Skin biopsy as a diagnostic tool.

abstract：PURPOSE OF REVIEW:For a long time, cognitive impairment in multiple sclerosis patients has been considered less important than, for instance, physical disability. This is no longer true because of the crucial role that cognitive deficits play in the good day-to-day adjustment of patients. This review highlights recent ...

journal_title：Current opinion in neurology

authors： Hoffmann S,Tittgemeyer M,von Cramon DY

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to review recent publications on amyotrophic lateral sclerosis (ALS). RECENT FINDINGS:The Awaji recommendations for electrophysiological diagnosis will permit earlier clinical trials entry. The use of ultrasound to visualize fasciculations, even in deep muscles, will contribute to earlier ...

journal_title：Current opinion in neurology

authors： de Carvalho M,Swash M

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The traditional focus of neurorehabilitaion has been on the patients' attention on their deficit, such that they should become aware of their problems and gain intentional control of compensatory strategies (descending approach). We review prism adaptation as one of the approaches that emphasize ascen...

journal_title：Current opinion in neurology

authors： Pisella L,Rode G,Farnè A,Tilikete C,Rossetti Y

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to review sleep disturbances in different movement disorders, mainly Parkinson's disease, and highlight current concepts on merging the boundaries between movement disorders and dissociative states of being. RECENT FINDINGS:Since the observation that rapid eye movement sleep behavior disor...

journal_title：Current opinion in neurology

authors： Giannoccaro MP,Antelmi E,Plazzi G

更新日期：2013-08-01 00:00:00

abstract：:Primary germ-cell tumors of the central nervous system are rare neoplasms that are seen primarily in the pediatric age group. Because of their frequent location in the pituitary and suprasellar regions, they present with typical neuro-ophthalmologic and neuroendocrine symptoms. Sophisticated imaging and surgical biops...

journal_title：Current opinion in neurology

authors： Hooda BS,Finlay JL

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cervical artery dissection (CeAD) is a major cause of ischemic stroke in young and middle-aged adults, although relatively uncommon in the community. Recent large collaborative projects have provided new insights into mechanisms and risk factors of CeAD. RECENT FINDINGS:Pathologic changes observed at...

journal_title：Current opinion in neurology

authors： Debette S

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review of recent work in the area of neurorehabilitation of multiple sclerosis patients surveys progress and underscores the need for further work to evaluate the effectiveness of treatments. RECENT FINDINGS:Several recent review documents have summarized the current position regarding neuroreha...

journal_title：Current opinion in neurology

authors： Thompson AJ

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Localization of focal epileptic brain is critical for successful epilepsy surgery and focal brain stimulation. Despite significant progress, roughly half of all patients undergoing focal surgical resection, and most patients receiving focal electrical stimulation, are not seizure free. There is intens...

journal_title：Current opinion in neurology

authors： Cimbalnik J,Kucewicz MT,Worrell G

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Ten years of intensive research are now beginning to bring candidate neuroprotective therapies to clinical trials. This review describes recent progress in basic, preclinical, and clinical research that underlies current and potential neuroprotective trials. RECENT FINDINGS:Basic research continues t...

journal_title：Current opinion in neurology

authors： Hersch SM

更新日期：2003-08-01 00:00:00

abstract：:In the past few years evidence that atherosclerotic disease of the aortic arch is probably an underestimate source of emboli, particularly moving thrombi in the lumen, has accumulated. Pathological studies, and more recently transesophageal echocardiographic studies, have shown that atherosclerotic disease of the aort...

journal_title：Current opinion in neurology

authors： Heinzlef O,Cohen A,Amarenco P

更新日期：1997-02-01 00:00:00

abstract：:A relatively small number of studies were published on the intra-arterial therapy of stroke in the past year. Those reports, however, do offer strong evidence for the feasibility and safety of this therapeutic approach. Partly on the basis of these data it has become evident that the intra-arterial thrombolytic therap...

journal_title：Current opinion in neurology

authors： Abou-Chebl A,Furlan AJ

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic and often disabling neuropathy, which often responds to immune therapies including corticosteroids, plasma exchange, and high-dose intravenous immunoglobulin (IVIg). The reasons for choosing one of these therapies and the fa...

journal_title：Current opinion in neurology

authors： Nobile-Orazio E,Gallia F

更新日期：2015-10-01 00:00:00

abstract：:Little progress has been made in the treatment outcome of patients with glioblastoma in the past 10 to 15 years, despite an aggressive multimodality regimen using surgery, radiation, and chemotherapy. New approaches, particularly molecular strategies, have become the clinicians' and scientists' hope for the future in ...

journal_title：Current opinion in neurology

authors： Yung WK

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review some aspects of the relationship between epilepsy and depression that have recently received increasing attention and may become major research topics in the near future. RECENT FINDINGS:Epidemiological studies show that depression and suicide are, in some cases, premorbid symptoms precedin...

journal_title：Current opinion in neurology

authors： Mula M

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to assess the seizure manifestations and risk of epilepsy in encephalitis associated with antibodies against neuronal cell-surface (autoimmune encephalitis) or myelin-associated antigens, and to review several chronic epileptic disorders, including Rasmussen's encephalitis, f...

journal_title：Current opinion in neurology

authors： Spatola M,Dalmau J

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The concept of epilepsy and seizure disorders caused by autoantibodies to specific neuronal membrane proteins has developed significantly during the past few years. RECENT FINDINGS:Antibodies to cell-surface membrane proteins such as voltage-gated potassium channels or N-methyl-D-aspartate receptors,...

journal_title：Current opinion in neurology

authors： Vincent A,Irani SR,Lang B

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:With the aging of the population, treatment of painful neuropathies is becoming more and more important for neurological practice. This short review highlights recent findings and current problems. RECENT FINDINGS:In addition to tricyclic antidepressants and gabapentin, the reliability of which is es...

journal_title：Current opinion in neurology

authors： Cruccu G

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the present use of interventional transcatheter strategies to treat patients with acute brain ischemia and severe stenosis of intracranial large arteries. RECENT FINDINGS:The benefits and risks of opening freshly occluded intracranial large arteries in patients with brain ischem...

journal_title：Current opinion in neurology

authors： Caplan LR,Thomas AJ,Inoa V

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the extensive research carried out in the past decades, the current pathophysiological notions of neurodegenerative disease as well as effective treatments to reduce their progression are largely unknown. Alterations of the human microbiota, the plethora of different microscopic organisms that...

journal_title：Current opinion in neurology

authors： Marizzoni M,Provasi S,Cattaneo A,Frisoni GB

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Gliomas represent a disparate group of malignancies with varying clinical outcomes despite a tremendous amount of time, effort, and resources dedicated to their management and understanding. The most aggressive entity, glioblastoma, has a dismal prognosis with poor local control despite intense local ...

journal_title：Current opinion in neurology

authors： Beckta JM,Bindra RS,Chalmers AJ

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review considers the role of neuroimaging in developmental disorders by highlighting recent studies in two distinct, but overlapping, developmental disorders: autism and fragile X syndrome. RECENT FINDINGS:After a decade of conflicting results in neuroimaging studies of autism, recent studies ha...

journal_title：Current opinion in neurology

authors： Greicius MD

更新日期：2003-04-01 00:00:00

abstract：:Ablative surgery and deep brain stimulation for Parkinson's disease can be performed in the thalamus, the pallidum and the subthalamic nucleus. The efficacy and safety of unilateral pallidotomy is well established. Deep brain stimulation has a lower morbidity and is preferred for bilateral surgery. The subthalamic nuc...

journal_title：Current opinion in neurology

authors： Krack P,Hamel W,Mehdorn HM,Deuschl G

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on our knowledge regarding prevention and management of medication overuse headache (MOH). RECENT FINDINGS:The prevalence of MOH is 1-2% in the general population worldwide, and because of the tremendous socio-economic cost, it is likely to be the most costly neurologic...

journal_title：Current opinion in neurology

authors： Russell MB,Lundqvist C

更新日期：2012-06-01 00:00:00

abstract：:Various functional imaging modalities can be applied in acute ischaemic stroke to identify functionally impaired, but morphologically preserved tissue (i.e. the penumbra), and to distinguish it from irreversibly damaged tissue. Flow thresholds for irreversible tissue destruction resulting in functional impairment, as ...

journal_title：Current opinion in neurology

authors： Heiss WD,Forsting M,Diener HC

更新日期：2001-02-01 00:00:00

abstract：:This review centers on important recent advances in the understanding of the role of glial fibrillary acidic protein in Alexander disease and of proteolipid protein in hypomyelinating disorders such as Pelizaeus-Merzbacher and spastic paraplegia. We also describe seven novel leukodystrophies. These include childhood a...

journal_title：Current opinion in neurology

authors： Schiffmann R,Boespflüg-Tanguy O

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The diagnosis of dementia rests on an improved knowledge and a better detection of early impairments, to which functional imaging can certainly contribute. RECENT FINDINGS:Progress has been observed at different levels. First, the understanding of different dementias has benefited from explorations o...

journal_title：Current opinion in neurology

authors： Salmon E

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The diagnosis of amyotrophic lateral sclerosis (ALS) still relies mainly on clinical criteria. In present review we will provide an overview of neurochemical ALS biomarkers, which are in the most advanced position on the way towards inclusion into the clinical work-up. RECENT FINDINGS:The field of AL...

journal_title：Current opinion in neurology

authors： Verde F,Silani V,Otto M

更新日期：2019-10-01 00:00:00

abstract：:This article reviews the current knowledge with regard to neurotoxicity of conventional radiation, including recent understanding of the pathophysiology, molecular biology, diagnostic evaluation and clinical presentations, as well as proposed treatment modalities and possible protective agents. ...

journal_title：Current opinion in neurology

authors： New P

更新日期：2001-12-01 00:00:00

abstract：:The review intends to draw the attention of researchers working in retinal degenerations on the fact that classical apoptosis, for example, apoptosis triggering caspase activation, may not be the main pathway of cellular demise in this tissue.Former work already showed the difficulty of proving the activation of apopt...

journal_title：Current opinion in neurology

authors： Torriglia A,Jaadane I,Lebon C

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The results of phase 2 randomized controlled trials for the prevention of episodic and chronic migraine demonstrating the efficacy and safety of four mAbs targeting the calcitonin gene-related peptide (CGRP) pathway [ALD403 (eptinezumab), AMG334 (erenumab), LY2951742 (galcanezumab) and TEV48125 (frema...

journal_title：Current opinion in neurology

authors： Mitsikostas DD,Reuter U

更新日期：2017-06-01 00:00:00