link delusions with anatomical locations of the brain lesion, comorbid psychiatric and neurological disorders make the interpretation of delusions difficult. The purpose of the ...

journal_title：Psychiatry and clinical neurosciences

authors： Su KP,Hsu CY,Hsieh SC,Shen WW

更新日期：2001-04-01 00:00:00

abstract：AIMS:Long-term use of methamphetamine could induce psychosis, but consequences with regards to intelligence have seldom been investigated. Long-term use of alcohol could also result in intellectual deterioration. METHODS:The IQ of 34 methamphetamine-induced psychosis (MIP) patients (age, 28.7 +/- 6.1 years) and 34 alc...

journal_title：Psychiatry and clinical neurosciences

authors： Lin SK,Huang MC,Lin HC,Pan CH

更新日期：2010-02-01 00:00:00

abstract：AIMS:To investigate the correlation between the incidence of post-stroke depression (PSD) and the levels of substance P (SP) in the plasma and cerebrospinal fluid (CSF). METHODS:Ninety-one stroke patients were divided into PSD (n = 46) and post-stroke (without depression) groups (n = 45). PSD must have occurred 2-4 we...

journal_title：Psychiatry and clinical neurosciences

authors： Li L,Gao X,Zhao J,Ji X,Wei H,Luo Y

更新日期：2009-06-01 00:00:00

abstract：:We report cases of four patients with mild obstructive sleep apnea syndrome (OSAS) with frequent breathing-related electroencephalogram (EEG) arousals which led to excessive daytime sleepiness. In spite of a relatively low apnea hypopnea index (AHI), sleep was disrupted by frequent EEG arousals associated with respira...

journal_title：Psychiatry and clinical neurosciences

authors： Mikami A,Watanabe T,Motonishi M,Honda H,Kyotani K,Uruha S,Terashima K,Teshima Y,Sugita Y,Takeda M

更新日期：1999-04-01 00:00:00

abstract：:The purpose of the present study was to investigate the prevalence, distribution of psychiatric diagnoses, and treatment responses of patients with post-partum mental illness at an emergency unit at Chang Gung Memorial Hospital at Kaohsiung in Taiwan. During a 1 year period a total of 636 Taiwanese women received psyc...

journal_title：Psychiatry and clinical neurosciences

authors： Lai JY,Huang TL

更新日期：2004-04-01 00:00:00