Role of different genes in the CS6 operon for surface expression of Enterotoxigenic Escherichia coli colonization factor CS6.

abstract：:DNA vaccination is particularly efficient for induction of cytotoxic T-lymphocyte (CTL) response. In our experiments, we used MHC(B) congenic chicken lines CB and CC (regressors and progressors of v-src-induced tumours, respectively) and a mutated, non-oncogenic v-src gene construct as the DNA vaccine. A high degree o...

journal_title：Vaccine

authors： Plachý JV,Hejnar JV,Trtková K,Trejbalová K,Svoboda J,Hála K

更新日期：2001-08-14 00:00:00

abstract：BACKGROUND:Vaccination against Haemophilus influenzae type b (Hib) is included in routine pediatric immunization schedule in the United States. Previous vaccine shortages have created the need for additional options for Hib vaccination. METHODS:This phase III, randomized, multi-centered study (NCT01000974) evaluated t...

journal_title：Vaccine

authors： Klein NP,Abu-Elyazeed R,Cornish M,Leonardi ML,Weiner LB,Silas PE,Grogg SE,Varman M,Frenck RW,Cheuvart B,Baine Y,Miller JM,Leyssen M,Mesaros N,Roy-Ghanta S

更新日期：2017-06-16 00:00:00

abstract：:Given the ethical aspects of vaccination policies and current threats to public trust in vaccination, it is important that governments follow clear criteria for including new vaccines in a national programme. The Health Council of the Netherlands developed such a framework of criteria in 2007, and has been using this ...

journal_title：Vaccine

authors： Verweij MF,Houweling H

更新日期：2014-12-12 00:00:00

abstract：:To evaluate long-term immunogenicity of a virosomal subunit inactivated influenza vaccine in children with asthma, a prospective study was conducted during 2005-2006 influenza season in six public pediatric clinics in Milan and surroundings, Northern Italy. A single dose (0.5 ml) of a virosomal subunit inactivated inf...

journal_title：Vaccine

authors： Zuccotti G,Amendola A,Viganò A,Pariani E,Zappa A,Pogliani L,Giacomet V,Savarino A,Podestà A,Rottoli A,Tanzi E,Zanetti A,Radaelli G

更新日期：2007-09-17 00:00:00

abstract：:Forty-four adult patients with cutaneous leishmaniasis (CL) were enrolled in a randomized, double-blind, controlled, dose-escalating clinical trial and were randomly assigned to receive three injections of either the LEISH-F1+MPL-SE vaccine (consisting of 5, 10, or 20 μg recombinant Leishmania polyprotein LEISH-F1 ant...

journal_title：Vaccine

authors： Nascimento E,Fernandes DF,Vieira EP,Campos-Neto A,Ashman JA,Alves FP,Coler RN,Bogatzki LY,Kahn SJ,Beckmann AM,Pine SO,Cowgill KD,Reed SG,Piazza FM

更新日期：2010-09-14 00:00:00

abstract：:There are currently no vaccines or therapeutics to prevent dengue disease which ranges in severity from asymptomatic infections to life-threatening illness. The National Institute of Allergy and Infectious Diseases (NIAID) Division of Intramural Research has developed live, attenuated vaccines to each of the four deng...

journal_title：Vaccine

authors： Lindow JC,Durbin AP,Whitehead SS,Pierce KK,Carmolli MP,Kirkpatrick BD

更新日期：2013-07-18 00:00:00

abstract：:In the last quarter of the year 2000, the meningococcal C conjugated vaccine was incorporated into the routine vaccination schedule in Catalonia (at 2, 4 and 6 months). In addition a vaccination campaign was carried out in children <6 years of age, with a coverage of 96.2%. The effectiveness of the vaccination in this...

journal_title：Vaccine

authors： Salleras L,Domínguez A,Cardeñosa N

更新日期：2003-01-30 00:00:00

abstract：BACKGROUND:World Health Organization has recommended the introduction of pneumococcal conjugate vaccine (PCV) in the childhood immunisation programme of all the countries in the world. In lieu of its introduction in India, there is a need to generate evidence on cost-effectiveness of this vaccine. The current study loo...

journal_title：Vaccine

authors： Krishnamoorthy Y,Eliyas SK,Nair NP,Sakthivel M,Sarveswaran G,Chinnakali P

更新日期：2019-01-21 00:00:00

abstract：INTRODUCTION:The Global Vaccine Action Plan (GVAP), unanimously endorsed by the World Health Assembly in 2012, defined an ambitious strategy to improve immunization. At the end of the decade, significant progress has been made but four of the five GVAP goals are likely to be missed. This report describes a set of surve...

journal_title：Vaccine

authors： Hwang A,Veira C,Malvolti S,Cherian T,MacDonald N,Steffen C,Jones I,Hinman A,Mantel C

更新日期：2020-07-14 00:00:00

abstract：:Clostridium difficile infection (CDI) causes nosocomial antibiotic-associated diarrhea and colitis in the developed world. Two potent cytotoxins, toxin A (TcdA) and toxin B (TcdB) are the virulence factors of this disease and can be a good vaccine candidate against CDI. In the present study, we genetically engineered ...

journal_title：Vaccine

authors： Guo S,Yan W,McDonough SP,Lin N,Wu KJ,He H,Xiang H,Yang M,Moreira MA,Chang YF

更新日期：2015-03-24 00:00:00

abstract：BACKGROUND:We evaluated the safety and immunogenicity of liquid and lyophilized formulations of an investigational trivalent group B streptococcus (GBS) vaccine in non-pregnant women and assessed the formulations' equivalence in terms of serotype-specific immune response. METHODS:This phase II, randomized, comparative...

journal_title：Vaccine

authors： Beran J,Leroux-Roels G,Van Damme P,de Hoon J,Vandermeulen C,Al-Ibrahim M,Johnson C,Peterson J,Baker S,Seidl C,Dreisbach A,Karsten A,Corsaro B,Henry O,Lattanzi M,Bebia Z

更新日期：2020-04-03 00:00:00

abstract：:Oral Cholera Vaccine (OCV) has been recognized as an adjunct tool for prevention and control of cholera. However, policy directions are currently unavailable in India to guide the vaccine delivery. We conducted a scoping review to inform the policy about the scopes and challenges of different strategic choices of OCV ...

journal_title：Vaccine

authors： Ray A,Sarkar K,Haldar P,Ghosh R

更新日期：2020-02-29 00:00:00

abstract：:Epidemic meningococcal meningitis is an important public health problem in sub-Saharan Africa. Current control measures rely on reactive immunizations with polysaccharide (PS) vaccines that do not induce herd immunity and are of limited effectiveness in those under 2 years of age. Conversely, polysaccharide conjugate ...

journal_title：Vaccine

authors： LaForce FM,Konde K,Viviani S,Préziosi MP

更新日期：2007-09-03 00:00:00

abstract：:Passive immunization of mice with a monoclonal IgE antibody to Schistosoma japonicum (SJ18 epsilon. 1) induces significant protection to a challenge infection and the target molecule of SJ18 epsilon. 1 is paramyosin. In the present study, we demonstrate the B cell epitope of paramyosin recognized by SJ18 epsilon. 1 by...

journal_title：Vaccine

authors： Nara T,Tanabe K,Mahakunkijcharoen Y,Osada Y,Matsumoto N,Kita K,Kojima S

更新日期：1997-01-01 00:00:00

abstract：:After a single injection of Typhim Vi (typhoid Vi polysaccharide vaccine), serum antibody concentrations were monitored for 3 years in 37 adults who resided where typhoid fever was not endemic. Anti-Vi antibody concentrations declined progressively during the study, to levels that support the current US recommendation...

journal_title：Vaccine

authors： Froeschle JE,Decker MD

更新日期：2010-02-10 00:00:00

abstract：:The objective of the present study was to investigate the feasibility of a subunit vaccine and a live bacteria vaccine to protect chickens against infectious bursal disease virus (IBDV) infection. The gene for VP2 of a new wild-type very virulent IBDV (vvIBDV) strain was cloned into an Escherichia coli expression syst...

journal_title：Vaccine

authors： Rong J,Cheng T,Liu X,Jiang T,Gu H,Zou G

更新日期：2005-09-23 00:00:00

abstract：:Salmonella enterica serovar Typhimurium is a versatile host organism for the generation of recombinant live vaccines for mucosal immunization. We investigated the performance of an intracellular-activated promoter for expression of heterologous antigens by Salmonella carrier strains. We observed that intracellular exp...

journal_title：Vaccine

authors： Husseiny MI,Hensel M

更新日期：2005-04-08 00:00:00

abstract：:The induction of oral tolerance against disease-inducing antigens has emerged as a feasible strategy to prevent immunopathologies. In this study, we investigated the effect of oral immunization with whole antigens of Leishmania amazonensis promastigotes (LaAg) on murine cutaneous leishmaniasis. We found that two oral ...

journal_title：Vaccine

authors： Pinto EF,de Mello Cortezia M,Rossi-Bergmann B

更新日期：2003-09-08 00:00:00

abstract：BACKGROUND:While many clinicians encounter parents or adolescents who refuse HPV vaccine, little is known about the prevalence of hesitancy for HPV vaccine nationally or its association with vaccination. METHODS:In April 2019, we surveyed families with adolescents 11-17 years using a national online panel (Knowledge P...

journal_title：Vaccine

authors： Szilagyi PG,Albertin CS,Gurfinkel D,Saville AW,Vangala S,Rice JD,Helmkamp L,Zimet GD,Valderrama R,Breck A,Rand CM,Humiston SG,Kempe A

更新日期：2020-08-27 00:00:00

abstract：:Numerous evidence demonstrate Type 1 diabetes (T1D) is due to a loss of immune tolerance to islet antigens, and CD8(+) T cells play an important role in the development of T1D in NOD mice. The novel coinhibitory receptor BTLA may have a regulatory role in maintaining peripheral tolerance, however, its role in autoimmu...

journal_title：Vaccine

authors： Li S,Zhang M,Xiang F,Zhao J,Jiang C,Zhu J

更新日期：2011-10-13 00:00:00

abstract：BACKGROUND:Bacillus Calmette-Guérin (BCG) vaccination is a widely-used public health intervention for tuberculosis (TB) control. In Taiwan, like other intermediate TB burden settings, steadily declining TB incidence raises important questions on whether universal BCG vaccination should be discontinued. Recent surveys o...

journal_title：Vaccine

authors： Fu H,Lin HH,Hallett TB,Arinaminpathy N

更新日期：2018-09-18 00:00:00

abstract：:We assessed HPV 16 and 18 antibody responses of female subjects enrolled in a 2- vs. 3-dose quadrivalent HPV (Q-HPV) vaccine trial (ClinicalTrials.gov NCT00501137) using the Merck competitive Luminex (cLIA) and total IgG Luminex (TIgG) immunoassays, and a pseudovirus neutralizing antibody (PsV NAb) assay. Subjects wer...

journal_title：Vaccine

authors： Krajden M,Cook D,Yu A,Chow R,Su Q,Mei W,McNeil S,Money D,Dionne M,Palefsky J,Karunakaran K,Kollmann T,Ogilvie G,Petric M,Dobson S

更新日期：2014-01-23 00:00:00

abstract：:Racial differences in diarrheal disease have not been systematically examined, and the impact of rotavirus vaccine on these differences has not been assessed. We compared diarrhea-associated hospitalizations by race/ethnicity among children <5 years pre- (2000-2006) and post- (2007 and 2008) rotavirus vaccine introduc...

journal_title：Vaccine

authors： Yen C,Steiner CA,Barrett M,Curns AT,Hunter K,Wilson E,Parashar UD

更新日期：2010-10-28 00:00:00

abstract：INTRODUCTION:The World Health Organization recommends that as part of the polio end-game strategy a dose of inactivated poliovirus vaccine (IPV) be introduced by the end of 2015 in all countries currently using only oral poliovirus vaccine (OPV). Administration of fractional dose (1/5 of full dose) IPV (fIPV) by intrad...

journal_title：Vaccine

authors： Resik S,Tejeda A,Mach O,Sein C,Molodecky N,Jarrahian C,Saganic L,Zehrung D,Fonseca M,Diaz M,Alemany N,Garcia G,Hung LH,Martinez Y,Sutter RW

更新日期：2015-10-26 00:00:00

abstract：:There is an urgent need for an effective vaccine against human disease caused by Burkholderia pseudomallei, and although a wide range of candidates have been tested in mice none provide high level protection. We considered this might reflect the inability of these vaccine candidates to protect against chronic disease....

journal_title：Vaccine

authors： Champion OL,Gourlay LJ,Scott AE,Lassaux P,Conejero L,Perletti L,Hemsley C,Prior J,Bancroft G,Bolognesi M,Titball RW

更新日期：2016-03-29 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is the major viral cause of infant and childhood lower respiratory tract disease worldwide. Defining the optimal target product profile (TPP) is complicated due to a wide range of possible vaccine properties, modalities and an incomplete understanding of the mechanism of nat...

journal_title：Vaccine

authors： Pan-Ngum W,Kinyanjui T,Kiti M,Taylor S,Toussaint JF,Saralamba S,Van Effelterre T,Nokes DJ,White LJ

更新日期：2017-01-05 00:00:00

abstract：:We recently reported an attenuated EIAV vaccine study that directly examined the effect of lentiviral envelope sequence variation on vaccine efficacy. The study [1] demonstrated for the first time the failure of an ancestral vaccine to protect and revealed a significant, inverse, linear relationship between envelope d...

journal_title：Vaccine

authors： Craigo JK,Barnes S,Cook SJ,Issel CJ,Montelaro RC

更新日期：2010-11-29 00:00:00

abstract：:Protein based therapeutics have enjoyed great success over the past decade. Unfortunately, with this clinical success comes a heavy price tag, owing to the inherently high costs of capitalization and production using mammalian cell fermentation. To address this problem, we have begun developing a system for the expres...

journal_title：Vaccine

authors： Mayfield SP,Franklin SE

更新日期：2005-03-07 00:00:00

abstract：:In anticipation of the implementation of new prophylactic HPV vaccines, the WHO is supporting the establishment of a global WHO HPV Laboratory Network whose mission is to "contribute to improving the quality of laboratory services for effective surveillance and monitoring of HPV vaccination impact through enhanced, st...

journal_title：Vaccine

authors： Ferguson M,Wilkinson DE,Zhou T

更新日期：2009-01-14 00:00:00

abstract：:Envelope glycoprotein E2 is the most immunogenic protein of classical swine fever virus (CSFV). In a proposed model of the antigenic structure of E2, the N-terminal half of E2 forms two independent structural antigenic units, A and BC. E2 without transmembrane region (E2-TMR) is expressed and secreted into the medium ...

journal_title：Vaccine

authors： van Rijn PA,van Gennip HG,Moormann RJ

更新日期：1999-02-05 00:00:00