Abstract:
:Twenty-three children with diabetes mellitus, their ages ranging from 0.2-9.8 years, but with no sign of diabetic microvascular disease were investigated by M-mode and Doppler echocardiography, along with a comparable group of control subjects. In the diabetics, the fractional shortening and the mean velocity of fractional shortening were 14 and 18% higher, respectively, whereas the left ventricular end-systolic wall stress, an indicator of left ventricular afterload, was markedly reduced (22%). Assuming an unchanged preload in the two groups, this indicates a reduced afterload in these children. Systolic and diastolic time intervals, heart rate, and blood pressure were similar in diabetics and controls. Doppler-derived transmitral left ventricular filling indices were also similar. Thus, in these diabetic children no signs of left ventricular diastolic abnormality were detected. The state of hypercontractility of the left ventricle is considered to be due to a reduced afterload in early insulin-dependent diabetes.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Gøtzsche O,Sørensen K,McIntyre B,Henningsen Pdoi
10.1007/BF02238405subject
Has Abstractpub_date
1991-04-01 00:00:00pages
69-73issue
2eissn
0172-0643issn
1432-1971journal_volume
12pub_type
杂志文章abstract::We herein describe, for the first time, the fetal presentation of a case of ventricular inversion, restrictive ventricular septal defect, pulmonary stenosis, hypertensive left ventricle and double outlet right ventricle at 34 weeks of gestational age. Postnatal echocardiography confirmed the prenatal diagnosis. The pa...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-018-2048-8
更新日期:2019-01-01 00:00:00
abstract::The authors present an unusual complication of the balloon atrial septostomy procedure performed in a neonate with D-transposition of the great arteries. Cardiac tamponade developed shortly after the balloon atrial septostomy procedure and the infant was found to have a tear in the superior aspect of the left atrium, ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02076340
更新日期:1983-04-01 00:00:00
abstract::We report a 6-year-old girl with superoinferior ventricles, criss-cross atrioventricular (AV) relationships with solitus atria, a D-loop, L-transposition of the great arteries, subpulmonary stenosis, but without a ventricular septal defect (VSD). The diagnosis was made by echocardiographic examination and was strength...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00795379
更新日期:1993-10-01 00:00:00
abstract::Intravascular ultrasound (IVUS) has been introduced as an accurate and minimally invasive diagnostic technique for the assessment of vascular anatomy and its abnormalities. We believe that IVUS can be used for clarifying the reasons for failure of balloon angiography in infantile coarctation of the aorta (CoA), becaus...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02503-y
更新日期:2021-01-04 00:00:00
abstract::Atrial flutter/fibrillation (AFL/AF) is a late complication in adults with repaired tetralogy of Fallot (TOF). Its effects on long-term prognosis are not fully understood. We evaluate the impact of AFL/AF in adults with repaired TOF on global mortality and unplanned hospitalizations during follow-up, and the predictor...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02106-2
更新日期:2019-06-01 00:00:00
abstract::Numerous RNA-binding proteins (RBPs) are expressed in the heart, and mutations in several RBPs have been implicated in cardiovascular disease through genetic associations, animal modeling, and mechanistic studies. However, the functions of many more cardiac RBPs, and their relevance to disease states, remain to be elu...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-019-02180-6
更新日期:2019-10-01 00:00:00
abstract::Midodrine hydrochloride is a potent peripherally-acting alpha1 agonist that is well absorbed and rapidly metabolized to its active metabolite. It has been used for the treatment of refractory syncope but has the important side effect of supine hypertension. A 10-year-old boy with severe symptomatic orthostatic hypoten...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-006-0169-y
更新日期:2007-07-01 00:00:00
abstract::The current pulse-oximetry screening (POS) protocol for detection of critical congenital heart defects (CCHDs) is recommended only for newborns in well-infant and intermediate care nurseries, and there is no evidence-based protocol for infants discharged from the neonatal intensive care unit (NICU). The objectives of ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0793-2
更新日期:2014-03-01 00:00:00
abstract::A 6-year-old girl presented with respiratory distress. Chest radiographs exhibited calcifications in the mediastinum. Further imaging revealed extensive cardiac calcifications on computed tomography of the chest. The laboratory parameters were consistent with findings of secondary hyperparathyroidism. Detailed review ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-004-0765-7
更新日期:2005-07-01 00:00:00
abstract::In our institute, 1100 patients with a history of Kawasaki disease have been catheterized for selective coronary arteriography. Their age at examination ranged from four months to 13 years. Coronary artery lesions (CAL) were found in 262 patients. As far as the type of the CAL was concerned, occlusion was noted in 20 ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02315475
更新日期:1986-01-01 00:00:00
abstract::Sudden cardiac death in young competitive athletes is tragic and usually due to unsuspected cardiovascular disease. Screening programs for athletes remain debatable, and restriction of athletes from sports can have physical, emotional, and legal ramifications. In this article, we review the epidemiology of the more co...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-012-0170-6
更新日期:2012-03-01 00:00:00
abstract::We encountered a male aged 6 years 4 months with Kawasaki disease (KD) with severe tricuspid regurgitation and left ventricular dysfunction in the acute phase. His clinical course and findings of endomyocardial biopsy suggested that myocarditis was the cause of left ventricular dysfunction and responsible for the deve...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-002-0137-0
更新日期:2003-01-01 00:00:00
abstract::This report describes the case of a 29-day-old infant with Kawasaki's disease who presented in extremis with multiple coronary aneurysms and coronary thromboses, myocardial ischemia, and congestive heart failure. The infant successfully underwent emergent coronary thrombolysis with tissue plasminogen activator. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9781-y
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:This study aimed to measure and compare right ventricular (RV) function in normal infants and those with pulmonary hypertension (PHT) using the myocardial performance index (RVMPI) and to investigate the relationship between RV function and pulmonary artery pressure. METHODS:A case-control study measured RV...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-008-9285-1
更新日期:2009-02-01 00:00:00
abstract::The morphology and natural history of anomalous right ventricular muscle bundles (ARVMB) have been described in a number of postnatal studies. Whether this is a congenital or acquired cardiac lesion remains obscure. A fetal echocardiogram performed in a 32-week gestation mother showed a large ventricular septal defect...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00795736
更新日期:1994-09-01 00:00:00
abstract::Fifty infants with interrupted aortic arch (IAA), admitted between 1979 and 1988, were reviewed. They usually presented early in severe cardiac failure or shock. In the initial 5-year period, 17 of the 21 infants underwent diagnostic or confirmatory cardiac catheterization, in contrast with the latter 5 years when onl...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00838779
更新日期:1992-10-01 00:00:00
abstract::Use of extracorporeal membrane oxygenation (ECMO) in infants with congenital heart disease is becoming more frequent. We present the first reported use of balloon atrial septostomy during ECMO support and describe possible complications of such procedures unique to ECMO therapy. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00795647
更新日期:1993-07-01 00:00:00
abstract::This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8 kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlant...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00246-014-0905-7
更新日期:2014-10-01 00:00:00
abstract::Sedation/anesthesia is critical to cardiac catheterization in the pediatric/congenital heart patient. We sought to identify current sedation/anesthesia practices, the serious adverse event rate related to airway, sedation, or anesthesia, and the rate of intra-procedural conversion from procedural sedation to the use o...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00246-015-1167-8
更新日期:2015-10-01 00:00:00
abstract::Apelin is an endogenous inotrope that decreased in heart failure (HF). We aimed to evaluate the prognostic value of its level in children with HF due to congenital heart disease (CHD). Sixty children with HF due to CHD were included as a patient group. Sixty healthy children matched for age, sex, and weight served as ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1879-7
更新日期:2018-08-01 00:00:00
abstract::An 11 day-old female infant underwent resection of a mass in the subaortic region secondary to critical aortic stenosis. At 3 months of age, recurrent severe left-ventricular outflow obstruction (LVOT) in the setting of heart failure prompted redo surgery, and the resected mass revealed an intracardiac foregut cyst, w...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0623-y
更新日期:2013-01-01 00:00:00
abstract::Children with congenital heart defects often demonstrate a reduced capacity for exercise, even after surgical intervention. Forty subjects, with various heart defects, completed a 5-year study to evaluate the impact of a postoperative training program on their physical exercise capacity. All of the patients were signi...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02238841
更新日期:1990-07-01 00:00:00
abstract::The congenital anomaly of aortopulmonary window is rare. Its combination with interruption of the aortic arch has been previously recognized and reported in infants and children. Early and complete repair of such a congenital anomaly may prevent progression to cardiac failure and premature death. We describe the succe...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/BF02505097
更新日期:1996-03-01 00:00:00
abstract::We report the case of a fetus diagnosed at 24 weeks' gestation with complete heart block associated with maternal collagen vascular disease and Sjögren's antibody. Serial fetal echocardiograms noted increased echogenicity along the tricuspid and mitral valves without insufficiency. Postnatally, severe tricuspid insuff...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00800677
更新日期:1994-07-01 00:00:00
abstract::Crossed pulmonary arteries (CPAs) are a rare abnormality in which the ostium of the left pulmonary artery originates superior to the right pulmonary artery and to its right. Recognition of this rare pathology is important because it generally is accompanied by other congenital heart defects, extracardiac anomalies, an...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0714-4
更新日期:2013-01-01 00:00:00
abstract::Left-ventricular noncompaction (LVNC) is an echocardiographic finding of increasing frequency in pediatrics; however, predictors of outcomes have been difficult to identify. We conducted a retrospective review of pediatric patients at the Morgan Stanley Children's Hospital of New York from January of 1993 to September...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9868-5
更新日期:2011-04-01 00:00:00
abstract::In the very young child (less than eight years of age), transient loss of consciousness represents a diagnostic and management dilemma for clinicians. While most commonly benign, syncope may be due to cardiac dysfunction which can be life-threatening. It can be secondary to an underlying ion channelopathy, cardiac inf...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-020-02498-6
更新日期:2021-01-02 00:00:00
abstract::Circulating progenitor cells have been extensively studied in the context of heart disease in adults. In these patients, they have been demonstrated to be markers of myocardial injury and recovery as well as potential therapeutic agents. However, studies in children are much more limited. Here we review current knowle...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-015-1300-8
更新日期:2016-02-01 00:00:00
abstract::Near-infrared spectroscopy (NIRS) can monitor changes in cerebral regional oxygen saturation (rSO2) and tissue hemoglobin content (HbT). The relation between cerebral NIRS readings and vital parameters has not been analyzed before at a fine temporal scale. This study analyzed this relation during cardiopulmonary bypas...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0754-9
更新日期:2014-01-01 00:00:00
abstract::This review outlines the morphologic and pathogenetic characteristics of congenital polyvalvular disease. Two cases are used for exemplification. The macroscopic and histologic features of the valves as well as associated cardiac lesions and clinical syndromes are described, followed by a discussion of morphogenesis o...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s002460010169
更新日期:2001-03-01 00:00:00